Joxate-O Tablet 10's belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract (kidney and bladder). Joxate-O Tablet 10's helps relieve symptoms which may occur due to the infection such as painful urination, inability to control urine flow, and excessive urination at night. Urinary tract infections are caused by microbes such as bacteria and can affect the kidneys, bladder, and the tubes that run between them.

Joxate-O Tablet 10's is a combination of two drugs, namely: Ofloxacin (quinolone antibiotic) and Flavoxate (anti-spasmodic). Ofloxacin prevents the bacteria from repairing and reproducing themselves, thereby kills the bacteria. Flavoxate relaxes the muscles of the urinary bladder, thereby helps in preventing frequent urination, and excessive or uncontrolled urination. 
 
In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach upset, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Joxate-O Tablet 10's contains ofloxacin which might increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Consult your doctor before taking Joxate-O Tablet 10's if you are pregnant or breast-feeding. Joxate-O Tablet 10's may cause dizziness, so drive with caution. Joxate-O Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid or limit the intake of alcohol while taking Joxate-O Tablet 10's as it could lead to increased dizziness.

Joxate-O Tablet 10's belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract (kidney and bladder). Joxate-O Tablet 10's helps to relieve symptoms which may occur due to the infection such as painful urination, inability to control urine flow, and excessive urination at night. Joxate-O Tablet 10's is a combination of two drugs, namely: Ofloxacin (quinolone antibiotic) and Flavoxate (anti-spasmodic). Ofloxacin prevents the bacteria from repairing and reproducing themselves, thereby kills the bacteria. Flavoxate relaxes the muscles of the urinary bladder, thereby helps in preventing frequent urination, and excessive or uncontrolled urination.

• Nausea
• Vomiting
• Stomach upset
• Dizziness
• Headache

Do not take Joxate-O Tablet 10's if you are allergic to any of its contents; if you have gastrointestinal bleeding, obstruction in food passage, muscular inability to swallow, urinary retention, glaucoma, seizures or muscle weakness. Joxate-O Tablet 10's contains ofloxacin which might increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Talk to your doctor before taking Joxate-O Tablet 10's if you have mental illness, nervous, heart, kidney or liver problems. Consult your doctor before taking Joxate-O Tablet 10's if you are pregnant or breast-feeding. Joxate-O Tablet 10's may cause dizziness, so drive only if you are alert. Joxate-O Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Joxate-O Tablet 10's as it could lead to increased dizziness.

Drug-Drug Interactions: Joxate-O Tablet 10's may interact with anticonvulsant (topiramate, valproic acid), antihistamine (diphenhydramine, chlorpheniramine, cetirizine), anti-anxiety (alprazolam and duloxetine), pain killers (aspirin, ibuprofen, acetaminophen), anti-spasmodic (oxybutynin), anti-depressant (fluoxetine), antibiotic (azithromycin, sulfamethoxazole, trimethoprim, erythromycin), corticosteroid (dexamethasone), diuretic (furosemide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have urinary obstruction, gastrointestinal obstruction, glaucoma, colitis (inflammation of the colon), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), tendonitis (inflammation of tendons), and heart problems.

• TOPIRAMATE
• VALPROIC ACID
• DIPHENHYDRAMINE
• CHLORPHENIRAMINE
• CETIRIZINE
• ALPRAZOLAM
• DULOXETINE
• ASPIRIN
• IBUPROFEN
• ACETAMINOPHEN
• OXYBUTYNIN
• FLUOXETINE
• AZITHROMYCIN
• SULPHAMETHOXAZOLE+TRIMETHOPRIM
• ERYTHROMYCIN
• DEXAMETHASONE
• FUROSEMIDE

• Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
• Antibiotics can alter the useful bacteria in the stomach, which help indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
• Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
• Pelvic floor exercises would help treat bladder spasms.
• Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
• Drink 6-8 glasses of water every day.
• Do not hold in the urine for longer periods.
• Avoid drinking excess alcohol or caffeine.
• Maintain a healthy weight, exercise regularly.

Urinary tract infections (UTI): UTI is an infection in any part of the urinary system- the kidneys, bladder or urethra. A bladder infection may cause an increased urge to urinate, pelvic pain, pain during urination, and blood in the urine. A kidney infection may cause tenderness and pain in the back, fever, chills, nausea, and vomiting. The causes of UTI include a weak immune system, kidney stones, enlarged prostate, prolonged use of urinary catheters, diabetes, poor bathroom hygiene, sexual activity and age. Urinary tract infections are contagious and can spread to other body parts easily. Early diagnosis and treatment can help in preventing further complications.