Inonza 1 mg Injection 1's

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹330000

(Inclusive of all Taxes)

₹39600.0 Cashback (12%)

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Non returnable*

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Whats That

About Inonza 1 mg Injection

Inonza 1 mg Injection is an anti-cancer medicine used in the treatment of acute lymphoblastic leukemia, a blood cancer that primarily affects the blood and bone marrow. Inonza 1 mg Injection is used in the treatment of patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

Inonza 1 mg Injection contains Inotuzumab Ozogamicin, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Inonza 1 mg Injection may cause certain side effects, such as skin rash, fatigue, headache, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, myalgia, and injection site reactions. These side effects do not require medical attention and gradually resolve over time. Inonza 1 mg Injection is a parenteral preparation. It will be administered by a trained oncologist. Do not self-administer.

Inonza 1 mg Injection should be avoided if you are allergic to it or any other components present in it. Before taking Inonza 1 mg Injection, caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, or cardiac problems, as it may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding before starting the treatment.

Uses of Inonza 1 mg Injection

Acute lymphocytic leukemia (ALL).

Directions for Use

A trained and experienced oncologist will administer Inonza 1 mg Injection. Hence, do not self-administer.

Medicinal Benefits

Inonza 1 mg Injection contains Dasatinib, which is used in the treatment of acute lymphoblastic leukemia (ALL). It works by binding the ADC (antibody-drug conjugate) and CD22 tumor cells containing N-acetyl-gamma-calicheamicin (cytotoxic agent) and forms the ADC-CD22 complex. This complex causes the activation of N-acetyl-gamma-calicheamicin and induces DNA breakage. Thus, it helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Storage

Keep Inonza 1 mg Injection out of the sight and reach of children.

Side effects of Inonza 1 mg Injection

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Yellowing of skin and eyes

High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
Exercise regularly to maintain a good metabolism in your body.
Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.

Abnormal liver function test

High levels of liver enzymes need immediate medical attention.
Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
Regularly do strengthening exercises to control your cholesterol levels.
Avoid drinking alcohol as it can affect your liver.
Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
Practice yoga and meditation to improve liver functioning and overall health.

Increased Risk Of Infection Due To Low Neutrophil Count

Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
Avoid contact with people who are sick.
Wash your hands regularly with soap and water.
Avoid unpasteurized dairy products.

Deficiency Of All Types Of Blood Cells (Red Cells, White Cells, And Platelets)

Bone Marrow Failure

High Uric Acid Levels In Blood

Eat a balanced diet: Less liver, seafood, and red meat, and more fruits, vegetables, dairy, and whole grains. Limit sugary treats and drinks.
Drink alcohol in moderation: Too much beer, wine, or spirits can increase uric acid.
Stay hydrated: Drink plenty of water, at least 8-10 glasses daily.
Maintain a healthy weight and exercise regularly to reduce uric acid.
Manage stress with meditation or yoga.
Regular health checks: Monitor uric acid levels and follow up with your doctor to adjust your treatment plan.

Drug Warnings

Inonza 1 mg Injection should be avoided if you are allergic to it or any other components present in it. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, or increased blood pressure, as the use of Inonza 1 mg Injection in these patients may cause serious side effects. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Inonza 1 mg Injection is given in children above one year of age only if prescribed by the doctor. Inonza 1 mg Injection may cause myelosuppression, QT prolongation, hepatotoxicity, Hepatic Veno-occlusive Disease (Sinusoidal Obstruction Syndrome), and Increased Risk of Post-HSCT Non-Relapse Mortality in some patients. Hence, inform your doctor about your complete medical and medication history before receiving this medicine. Avoid alcohol consumption and smoking, which can lead to serious adverse effects.

Drug-Drug Interactions

Inotuzumab ozogamicinMoxifloxacin

Severe

Drug-Drug Interactions

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Inotuzumab ozogamicinMoxifloxacin

Severe

How does the drug interact with Inonza 1 mg Injection:
Using Moxifloxacin together with Inonza 1 mg Injection can increase the risk of an irregular heart Rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Inonza 1 mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - an irregular heartbeat, dizziness, difficulty breathing- make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

After beginning your treatment, several dietary adjustments can help you control side effects.
Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.
Avoid fast and fried food, processed meats, refined carbs and added sugars.

Side Effects of Inonza 1 mg Injection

Nausea
Diarrhoea
Decreased platelet count
Fatigue
Vomiting
Headache
Abdominal pain
Dizziness
Skin rash
Myalgia
Pain at the site of injection
Injection site reactions

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Inonza 1 mg Injection work?

Inonza 1 mg Injection contains Inotuzumab Ozogamicin, which works by inhibiting the DNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Can pregnant women take Inonza 1 mg Injection?

Inonza 1 mg Injection is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman must have a negative pregnancy test before starting treatment with this medicine. Using effective birth control methods to prevent pregnancy while taking this medicine is better.

Drug-Drug Interactions Checker List

CLOZAPINE
CITALOPRAM
ESCITALOPRAM
NATALIZUMAB
SAQUINAVIR
EFAVIRENZ
HALOPERIDOL
DROPERIDOL
ADALIMUMAB
INFLIXIMAB

Special Advise

A blood test, such as LFT and RFT, should be performed to check for liver/kidney function.
Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).
An ECG and ECHO should be done in patients taking Inonza 1 mg Injection to check for any signs of cardiac problems.

Disease/Condition Glossary

Acute Lymphoblastic Leukemia (ALL): Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. ALL is a type of blood cancer that primarily affects your blood and bone marrow. It mainly targets the white blood cells, which can interfere with your body’s ability to combat infections. Symptoms may include fever, weight loss, abnormal blood cell count, bruising, and loss of appetite.