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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ITRACONAZOLE-100MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Itratuf Capsule

Itratuf Capsule belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itratuf Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Itratuf Capsule as prescribed. Your doctor will advise you on how often you take Itratuf Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itratuf Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itratuf Capsule or any other medicines, please tell your doctor. Itratuf Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itratuf Capsule . Do not take Itratuf Capsule if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itratuf Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Itratuf Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itratuf Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itratuf Capsule

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itratuf Capsule with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Itratuf Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Itratuf Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Itratuf Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Itratuf Capsule or any other medicines, please tell your doctor. Itratuf Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itratuf Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itratuf Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Itratuf Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itratuf Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itratuf Capsule .

Drug-Drug Interactions

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ItraconazoleAlprazolam
Critical
ItraconazoleNisoldipine
Critical

Drug-Drug Interactions

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ItraconazoleAlprazolam
Critical
How does the drug interact with Itratuf Capsule:
Alprazolam's blood levels may be significantly raised when combined with Itratuf Capsule.

How to manage the interaction:
Although combining Alprazolam and Itratuf Capsule may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itratuf Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Itratuf Capsule.

How to manage the interaction:
Nisoldipine and Itratuf Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Itratuf Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itratuf Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itratuf Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleColchicine
Critical
How does the drug interact with Itratuf Capsule:
Coadministration of colchicine with Itratuf Capsule may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Itratuf Capsule can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleTriazolam
Critical
How does the drug interact with Itratuf Capsule:
Co-administration of Triazolam and Itratuf Capsule may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Itratuf Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleMethylergometrine
Critical
How does the drug interact with Itratuf Capsule:
Co-administration of Methylergometrine and Itratuf Capsule may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Itratuf Capsule may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
ItraconazoleAvanafil
Critical
How does the drug interact with Itratuf Capsule:
Co-administartion of avanafil and Itratuf Capsule may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Itratuf Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleEplerenone
Critical
How does the drug interact with Itratuf Capsule:
The blood levels and effects of eplerenone may be greatly increased when combined with Itratuf Capsule.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Itratuf Capsule, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleSolifenacin
Critical
How does the drug interact with Itratuf Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with Itratuf Capsule.

How to manage the interaction:
Solifenacin and Itratuf Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
ItraconazoleRanolazine
Critical
How does the drug interact with Itratuf Capsule:
The blood levels and effects of Ranolazine may be greatly increased when it is used with Itratuf Capsule.

How to manage the interaction:
Although Ranolazine and Itratuf Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itratuf Capsule may impair the absorption of Itratuf Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itratuf Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itratuf Capsule Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Itratuf Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itratuf Capsule with other medicines.

No, Itratuf Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itratuf Capsule and after 2 months of stopping treatment with Itratuf Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itratuf Capsule .

Itratuf Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itratuf Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itratuf Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itratuf Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Itratuf Capsule because antacids decrease the absorption and blood levels of Itratuf Capsule . However, please consult a doctor before taking other medicines with Itratuf Capsule .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itratuf Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Itratuf Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itratuf Capsule , please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Itratuf Capsule to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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