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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Intagesic MR Tablet 10's

Intagesic MR Tablet 10's belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). Intagesic MR Tablet 10's is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long term(chronic) in nature. Musculoskeletal pain can be caused due to soft tissues (muscle, tendon, and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Intagesic MR Tablet 10's is a fixed-dose combination composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Intagesic MR Tablet 10's can be taken with or after the meal. To avoid stomach upset Intagesic MR Tablet 10's can be taken with food or milk. It should be swallowed whole with a glass of water. Do not take Intagesic MR Tablet 10's if your pain lasts for more than ten days or fever lasting for more than three days. Do not take a double dose if you missed one dose. Like all medicines, Intagesic MR Tablet 10's may cause side effects, although not everybody gets them. Most of the side effects of Intagesic MR Tablet 10's are drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. In case of any discomfort, speak with your doctor. 

Do not take Intagesic MR Tablet 10's if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Intagesic MR Tablet 10's may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Intagesic MR Tablet 10's

Musculoskeletal pain.

Directions for Use

Take Intagesic MR Tablet 10's as advised by your doctor. Preferably take it with a light meal. Swallow it as a whole, do not chew or crush it.

Medicinal Benefits

Intagesic MR Tablet 10's is composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Intagesic MR Tablet 10's

  • Drowsiness
  • Constipation
  • Diarrhoea
  • Stomach upset
  • Slight discolouration of urine
  • Ringing or buzzing sounds in the ears

Drug Warnings

Intake of Intagesic MR Tablet 10's should be avoided in liver disease (like jaundice) and cardiovascular disease (like coronary heart disease). Contact your doctor if you have signs of liver disease like feeling exhausted, dark urine, not feeling hungry, stomach pain or upset, light coloured stools or yellow skin/eyes. After taking if you have possible allergic symptoms like difficulty in breathing, difficulty in swallowing, lips/face/throat swelling, chest tightness, or skin rash, contact the doctor immediately. Ensure your doctor is aware if you are pregnant or planning to get pregnant, breastfeeding, allergic to Intagesic MR Tablet 10's or any other painkillers like aspirin, the problem of stomach ulcer or gastric bleeding, or taking any other OTC multivitamins, multi-minerals supplements.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ChlorzoxazoneMorphine
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Intagesic MR Tablet:
Co-administration of Intagesic MR Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Intagesic MR Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Intagesic MR Tablet:
Using Morphine together with Intagesic MR Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Intagesic MR Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Intagesic MR Tablet:
Taking Tapentadol with Intagesic MR Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Intagesic MR Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
DiclofenacMethotrexate
Severe
How does the drug interact with Intagesic MR Tablet:
Co-administration of methotrexate with Intagesic MR Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Intagesic MR Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with Intagesic MR Tablet:
Taking Intagesic MR Tablet with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Intagesic MR Tablet and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacKetoconazole
Severe
How does the drug interact with Intagesic MR Tablet:
Coadministration of Intagesic MR Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Intagesic MR Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Intagesic MR Tablet:
Co-administration of Intagesic MR Tablet and Ketorolac can increase the risk of side effects.

How to manage the interaction:
Co-administration of Intagesic MR Tablet and Ketorolac can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacSirolimus
Severe
How does the drug interact with Intagesic MR Tablet:
Co-administration of Intagesic MR Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Intagesic MR Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Intagesic MR Tablet:
Co-administration of Intagesic MR Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Intagesic MR Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacSulindac
Severe
How does the drug interact with Intagesic MR Tablet:
Co-administration of Intagesic MR Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Intagesic MR Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Intagesic MR Tablet 10's is commonly prescribed for relieving pain in both acute and chronic conditions and in cases of fever. Do not take the drug beyond its suggested dose and frequency.
  • Avoid driving while consuming Intagesic MR Tablet 10's as it can cause dizziness in some individuals and hamper your focus and reflexes.
  • Avoid concomitant consumption of drugs containing the same chemicals as Intagesic MR Tablet 10's as it can lead to overdosage and unwanted side effects.
  • Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Intagesic MR Tablet 10's.
  • Avoid consuming alcohol while you are on Intagesic MR Tablet 10's.

Habit Forming

No

Therapeutic Class

ANALGESICS

Intagesic MR Tablet 10's Substitute

Substitutes safety advice
  • Powergesic Tablet 10's

    by Others

    13.41per tablet
  • Lobak Tablet 10's

    by Others

    7.88per tablet
  • Dan MR Tablet 10's

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    4.73per tablet
  • Alde Plus CX Tablet 10's

    by AYUR

    21.60per tablet
  • Dolozox-MR Neo Tablet 10's

    by Others

    5.90per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LISINOPRIL
  • HYDROCHLOROTHIAZIDE
  • RIVAROXABAN
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE
  • PREDNISONE

Special Advise

  • Intagesic MR Tablet 10's is prescribed for relief from muscle pain and spasms.
  • It can cause drowsiness and hence activities involving focus and attention like driving must be avoided while on this medication.
  • Concomitant usage of alcohol with this medicine increase the risk of damage to liver and other side effects and hence alcohol consumption should be avoided while consuming this medication
  • Avoid simultaneous consumption of other painkillers or cough and cold medicines with this Intagesic MR Tablet 10's as it may lead to overdose.

Disease/Condition Glossary

Musculoskeletal pain is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports related injury) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal

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