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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Consume Type :

ORAL

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Not Returnable

About Kelebek 300mg/1500mcg Tablet

Kelebek 300mg/1500mcg Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizures episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Kelebek 300mg/1500mcg Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, furtherly reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Kelebek 300mg/1500mcg Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Kelebek 300mg/1500mcg Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Kelebek 300mg/1500mcg Tablet. If you are a pregnant or breastfeeding mother, please consult your doctor before taking Kelebek 300mg/1500mcg Tablet. Kelebek 300mg/1500mcg Tablet causes drowsiness and dizziness, so drive only if you are alert. Kelebek 300mg/1500mcg Tablet should not be given to children under three years as safety and effectiveness have not been established. Avoid consuming alcohol along with Kelebek 300mg/1500mcg Tablet as it could lead to increased dizziness and sleepiness. 

Uses of Kelebek 300mg/1500mcg Tablet

Neuropathic pain and Epilepsy (fits).

Directions for Use

Take Kelebek 300mg/1500mcg Tablet with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Kelebek 300mg/1500mcg Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kelebek 300mg/1500mcg Tablet

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea 
  • Vomiting 

Drug Warnings

Inform your doctor before taking Kelebek 300mg/1500mcg Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Kelebek 300mg/1500mcg Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Kelebek 300mg/1500mcg Tablet. Consult your doctor immediately if you experience suicidal tendencies. Keep Kelebek 300mg/1500mcg Tablet away from direct sunlight. Do not store Kelebek 300mg/1500mcg Tablet above 25ºC and keep it away from direct sunlight.

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
GabapentinButorphanol
Severe

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Co-administration of Buprenorphine and Kelebek 300mg/1500mcg Tablet may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Kelebek 300mg/1500mcg Tablet and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinButorphanol
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Co-administration of Butorphanol and Kelebek 300mg/1500mcg Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Kelebek 300mg/1500mcg Tablet and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinKetamine
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Using Ketamine together with Kelebek 300mg/1500mcg Tablet may increase side effects.

How to manage the interaction:
Although taking Ketamine and Kelebek 300mg/1500mcg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinCodeine
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Combining Codeine with Kelebek 300mg/1500mcg Tablet can increase the risk of CNS depression.

How to manage the interaction:
Taking Kelebek 300mg/1500mcg Tablet with Codeine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Combining Remifentanil with Kelebek 300mg/1500mcg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Kelebek 300mg/1500mcg Tablet with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinMethadone
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Co-administration of Methadone and Kelebek 300mg/1500mcg Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Kelebek 300mg/1500mcg Tablet and Methadone, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinSodium oxybate
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Taking Kelebek 300mg/1500mcg Tablet with Sodium oxybate can increase the side effects on the central nervous system.

How to manage the interaction:
Although taking Kelebek 300mg/1500mcg Tablet and Sodium oxybate together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
GabapentinHydrocodone
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
When Hydrocodone is taken with Kelebek 300mg/1500mcg Tablet, the amount of Hydrocodone in the blood may be reduced.

How to manage the interaction:
Although there is a possible interaction between Kelebek 300mg/1500mcg Tablet and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinFentanyl
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Taking fentanyl with other drugs that cause central nervous system depression, such as Kelebek 300mg/1500mcg Tablet, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Kelebek 300mg/1500mcg Tablet may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
GabapentinPethidine
Severe
How does the drug interact with Kelebek 300mg/1500mcg Tablet:
Combining Meperidine with Kelebek 300mg/1500mcg Tablet can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Kelebek 300mg/1500mcg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well; get plenty of sleep.
  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Physical relaxation and massages can help provide symptomatic relief.
  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kelebek 300mg/1500mcg Tablet works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.

Kelebek 300mg/1500mcg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.

People taking Kelebek 300mg/1500mcg Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

If Kelebek 300mg/1500mcg Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Kelebek 300mg/1500mcg Tablet from the stomach. To avoid this, maintain a gap of two hours between Kelebek 300mg/1500mcg Tablet and antacid medicines.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Drug-Drug Interactions Checker List

  • HYDROCODONE
  • ACETAMINOPHEN
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • CYCLOBENZAPRINE
  • ALPRAZOLAM
  • PREGABALIN
  • QUETIAPINE
  • CHLORAMPHENICOL
  • METFORMIN

Special Advise

  • Close monitoring for suicidal thoughts/behaviour is required in people using Kelebek 300mg/1500mcg Tablet. 
  • Using Kelebek 300mg/1500mcg Tablet in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes, and hyperactivity. 
  • Let your doctor and the laboratory staff know if you are using Kelebek 300mg/1500mcg Tablet since Gabapentin may interfere with laboratory tests. 

Disease/Condition Glossary

Epilepsy is the central nervous system's disorder in which brain activity becomes abnormal, leading to rapid fits/seizures episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy fits.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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