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  3. Kabilen 10 mg Tablet 1's

Kabilen 10 mg Tablet 1's, Pack of 1 TABLET
Kabilen 10 mg Tablet 1's, Pack of 1 TABLET
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Whats That

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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kabilen 10 mg Tablet

Kabilen 10 mg Tablet belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS where part of chromosome 5 is missing.
 
Kabilen 10 mg Tablet contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Kabilen 10 mg Tablet if you are pregnant or breastfeeding. Kabilen 10 mg Tablet may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Kabilen 10 mg Tablet must use effective contraception. Inform your doctor regarding your health condition and medications before taking Kabilen 10 mg Tablet to rule out any interactions.

Uses of Kabilen 10 mg Tablet

Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Kabilen 10 mg Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Kabilen 10 mg Tablet belongs to the group of medicines called immunomodulatory agents. Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Storage

Store in a cool and dry place away from sunlight
Side effects of Kabilen 10 mg Tablet
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not take Kabilen 10 mg Tablet if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Kabilen 10 mg Tablet if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Kabilen 10 mg Tablet if you are breastfeeding as it is not unknown if it passes into breastmilk. Kabilen 10 mg Tablet may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for use in children. Avoid consuming alcohol along with Kabilen 10 mg Tablet as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
LenalidomideRotavirus vaccine
Critical
LenalidomideAnakinra
Critical

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Administering the Rotavirus vaccine together with Kabilen 10 mg Tablet may increase the risk of infections.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Kabilen 10 mg Tablet. Do not stop using any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Taking anakinra with Kabilen 10 mg Tablet can increase the risk of negative side effects.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Combining the BCG vaccine with Kabilen 10 mg Tablet increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
When combining the Yellow fever vaccine with Kabilen 10 mg Tablet, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideConjugated Estrogens
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Coadministration of Kabilen 10 mg Tablet with Conjugated estrogens may increase the risk of developing unwanted blood clots.

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and conjugated estrogens, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, coughing up blood, blurred vision, swelling in an arm or leg, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomidePitavastatin
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Taking Kabilen 10 mg Tablet and Pitavastatin together can increase the risk of rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and pitavastatin, it can be taken if prescribed by a doctor. However, if you experience unexplained muscle pain, tenderness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideBaricitinib
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Coadministration of baricitinib and Kabilen 10 mg Tablet can raise your risk of developing serious infections.

How to manage the interaction:
Although there is an interaction between baricitinib and Kabilen 10 mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood while coughing, weight loss, red or irritated skin, body sores, and discomfort, consult a doctor. Do not discontinue any medications without consulting a doctor.
LenalidomideAtezolizumab
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Using Atezolizumab and Kabilen 10 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Atezolizumab and Kabilen 10 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Taking Kabilen 10 mg Tablet together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideGolimumab
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Taking Kabilen 10 mg Tablet and golimumab together may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and golimumab, it can be taken if prescribed by a doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Aug 20, 2024 | 1:09 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Kabilen 10 mg Tablet on your own. You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kabilen 10 mg Tablet.

No, it is not safe to father a child while taking Kabilen 10 mg Tablet. Kabilen 10 mg Tablet can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Kabilen 10 mg Tablet and for at least 4weeks after discontinuing Kabilen 10 mg Tablet, even if you have undergone a successful vasectomy. Male patients taking Kabilen 10 mg Tablet must not donate semen whilst taking Kabilen 10 mg Tablet and for 4weeks after discontinuing Kabilen 10 mg Tablet.

Patients taking Kabilen 10 mg Tablet must not donate blood during the treatment with Kabilen 10 mg Tablet and for 1month after discontinuation of Kabilen 10 mg Tablet as the donated blood might be given to pregnant women whose foetus should not be exposed to Kabilen 10 mg Tablet since it causes severe birth defects.

People with multiple myeloma taking Kabilen 10 mg Tablet may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Kabilen 10 mg Tablet for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Kabilen 10 mg Tablet might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Kabilen 10 mg Tablet.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Special Advise

  • Do not take Kabilen 10 mg Tablet if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking Kabilen 10 mg Tablet must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking Kabilen 10 mg Tablet and for 4weeks after discontinuing Kabilen 10 mg Tablet.
  • Kabilen 10 mg Tablet might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.
  • Kabilen 10 mg Tablet might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Kabilen 10 mg Tablet.
  • Kabilen 10 mg Tablet might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Kabilen 10 mg Tablet. Consult your doctor if you are diabetic.
  • Inform your doctor if you have any kidney dysfunction as Kabilen 10 mg Tablet might cause kidney problems.
  • Regular blood tests are advised before and during treatment with Kabilen 10 mg Tablet.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is the cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. Incase of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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