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Reviewed By Sureshvarma D , MPharma
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About Jonvir-ET Tablet

Jonvir-ET Tablet belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

You should take this medicine exactly as prescribed by the doctor. Jonvir-ET Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

It is not recommended to take Jonvir-ET Tablet if you are allergic to any contents of it. Before taking Jonvir-ET Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, Hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Jonvir-ET Tablet should not be given to children below 2 years of age. Jonvir-ET Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Jonvir-ET Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Jonvir-ET Tablet

Hiv infection.

Directions for Use

Swallow Jonvir-ET Tablet as a whole with water. Do not chew, crush or break it. Jonvir-ET Tablet is to be taken empty stomach.

Medicinal Benefits

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

It is not recommended to take Jonvir-ET Tablet if you are allergic to any contents of it. Before taking Jonvir-ET Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Jonvir-ET Tablet should not be given to children below 2 years of age. Jonvir-ET Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Jonvir-ET Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Jonvir-ET Tablet should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.

Drug-Drug Interactions

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EfavirenzRilpivirine
Critical
EfavirenzBepridil
Critical

Drug-Drug Interactions

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EfavirenzRilpivirine
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Rilpivirine with Jonvir-ET Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Jonvir-ET Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzBepridil
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Bepridil with Jonvir-ET Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Jonvir-ET Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
Using ziprasidone together with Jonvir-ET Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Jonvir-ET Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
Taking Jonvir-ET Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jonvir-ET Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
Taking Jonvir-ET Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jonvir-ET Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
Using carbamazepine together with Jonvir-ET Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Jonvir-ET Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Jonvir-ET Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Jonvir-ET Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Jonvir-ET Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jonvir-ET Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jonvir-ET Tablet:
Coadministration of Voriconazole with Jonvir-ET Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Jonvir-ET Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly. Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Eating a diet high in vegetables, fruits, whole grains, and legumes.
  • Choosing lean, low-fat sources of protein.
  • Limiting sweets, soft drinks, and foods with added sugar.
  • Including proteins, carbohydrates, and a little good fat in all meals and snacks.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Jonvir-ET Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

Jonvir-ET Tablet may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.

Jonvir-ET Tablet should not be stopped suddenly. Inform your doctor before stopping Jonvir-ET Tablet.

Jonvir-ET Tablet should be used with caution in liver diseases, kidney diseases, hypercholesterolemia, CNS disorders and lactic acidosis.

Drug-Drug Interactions Checker List

  • CISPLATIN
  • METHOTREXATE
  • TOBRAMYCIN
  • AZITHROMYCIN
  • CITALOPRAM
  • FLUCONAZOLE
  • GENTAMICIN
  • CIPROFLOXACIN
  • AMIODARONE
  • ASPIRIN

Special Advise

  • Do not stop taking Jonvir-ET Tablet without your doctor’s advice.
  • Monitor your liver function tests and kidney function tests regularly.

Disease/Condition Glossary

HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

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