KEPPRA 500MG INJECTION 5ML

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹128.5

(Inclusive of all Taxes)

₹19.3 Cashback (15%)

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Prescription drug

Whats That

About KEPPRA 500MG INJECTION 5ML

KEPPRA 500MG INJECTION 5ML is an anti-convulsant medicine used in the treatment of epilepsy. Epilepsy is a serious condition in which patients get more than two unprovoked seizures (fits/convulsions). KEPPRA 500MG INJECTION 5ML is used in the treatment of Partial Onset Seizures (a condition affecting a single area of the brain, mainly the temporal lobes), Myoclonic Seizures (sudden increase in the muscle tone due to shock-like jerks) in patients with Juvenile Myoclonic Epilepsy, Primary Generalized Tonic-Clonic Seizures.

KEPPRA 500MG INJECTION 5ML contains Levetiracetam as an active ingredient. It works by slowing down the abnormal signals that the brain gives, leading to episodes of seizures. It helps by suppressing specific brain sites responsible for abnormal activity and prevents the spread of electrical signals that cause seizures.

KEPPRA 500MG INJECTION 5ML is a parenteral medicine and will be administered intravenously as a 15-minute infusion by a healthcare professional. Hence, do not self-administer. This medicine may cause certain side effects such as drowsiness, disturbed sleep, light-headedness, dizziness, sleepiness, general weakness, and injection site reactions. Most of these side effects of KEPPRA 500MG INJECTION 5ML do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

KEPPRA 500MG INJECTION 5ML is not recommended for use if allergic to it. Hence inform your doctor if you have any conditions like severe liver/kidney disease, lung disease and Myasthenia gravis (muscle weakness). Pregnant and breastfeeding mothers should inform the doctor before receiving KEPPRA 500MG INJECTION 5ML. Avoid driving vehicles or operating machines which require concentration as KEPPRA 500MG INJECTION 5ML may cause dizziness. Abrupt stopping can result in withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings. KEPPRA 500MG INJECTION 5ML is not recommended for use in children below 16 years of age.

Uses of KEPPRA 500MG INJECTION 5ML

Epilepsy/Seizures

Directions for Use

KEPPRA 500MG INJECTION 5ML will be administered intravenously as a 15-minute infusion by a trained healthcare professional. Hence, do not self-administer.

Medicinal Benefits

KEPPRA 500MG INJECTION 5ML contains Levetiracetam as an active ingredient. It works by slowing down the abnormal signals that the brain gives, leading to episodes of seizures. It helps by suppressing specific brain sites responsible for abnormal activity and prevents the spread of electrical signals that cause seizures. It reduces the episodes of seizures but does not cure epilepsy.

Storage

Keep KEPPRA 500MG INJECTION 5ML out of the sight and reach of children.

Side effects of Keppra 500mg Injection 5ml

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Infection

Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
Wear masks, gloves and other protective clothing.
Cover sneezes and coughs with a medical mask or tissue or your elbow.
Take vaccinations to enhance your immunity to specific diseases.
Clean your utensils, linen and surfaces regularly.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

KEPPRA 500MG INJECTION 5ML is not recommended for use if allergic to it. This medicine should not be used if you have kidney disease, lung disease, muscle weakness (myasthenia gravis), difficulty in sleeping (sleep apnoea), severe liver disease, or a problem with alcohol or other prescription drugs. Hence, inform your doctor if you have any such conditions. Suicidal thoughts or actions can be caused in some patients receiving KEPPRA 500MG INJECTION 5ML, so pay attention to any sudden change in mood swings, behaviour, or feeling. Pregnant and breastfeeding mothers should inform the doctor before receiving KEPPRA 500MG INJECTION 5ML. Avoid driving vehicles or operating machines which require concentration as KEPPRA 500MG INJECTION 5ML may cause dizziness. Abrupt stopping can cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings. KEPPRA 500MG INJECTION 5ML is not recommended for use in children below 16 years of age.

Drug-Drug Interactions

LevetiracetamKetamine

Severe

LevetiracetamSodium oxybate

Severe

Drug-Drug Interactions

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LevetiracetamKetamine

Severe

How does the drug interact with Keppra 500mg Injection 5ml:
Using ketamine together with Keppra 500mg Injection 5ml may increase side effects (dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression).

How to manage the interaction:
Although there is a possible interaction between Ketamine and Keppra 500mg Injection 5ml, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

LevetiracetamSodium oxybate

Severe

How does the drug interact with Keppra 500mg Injection 5ml:
Using sodium oxybate together with Keppra 500mg Injection 5ml may increase side effects (drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination).

How to manage the interaction:
Taking Keppra 500mg Injection 5ml with Sodium oxybate together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

LevetiracetamDeferiprone

Severe

How does the drug interact with Keppra 500mg Injection 5ml:
Coadministration of deferiprone with Keppra 500mg Injection 5ml can increase the toxicity of the other.

How to manage the interaction:
Taking Keppra 500mg Injection 5ml with Deferiprone together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

LevetiracetamBuprenorphine

Severe

How does the drug interact with Keppra 500mg Injection 5ml:
Using buprenorphine together with Keppra 500mg Injection 5ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Concomitant administration of Keppra 500mg Injection 5ml alongside buprenorphine can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

It is advised to do regular exercise, which helps lower your anxiety and improve your sleep and self-image.
Try increasing your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
Include whole grains, vegetables, and fruits in your daily diet as a healthier option.
Reduce alcohol, caffeine, added sugar, high salt, and high fat intake.
Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Side Effects of KEPPRA 500MG INJECTION 5ML

Drowsiness
Disturbed sleep
Light-headedness
Dizziness
Sleepiness
General weakness
Injection site reactions

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:48 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does KEPPRA 500MG INJECTION 5ML work?

KEPPRA 500MG INJECTION 5ML contains Levetiracetam as an active ingredient. It works by slowing down the abnormal signals that the brain gives, leading to episodes of seizures.

Is it safe to drive while taking KEPPRA 500MG INJECTION 5ML?

If the intake of KEPPRA 500MG INJECTION 5ML makes you feel sleepy or dizzy, do not drive a motor vehicle or operate machinery after receiving it. Let your doctor know if you feel such symptoms after taking this medicine.

What would happen if I suddenly stopped receiving KEPPRA 500MG INJECTION 5ML?

Do not stop receiving KEPPRA 500MG INJECTION 5ML until instructed by your doctor. Abrupt discontinuation may cause confusion, depression, nervousness, sweating, and diarrhea. Your doctor may reduce the dose of this medicine gradually based on your condition.

Drug-Drug Interactions Checker List

RIFAMPICIN
LEVODOPA
THEOPHYLLINE
PROBENECID
PHENYTOIN
CIMETIDINE
CARBAMAZEPINE

Special Advise

Disease/Condition Glossary

Epilepsy: Epilepsy is a brain-related chronic disorder characterized by episodes of seizures (fits). In this condition, there is a chemical change in the brain cells (neurons) that leads to a sudden rise of electrical activity (impulse) in the brain, followed by sudden jerky movements of limbs or any body part. This disease cannot be cured but managed. KEPPRA 500MG INJECTION 5ML is used in treating Partial Onset Seizures (a condition affecting a single area of the brain, mainly the temporal lobes), Myoclonic Seizures (sudden increase in the muscle tone due to shock like jerks) in patients with Juvenile Myoclonic Epilepsy, Primary Generalized Tonic-Clonic Seizures.