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Written By ,
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Isordil-10 Tablet

Isordil-10 Tablet belongs to the class of blood pressure-lowering medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) or heart failure. Angina pectoris (angina) is chest pain occurring due to reduced blood flow to the heart (coronary artery disease). It occurs when the blood vessels supplying the heart are blocked or narrowed.

Isordil-10 Tablet contains ‘isosorbide dinitrate’ which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients. 

Take Isordil-10 Tablet as prescribed. Your doctor will advise you on how often you take Isordil-10 Tablet based on your medical condition. The common side-effects of Isordil-10 Tablet are headache (during initial days of therapy) and flushing (reddening of the skin, especially the face). These side effects usually disappear without requiring medical attention. However, consult your doctor immediately if these effects persist or worsen.

Do not take it if you are allergic to ‘isosorbide dinitrate’ or any ingredients of it. Do not use in patients with severe heart failure, severe hypotension (low blood pressure), bleeding in the brain, severe dehydration, heart valve problems, progressive heart failure due to chronic lung disease, severe anemia (low levels of iron), and severe hypoxemia (low levels of oxygen in the blood). Inform your doctor if you have an underactive thyroid gland, glaucoma (an eye condition), or head injury. Inform your doctor if you are taking other prescription or non-prescription medicines, especially medicines used to treat erectile dysfunction in men. Isordil-10 Tablet contains lactose, so inform your doctor if you have an intolerance to some sugars. Also, inform your doctor if you are pregnant or breastfeeding.

Uses of Isordil-10 Tablet

Angina (heart related chest pain)

Directions for Use

Take Isordil-10 Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Medicinal Benefits

Isordil-10 Tablet contains ‘isosorbide dinitrate’ which is a ‘nitrate’ and a vasodilator. It acts by dilating and relaxing the constricted blood vessels due to increased blood pressure (hypertension). This effect helps in improving the blood and oxygen supply to the heart, thus decreasing the risk of angina or heart-related chest pain. Thus, Isordil-10 Tablet prevents the risk of chest pain in heart conditions like coronary artery disease. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Isordil-10 Tablet

  • Headache
  • Flushing (redness of the skin, especially the face)
  • Low blood pressure
  • Dizziness

Drug Warnings

Do not take Isordil-10 Tablet if you are allergic to ‘isosorbide dinitrate’ or its contents. Do not take it if you have severe low blood pressure, bleeding or increased pressure in the brain, severe dehydration, heart valve problems, inflammation of the heart wall, high blood pressure due to long-term lung disease, and severe anemia. Before taking Isordil-10 Tablet , inform your doctor if you have glaucoma (increased pressure in the eye), glucose 6 phosphate dehydrogenase deficiency (a type of anemia), underactive thyroid (hypothyroidism), kidney or liver problems, head injury, hypothermia (low body temperature), or intolerance to some sugars. This medicine should not be used with medicines used for erectile dysfunction like sildenafil or tadalafil. Inform your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
Isosorbide dinitrateRiociguat
Critical

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Avanafil with Isordil-10 Tablet can cause low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Riociguat with Isordil-10 Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Tadalafil with Isordil-10 Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Isordil-10 Tablet:
Coadministration of Isordil-10 Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateErgotamine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet together with ergotamine can increase the effects of ergotamine.

How to manage the interaction:
Although taking Isordil-10 Tablet and ergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Isordil-10 Tablet:
Combining Bupivacaine with Isordil-10 Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isordil-10 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
Isosorbide dinitrateSodium nitrite
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Isordil-10 Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateChloroprocaine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat plenty of fresh fruits and vegetables. Opt for whole grains rather than refined or polished grains. Choose lean proteins, such as skinless chicken and fish. Opt for non-fat or low-fat dairy products.
  • Do not take food containing high levels of sodium (salt).
  • Drink plenty of fluids to prevent dehydration. 
  • Maintain a normal weight. Shed excess weight by exercising regularly for at least 30 min a day.
  • Manage stress.
  • Limit alcohol intake and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Isordil-10 Tablet Substitute

Substitutes safety advice
  • Sorbitrate 10 mg Tablet 50's

    by Others

    0.81per tablet
  • Ismotag 10mg Tablet

    by Others

    0.73per tablet
  • Sorbitrate 10 mg Tablet 40's

    by AYUR

    1.01per tablet
  • Vasodil 10 mg Tablet 10's

    by Others

    1.71per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TADALAFIL
  • SILDENAFIL
  • VARDENAFIL
  • AVANAFIL
  • RIOCIGAUT
  • NOREPINEPHRINE

Special Advise

  • Isordil-10 Tablet may cause orthostatic hypotension (low blood pressure on standing). So, do no rise up quickly from a sitting or lying position suddenly. 
  • You may develop tolerance to Isordil-10 Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Keep all appointments. Your doctor will monitor your condition during the follow-up visits while taking this medication. 

Disease/Condition Glossary

Angina pectoris: It is the medical term for heart-related chest pain. It occurs when there is a reduction in blood supply to the heart due to the blockage of one or more arteries (coronary heart disease). Patients with angina often explain chest pain as squeezing, tightening, or pressure in the chest. Other symptoms can be dizziness, sweating, heartburn, and difficulty breathing.

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