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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Biophar Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Juvitine M Tablet

Juvitine M Tablet belongs to the class of medications called ‘anticonvulsants’ used to treat neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Juvitine M Tablet is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that works by increasing the levels of a chemical messenger (like serotonin and noradrenaline) in the brain required to regulate pain that travels through damaged nerves. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). 

Take this medicine as prescribed by your doctor. Juvitine M Tablet may cause side-effects such as drowsiness, nausea, constipation, headache, dry mouth, increased sweating, anorexia (loss of appetite) and hot sensation (burning pain). Inform your doctor if any of these side-effects persist.

Do not take Juvitine M Tablet if you are allergic to Duloxetine, Methylcobalamin, or any contents of it. Before taking Juvitine M Tablet , inform your doctor if you have liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. Inform your doctor if you are pregnant or breastfeeding before using Juvitine M Tablet . 

Uses of Juvitine M Tablet

Neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Juvitine M Tablet is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that increases serotonin levels and noradrenaline in the brain required for regulating pain through the damaged nerves. Methylcobalamin is a form of vitamin B12 that helps in rejuvenating and protecting damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). Together, Juvitine M Tablet effectively treats neuropathic pain, improve nerve conduction for proper nerve signal functioning in the body. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Juvitine M Tablet

  • Drowsiness
  • Nausea
  • Constipation
  • Headache
  • Dry mouth
  • Increased sweating
  • Anorexia (loss of appetite)
  • Hot sensation (burning pain)

Drug Warnings

Before taking Juvitine M Tablet , inform your doctor if you have taken any antidepressants within the last 14 days or any medications used to treat infections. Please consult your doctor before stopping the medicine as it may cause withdrawal symptoms such as dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. So, do not abruptly stop taking medicine even if your symptoms improve. It may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. Prolonged use of Juvitine M Tablet may decrease sodium level, affect blood pressure, and blood sugar level, so regular medical check-ups are required. Juvitine M Tablet may increase your bleeding risk, and worsen your glaucoma condition. Hence, if you experience any eye problem or a bleeding problem, consult a doctor. 

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Juvitine M Tablet Substitute

Substitutes safety advice
  • Dullix-M Tablet 10's

    by Others

    17.91per tablet
  • Duloba M-20 Tablet 10's

    by Others

    10.40per tablet
  • Duloxtivak-M Tablet

    by Others

    18.81per tablet
  • Duloctus M 20mg/750mcg Tablet

    by Others

    19.44per tablet
  • Lupex-Plus Tablet

    by Others

    27.00per tablet

FAQs

Juvitine M Tablet is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine increases the number of neurotransmitters like serotonin and noradrenaline in the brain that can regulate pain. On the other hand, methylcobalamin (vitamin B12) can protect the nerve cells from further damage. Thus, Juvitine M Tablet prevents nerve damage due to various conditions like injury or diabetic neuropathy and smooth conduction of nerve signal throughout the body.

Juvitine M Tablet should be taken either in the morning or evening. If you feel drowsy after taking Juvitine M Tablet , consider taking it in the evening. Also, it is recommended to take Juvitine M Tablet every day at the same time for the best results.

Juvitine M Tablet should not be used with antidepressants, especially antidepressants like monoamine oxidase (MAO) inhibitors (moclobemide, linezolid) as they cause serious side-effects. It is advised to wait at least 14 days after stopping MAO inhibitors before taking $namd also wait at least 5 days after stopping Juvitine M Tablet before taking any MAO inhibitors.

Seek medical attention immediately if you notice any depressive thoughts while using Juvitine M Tablet . Your doctor may change the dose or medicine to treat your condition.

Drug-Drug Interactions Checker List

  • MOCLOBEMIDE
  • PAROXETINE
  • FLUOXETINE
  • VENLAFAXINE
  • CLOMIPRAMINE
  • AMITRIPTYLINE
  • LINEZOLID
  • TRAMADOL
  • HYPERICUM PERFORATUM

Special Advise

  • Increased risk of suicidal thinking and behavioural change in children below 12 years, and young adults taking Juvitine M Tablet  for major depressive disorder (MDD) and other psychiatric disorders. Hence, the use of Juvitine M Tablet is not approved for use in pediatric patients.  
  • If you experience small increases in fasting blood glucose, HbA1c, and total cholesterol (TC) levels, immediately contact a doctor. 
  • Regular blood pressure monitoring is required while using Juvitine M Tablet . 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease, infection, or injury caused due to damaged sensory nerves. Pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. In normal condition, our body sends the pain signals when there is an injury, but in neuropathic pain, pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful). 

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