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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Jollimex-50 Capsule 10's

Jollimex-50 Capsule 10's belongs to a class of medicines called antiarrhythmics used to treat life-threatening arrhythmias (irregular heartbeats) such as ventricular arrhythmia. Arrhythmia is a condition in which your heart beats irregularly, too fast, or too slow.

Jollimex-50 Capsule 10's contains Mexiletine, which works by reducing the sensitivity of heart muscle cells to electrical impulses. Thus, it slows down electrical conduction in the heart muscle. Thereby, it helps to restore regular heart rhythm.

Take Jollimex-50 Capsule 10's as prescribed. You are advised to take Jollimex-50 Capsule 10's for as long as your doctor has recommended it based on your medical condition. In some cases, Jollimex-50 Capsule 10's may cause common side effects such as stomach pain, insomnia (difficulty sleeping), dyspepsia (indigestion), dizziness, tremors (involuntary shaking), chest discomfort or headache. Most of these side effects of Jollimex-50 Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Mexiletine, local anaesthetics, or other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Jollimex-50 Capsule 10's. Jollimex-50 Capsule 10's is not recommended for children and adolescents below 18 years of age. Avoid alcohol consumption with Jollimex-50 Capsule 10's as it may worsen dizziness or drowsiness. Jollimex-50 Capsule 10's may cause dizziness, drowsiness or blurred vision in some people. Therefore, drive only if you are alert after taking Jollimex-50 Capsule 10's. 

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Non returnable*
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Composition

MEXILETINE-50MG

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Jollimex-50 Capsule 10's

Ventricular arrhythmia (irregular heartbeats)

Medicinal Benefits

Jollimex-50 Capsule 10's contains Mexiletine used to treat life-threatening arrhythmias (irregular heartbeats) such as ventricular arrhythmia. It decreases the sensitivity of heart muscle cells to electrical impulses. Thus, it slows down electrical conduction in the heart muscle. Thereby, it helps restore regular heart rhythm. 

Side Effects of Jollimex-50 Capsule 10's

  • Stomach pain
  • Insomnia (difficulty sleeping)
  • Dyspepsia (indigestion)
  • Dizziness
  • Tremor (involuntary shaking)
  • Chest discomfort
  • Headache 

Directions for Use

Take this medicine as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Mexiletine, any local anaesthetics or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Jollimex-50 Capsule 10's. Jollimex-50 Capsule 10's is not recommended for children and adolescents below 18 years of age. Avoid intake of alcohol with Jollimex-50 Capsule 10's as it may worsen dizziness or drowsiness. Jollimex-50 Capsule 10's may cause dizziness, drowsiness or blurred vision in some people. Therefore, drive only if you are alert after taking Jollimex-50 Capsule 10's. Inform your doctor if you have a genetic problem with an enzyme in your body called CYP2D6 which breaks down (metabolizes) certain medicines in your body too slowly, because a different dose may be applicable to you. If you start to smoke or quit smoking while taking Jollimex-50 Capsule 10's, inform your doctor as smoking impacts the Mexiletine blood levels, and your dose may need to be adjusted accordingly.

Therapeutic Class

ANTIARRHYTHMICS

Drug-Drug Interactions

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MexiletineArbutamine
Critical
MexiletineAminophylline
Severe

Drug-Drug Interactions

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MexiletineArbutamine
Critical
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of Arbutamine with Jollimex-50 Capsule 10's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jollimex-50 Capsule 10's with Arbutamine is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience chest tightness, blurred vision or nausea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineAminophylline
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of aminophylline with Jollimex-50 Capsule 10's can increase the blood levels of aminophylline and increase the risk of serious side effects.

How to manage the interaction:
Taking Aminophylline with Jollimex-50 Capsule 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineIohexol
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of iohexol with Jollimex-50 Capsule 10's can increase the risk or severity of fits. The risk increases in patients with a history of fits, head and brain trauma, or undergoing alcohol or drug withdrawal.

How to manage the interaction:
Although taking iohexol and Jollimex-50 Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as pale, headache, rapid heart rate, shortness of breath, lightheadedness; or fatigue, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineRasagiline
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of rasagiline with Jollimex-50 Capsule 10's can increase blood levels of rasagiline.

How to manage the interaction:
Taking rasagiline with Jollimex-50 Capsule 10's can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as drowsiness, dizziness, lightheadedness, blood pressure changes, nausea, vomiting, hallucinations, or abnormal behaviour, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineChlorpheniramine
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of chlorpheniramine with Jollimex-50 Capsule 10's may cause the side effects of Jollimex-50 Capsule 10's.

How to manage the interaction:
Although taking chlorpheniramine and Jollimex-50 Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MexiletineIopamidol
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of iopamidol with Jollimex-50 Capsule 10's can increase the risk or severity of fits. The risk increases in the elderly, patients undergoing alcohol or drug withdrawal, who have a history of fits or head trauma.

How to manage the interaction:
Although taking iopamidol and Jollimex-50 Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as pale, headache, rapid heart rate, shortness of breath, lightheadedness; or fatigue, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineDroperidol
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of droperidol with Jollimex-50 Capsule 10's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although taking droperidol and Jollimex-50 Capsule 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, vomiting, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineIomeprol
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of iomeprol with Jollimex-50 Capsule 10's can increase the risk or severity of fits. The risk increases in the elderly, patients undergoing alcohol or drug withdrawal, who have a history of fits or head trauma.

How to manage the interaction:
Although taking iomeprol and Jollimex-50 Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as pale, headache, rapid heart rate, shortness of breath, lightheadedness; or fatigue, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineTheophylline
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Co-administration of theophylline with Jollimex-50 Capsule 10's can increase the effect of Jollimex-50 Capsule 10's. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking theophylline with Jollimex-50 Capsule 10's can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, diarrhea, loss of appetite, headache, tremor, confusion, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MexiletineBupivacaine
Severe
How does the drug interact with Jollimex-50 Capsule 10's:
Taking Jollimex-50 Capsule 10's with Bupivacaine may cause serious side effects including methemoglobinemia, a serious blood disorder in which too little oxygen is delivered to your cells and heart problems.

How to manage the interaction:
Although taking bupivacaine and Jollimex-50 Capsule 10's together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you develop pale, grey, or blue-coloured skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, Jerking movements of the arms and legs, Loss of consciousness, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMIODARONE
  • VERAPAMIL
  • PROPRANOLOL
  • PHENYTOIN
  • FLUVOXAMINE
  • OMEPRAZOLE
  • MORPHINE
  • ATROPINE
  • THEOPHYLLINE
  • METOCLOPRAMIDE
  • CIPROFLOXACIN
  • RIFAMPICIN
  • METFORMIN
  • WARFARIN
  • TIZANIDINE

Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise as it helps lower blood pressure and keeps blood vessels and the heart in good condition.
  • Quit smoking as smoking increases blood pressure and heart rate.
  • Eat a balanced and healthy diet that includes plenty of vegetables, fruits, and low-fat or fat-free products.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Arrhythmia (irregular heartbeat): It is a condition in which your heart beats irregularly, too fast, or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, and fast or slow heartbeat. 60 to 100 beats per minute is generally considered a normal heart rate.

Ventricular arrhythmia: It is a type of arrhythmia which begins in the ventricles (lower chambers of the heart). It causes irregular heartbeat and prevents circulation of oxygen-rich blood to the brain and body, and may result in cardiac arrest. This condition may be life-threatening and requires immediate medical attention.

Jollimex-50 Capsule 10's Substitute

Substitutes safety advice
  • Welhart 50 Capsule 10's

    27.23per tablet
  • Mexohar 50 mg Capsule 30's

    27.23per tablet
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