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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ITRACONAZOLE-50MG

Manufacturer/Marketer :

Dhamus Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Itramus-SB 50 Capsule

Itramus-SB 50 Capsule belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itramus-SB 50 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Itramus-SB 50 Capsule as prescribed. Your doctor will advise you on how often you take Itramus-SB 50 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itramus-SB 50 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itramus-SB 50 Capsule or any other medicines, please tell your doctor. Itramus-SB 50 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itramus-SB 50 Capsule . Do not take Itramus-SB 50 Capsule if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itramus-SB 50 Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Itramus-SB 50 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itramus-SB 50 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itramus-SB 50 Capsule

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itramus-SB 50 Capsule with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Itramus-SB 50 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Itramus-SB 50 Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Itramus-SB 50 Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Itramus-SB 50 Capsule or any other medicines, please tell your doctor. Itramus-SB 50 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itramus-SB 50 Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itramus-SB 50 Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Itramus-SB 50 Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itramus-SB 50 Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itramus-SB 50 Capsule .

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
ItraconazoleAvanafil
Critical

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
How does the drug interact with Itramus-SB 50 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itramus-SB 50 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itramus-SB 50 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleAvanafil
Critical
How does the drug interact with Itramus-SB 50 Capsule:
Co-administartion of avanafil and Itramus-SB 50 Capsule may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Itramus-SB 50 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itramus-SB 50 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Itramus-SB 50 Capsule.

How to manage the interaction:
Nisoldipine and Itramus-SB 50 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleTolvaptan
Critical
How does the drug interact with Itramus-SB 50 Capsule:
Co-administration of Tolvaptan and Itramus-SB 50 Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itramus-SB 50 Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleSimvastatin
Critical
How does the drug interact with Itramus-SB 50 Capsule:
Simvastatin's blood levels and effects may be greatly increased when combined with Itramus-SB 50 Capsule.

How to manage the interaction:
Simvastatin and Itramus-SB 50 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with Itramus-SB 50 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Itramus-SB 50 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Itramus-SB 50 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleTicagrelor
Critical
How does the drug interact with Itramus-SB 50 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Itramus-SB 50 Capsule.

How to manage the interaction:
Itramus-SB 50 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleCisapride
Critical
How does the drug interact with Itramus-SB 50 Capsule:
The blood level of Cisapride may be significantly raised by combining Cisapride with Itramus-SB 50 Capsule.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Itramus-SB 50 Capsule are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleSilodosin
Critical
How does the drug interact with Itramus-SB 50 Capsule:
Coadministration of Itramus-SB 50 Capsule with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itramus-SB 50 Capsule with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleColchicine
Critical
How does the drug interact with Itramus-SB 50 Capsule:
Coadministration of colchicine with Itramus-SB 50 Capsule may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Itramus-SB 50 Capsule can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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ITRACONAZOLE-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itramus-SB 50 Capsule may impair the absorption of Itramus-SB 50 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itramus-SB 50 Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itramus-SB 50 Capsule Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Itramus-SB 50 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itramus-SB 50 Capsule with other medicines.

No, Itramus-SB 50 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itramus-SB 50 Capsule and after 2 months of stopping treatment with Itramus-SB 50 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itramus-SB 50 Capsule .

Itramus-SB 50 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itramus-SB 50 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itramus-SB 50 Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itramus-SB 50 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Itramus-SB 50 Capsule because antacids decrease the absorption and blood levels of Itramus-SB 50 Capsule . However, please consult a doctor before taking other medicines with Itramus-SB 50 Capsule .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itramus-SB 50 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Itramus-SB 50 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itramus-SB 50 Capsule , please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Itramus-SB 50 Capsule to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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