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  3. Kalomin 4.5MIU Injection 1's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Whats That

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Synonym :

COLISTIN

Manufacturer/Marketer :

Aequitas Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Kalomin 4.5MIU Injection 1's

Kalomin 4.5MIU Injection 1's belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Kalomin 4.5MIU Injection 1's contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Kalomin 4.5MIU Injection 1's destroys the bacteria and successfully treats the infection.

Kalomin 4.5MIU Injection 1's will be administered by a qualified healthcare professional. Sometimes, you may experience common side effects like injection site reactions, renal damage, visual disturbances, GI disturbances, dizziness, nausea, vomiting and muscle weakness. But these side effects are usually in the initial phase and resolve over time. However, if these side effects persist, let your doctor know.

Before receiving Kalomin 4.5MIU Injection 1's, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Kalomin 4.5MIU Injection 1's can cause blurred vision and dizziness in some people; if this occurs, do not drive or operate tools or machinery. It is recommended not to consume any alcoholic beverages while on treatment with this medicine.

Uses of Kalomin 4.5MIU Injection 1's

Bacterial infections

Directions for Use

Kalomin 4.5MIU Injection 1's will be administered by a qualified healthcare professional. Do not self-administer.

Medicinal Benefits

Kalomin 4.5MIU Injection 1's contains Colistimethate Sodium. Colistimethate Sodium, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Kalomin 4.5MIU Injection 1's kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

Storage

Keep Kalomin 4.5MIU Injection 1's out of the sight and reach of children.

Drug Warnings

If you are allergic to Kalomin 4.5MIU Injection 1's, please inform your physician. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding before receiving Kalomin 4.5MIU Injection 1's. Also, inform your doctor if you have chronic kidney disease, myasthenia gravis (muscle disorder), and porphyria (a blood disorder). Do not abruptly discontinue taking the prescription since this may result in antibiotic resistance, a condition in which bacteria develop resistance to antibiotics.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Kalomin 4.5MIU Injection:
Coadministration of Kalomin 4.5MIU Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Kalomin 4.5MIU Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
How does the drug interact with Kalomin 4.5MIU Injection:
Coadministration of Kalomin 4.5MIU Injection with Amikacin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Amikacin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Using Pancuronium with Kalomin 4.5MIU Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Coadministration of Rocuronium bromide with Kalomin 4.5MIU Injection may increase the side effects of Rocuronium bromide.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Rocuronium bromide, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Using Vecuronium with Kalomin 4.5MIU Injection can make Vecuronium more effective in therapy.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Vecuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Taking Human immunoglobulin with Kalomin 4.5MIU Injection, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Kalomin 4.5MIU Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kalomin 4.5MIU Injection:
Using Suxamethonium together with Kalomin 4.5MIU Injection may increase the effects of Suxamethonium.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Suxamethonium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash Paresthesia (tingling or pricking sensation) Dizziness Slurred speech Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Coadministration of Tobramycin with Kalomin 4.5MIU Injection can increase the blood levels and risk of Kalomin 4.5MIU Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Tobramycin, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Combining Kalomin 4.5MIU Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kalomin 4.5MIU Injection:
Combining Kalomin 4.5MIU Injection with Adefovir dipivoxil may decrease Kalomin 4.5MIU Injection's excretion rate, which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Kalomin 4.5MIU Injection and Adefovir dipivoxil, you can take these medicines together if prescribed by your doctor. However, if you experience any irregular urination, swelling, shortness of breath, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After taking the full course of Kalomin 4.5MIU Injection 1's, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking many calcium-enriched foods and drinks as it might affect the working of Kalomin 4.5MIU Injection 1's.
  • Avoid intake of alcoholic beverages with Kalomin 4.5MIU Injection 1's as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Kalomin 4.5MIU Injection 1's in fighting off infections.

Side Effects of Kalomin 4.5MIU Injection 1's

  • Superinfection (reinfection)
  • Renal damage
  • Visual disturbances
  • GI disturbances
  • Dizziness
  • Nausea
  • Vomiting
  • Confusion
  • Peripheral neuropathy
  • Respiratory insufficiency
  • Muscle weakness

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kalomin 4.5MIU Injection 1's contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Kalomin 4.5MIU Injection 1's destroys the bacteria and successfully treats the infection.

Kalomin 4.5MIU Injection 1's is contraindicated in people with Hypersensitivity to any component in Kalomin 4.5MIU Injection 1's. Besides this, it is also contraindicated to use in people with myasthenia gravis (muscle disorder).

Kalomin 4.5MIU Injection 1's contains Colistimethate Sodium. It is an antibiotic medication used when other drugs or therapy are ineffective. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Kalomin 4.5MIU Injection 1's kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

Do not use anti diarrhoeal until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea as it may help increase the number of good bacteria in the intestine, which aids indigestion.

After taking an antibiotic, you may need to wait up to three hours to eat or drink dairy products, including milk and butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.

Drug-Drug Interactions Checker List

  • CYCLOBENZAPRINE
  • METAXALONE
  • AMPHOTERICIN B
  • CAPREOMYCIN
  • VANCOMYCIN

Special Advise

  • Regular blood tests are required to monitor kidney functions while taking Kalomin 4.5MIU Injection 1's.
  • A Healthcare professional should always give a Kalomin 4.5MIU Injection 1's to a hospital. Never self-administer.

Disease/Condition Glossary

Bacterial infections: A bacterial infection occurs when harmful bacteria enter the body, multiply, and infect it. It may attack any region of the body and multiply swiftly. Fever, chills, and tiredness are common symptoms. Bacteria come in a variety of shapes, including spherical, rod, and spiral-shaped bacteria. Bacterial infections range in severity from simple ailments such as sore throats and ear infections to serious brain infections such as meningitis and encephalitis. A bacterial infection can infect anyone at any time. People with a weakened immune system or who are on immunosuppressive medications, on the other hand, are more vulnerable to bacterial infection.

Have a query?

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Alcohol

Caution

Limit alcohol consumption while on treatment with this medicine as it may worsen drowsiness, dizziness or sleepiness.

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Pregnancy

Caution

Kalomin 4.5MIU Injection 1's should not be used in pregnancy unless necessary. Hence, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Kalomin 4.5MIU Injection 1's.

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Breast Feeding

Caution

Kalomin 4.5MIU Injection 1's should not be used in nursing mothers unless necessary. So, inform your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing Kalomin 4.5MIU Injection 1's.

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Driving

Caution

You may have side effects like visual disturbances and dizziness after taking Kalomin 4.5MIU Injection 1's that may make you unfit to drive or operate machinery. Hence, do not drive or operate machinery until you are feeling well.

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Liver

Safe if prescribed

Inform your doctor before receiving Kalomin 4.5MIU Injection 1's if you have a liver impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Caution should be exercised while using Kalomin 4.5MIU Injection 1's in patients with severe kidney disease. Inform your doctor before receiving Kalomin 4.5MIU Injection 1's if you have a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

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