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₹27984*
MRP ₹31800
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₹27984*
MRP ₹31800
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Whats That
About Itolizac 100 mg Injection
Itolizac 100 mg Injection belongs to the class of 'immunomodulators', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Itolizac 100 mg Injection may also be used to treat autoimmune conditions like rheumatoid arthritis and multiple sclerosis. Itolizac 100 mg Injection is currently being used and trialled to treat cytokine storm (excessive immune response) in COVID-19 (Corona Virus Disease-19) patients.
Itolizac 100 mg Injection consists of 'Itolizumab' that is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody (that serve as a substitute antibody). It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Itolizac 100 mg Injection is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response in the lungs of a COVID-19 infected person.
Your doctor will decide the dose and duration based on the medical condition. Common side effects of Itolizac 100 mg Injection include pain and swelling at the injection site, upper respiratory tract infection, fever, itching, dizziness, and diarrhoea. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.
Before starting Itolizac 100 mg Injection, inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, weak immune system (HIV), tuberculosis, hepatitis B, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Itolizac 100 mg Injection. Itolizac 100 mg Injection may cause dizziness, so drive only if you are alert and focused. Itolizac 100 mg Injection should not be given to children and adolescents under 18 years of age as safety has not been established. Avoid consuming alcohol along with Itolizac 100 mg Injection as it could lead to increased dizziness.
Uses of Itolizac 100 mg Injection
Directions for Use
Medicinal Benefits
Itolizac 100 mg Injection treats inflammation in patients with psoriasis and rheumatoid arthritis. It contains 'Itolizumab,' which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Itolizac 100 mg Injection is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is being used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19-infected person.
Storage
Drug Warnings
Inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), tuberculosis, hepatitis B, C, and active infections before starting Itolizac 100 mg Injection. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Itolizac 100 mg Injection to prevent any serious consequences. Itolizac 100 mg Injection may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Itolizac 100 mg Injection as it could lead to increased dizziness. Itolizac 100 mg Injection is not recommended in children and adolescents younger than 18 years of age as safety and efficacy is not established. Store Itolizac 100 mg Injection at temperatures of 2°C to 8°C. Do not freeze the vial.
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Itolizac 100 mg Injection contains Itolizumab, an immunomodulator. It reduces the synthesis of pro-inflammatory markers called cytokines. Thus, it helps in decreasing inflammation in various diseases like psoriasis, rheumatoid arthritis, and multiple sclerosis.
When a person is infected with the coronavirus, his/her immune system responds in such a way that it sends useful immune chemicals to the affected areas of the lungs to fight the infection. However, in some people, this release of immune chemicals is overactive, resulting in a cytokine storm, an excessive immune response in the lungs. This can further lead to severe breathing complications in an infected person. Itolizac 100 mg Injection reduces this cytokine storm and further prevents the inflammation and damage in the lungs of a COVID-19 infected person.
Itolizac 100 mg Injection is currently being used to decrease the negative outcome of the cytokine storm in critically, severely and moderately ill COVID-19 patients.
Itolizac 100 mg Injection is not recommended for every person infected with the coronavirus. Itolizac 100 mg Injection is only prescribed by doctors in patients with severe and critical COVID infection.
Itolizac 100 mg Injection is to be carefully administered with caution in patients under doctor's supervision only. The safety of Itolizac 100 mg Injection is not yet evaluated in conditions like neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), AIDS, tuberculosis, hepatitis B and C.
Even if there is no improvement after administering Itolizac 100 mg Injection, your doctor may suggest an alternate course. Please note that Itolizac 100 mg Injection does not reverse the damage caused due to coronavirus infection, but it will further prevent the inflammation of the lungs. It is also advised to medically examine for other lung and heart related dysfunctions even the patient suffers breathlessness after Itolizac 100 mg Injection administration.
It is not recommended to get live attenuated vaccines while being treated with Itolizac 100 mg Injection. This may lead to serious conditions. Please consult a doctor before you start Itolizac 100 mg Injection if you are undergoing any vaccinations.
Special Advise
Disease/Condition Glossary
Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. These red patches can commonly appear on the scalp, elbows, knees, and lower back. Psoriasis is a noncontagious (not spread by contact), chronic immune condition with no cure. It can be mild, moderate, and severe based on the patches coverage on the skin.
Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.
COVID-19: It is a disease caused by SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2). It mainly affects the respiratory system and is spread through droplets generated when an infected person coughs, sneezes, or exhales. Common symptoms include fever, dry cough, tiredness, body aches, sore throat, loss of taste and smell, and conjunctivitis. With the severity of the disease, symptoms like dropping oxygen saturation levels, shortness of breath, chest pain, high fever, and severe weakness are also noticed. The coronavirus can further lead to complications like pneumonia, respiratory failure, heart problems, liver problems, septic shock, and death.
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