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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ITRACONAZOLE-400MG

Manufacturer/Marketer :

Lifestar Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Itragreat-400Mg Sr Tablet

Itragreat-400Mg Sr Tablet belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itragreat-400Mg Sr Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Itragreat-400Mg Sr Tablet as prescribed. Your doctor will advise you on how often you take Itragreat-400Mg Sr Tablet based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itragreat-400Mg Sr Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itragreat-400Mg Sr Tablet or any other medicines, please tell your doctor. Itragreat-400Mg Sr Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itragreat-400Mg Sr Tablet. Do not take Itragreat-400Mg Sr Tablet if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itragreat-400Mg Sr Tablet. Avoid taking fentanyl (a strong opioid narcotic medicine) with Itragreat-400Mg Sr Tablet as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itragreat-400Mg Sr Tablet and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itragreat-400Mg Sr Tablet

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itragreat-400Mg Sr Tablet with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Itragreat-400Mg Sr Tablet is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Itragreat-400Mg Sr Tablet inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Itragreat-400Mg Sr Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Drug Warnings

If you are known to be allergic to Itragreat-400Mg Sr Tablet or any other medicines, please tell your doctor. Itragreat-400Mg Sr Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itragreat-400Mg Sr Tablet. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itragreat-400Mg Sr Tablet, as it may cause severe breathing problems and can even lead to death. Do not take Itragreat-400Mg Sr Tablet if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itragreat-400Mg Sr Tablet and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itragreat-400Mg Sr Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Itragreat-400Mg Sr Tablet:
The blood levels and effects of Ranolazine may be greatly increased when it is used with Itragreat-400Mg Sr Tablet.

How to manage the interaction:
Although Ranolazine and Itragreat-400Mg Sr Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itragreat-400Mg Sr Tablet:
Co-administartion of avanafil and Itragreat-400Mg Sr Tablet may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Itragreat-400Mg Sr Tablet may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itragreat-400Mg Sr Tablet:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itragreat-400Mg Sr Tablet along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itragreat-400Mg Sr Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Itragreat-400Mg Sr Tablet:
Alprazolam's blood levels may be significantly raised when combined with Itragreat-400Mg Sr Tablet.

How to manage the interaction:
Although combining Alprazolam and Itragreat-400Mg Sr Tablet may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleTriazolam
Critical
How does the drug interact with Itragreat-400Mg Sr Tablet:
Co-administration of Triazolam and Itragreat-400Mg Sr Tablet may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Itragreat-400Mg Sr Tablet may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itragreat-400Mg Sr Tablet:
Co-administration of Methylergometrine and Itragreat-400Mg Sr Tablet may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Itragreat-400Mg Sr Tablet may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Itragreat-400Mg Sr Tablet:
The blood level of Cisapride may be significantly raised by combining Cisapride with Itragreat-400Mg Sr Tablet.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Itragreat-400Mg Sr Tablet are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itragreat-400Mg Sr Tablet:
The blood levels and effects of nisoldipine may be greatly increased when used with Itragreat-400Mg Sr Tablet.

How to manage the interaction:
Nisoldipine and Itragreat-400Mg Sr Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itragreat-400Mg Sr Tablet:
Coadministration of Itragreat-400Mg Sr Tablet with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itragreat-400Mg Sr Tablet with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Itragreat-400Mg Sr Tablet:
Coadministration of colchicine with Itragreat-400Mg Sr Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Itragreat-400Mg Sr Tablet can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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ITRACONAZOLE-400MG-SRGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-400MG-SRGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itragreat-400Mg Sr Tablet may impair the absorption of Itragreat-400Mg Sr Tablet, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itragreat-400Mg Sr Tablet.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itragreat-400Mg Sr Tablet Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Itragreat-400Mg Sr Tablet with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itragreat-400Mg Sr Tablet with other medicines.

No, Itragreat-400Mg Sr Tablet is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itragreat-400Mg Sr Tablet and after 2 months of stopping treatment with Itragreat-400Mg Sr Tablet. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itragreat-400Mg Sr Tablet.

Itragreat-400Mg Sr Tablet may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itragreat-400Mg Sr Tablet to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itragreat-400Mg Sr Tablet and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itragreat-400Mg Sr Tablet as co-administration of these medicines at the same time may reduce the effectiveness of Itragreat-400Mg Sr Tablet because antacids decrease the absorption and blood levels of Itragreat-400Mg Sr Tablet. However, please consult a doctor before taking other medicines with Itragreat-400Mg Sr Tablet.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itragreat-400Mg Sr Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Itragreat-400Mg Sr Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itragreat-400Mg Sr Tablet, please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Itragreat-400Mg Sr Tablet to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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