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Klotrim 5Ml Inj

Klotrim 5Ml Inj

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Prescription drug
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Klotrim 5Ml Inj

Klotrim 5Ml Inj belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Klotrim 5Ml Inj does not work against infections caused by the virus, including cold and flu. 

Klotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Klotrim 5Ml Inj stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Klotrim 5Ml Inj will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Klotrim 5Ml Inj, please inform your doctor if you have any allergy (against any antibiotic), severe kidney or liver problems, porphyria (blood disorder), or blood problems which may cause bleeding or bruising. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Klotrim 5Ml Inj is not recommended for infants below 6 weeks. Keep your doctor informed about your medical history and your ongoing medications to rule out any side effects/interactions.

Uses of Klotrim 5Ml Inj

Bacterial infections

Medicinal Benefits

Klotrim 5Ml Inj belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Klotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Klotrim 5Ml Inj kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Klotrim 5Ml Inj is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria.

Directions for Use

Klotrim 5Ml Inj is administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Klotrim 5Ml Inj

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

 

Drug Warnings

Do not take Klotrim 5Ml Inj if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (a rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Klotrim 5Ml Inj if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. 

Drug Interactions

Drug-Drug Interactions: Klotrim 5Ml Inj may have interaction with a blood thinner (warfarin), anticonvulsants (phenytoin), digitalis glycoside (digoxin), oral hypoglycemic agents, anti-HIV (zidovudine), anti-arrhythmic (procainamide).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), hematologic (blood) toxicity, hypersensitivity reactions, porphyria (rare blood problem that affects the skin or nervous system), folate deficiency, crystalluria (cloudy urine), dialysis, urinary obstruction, kidney and liver dysfunction.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENYTOIN
  • DIGOXIN
  • ZIDOVUDINE
  • PROCAINAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Special Advise

  • Klotrim 5Ml Inj may affect certain laboratory test results such as blood tests. Inform the lab technician that you are taking Klotrim 5Ml Inj. 
  • Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed Klotrim 5Ml Inj for a longer duration, to know if the medicine is working properly.

 

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body cells. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

Country of origin

India

Manufacturer/Marketer address

37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Other Info - KLO0116

FAQs

Klotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Klotrim 5Ml Inj kills the bacteria and stops their growth. Thus, it helps to treat bacterial infections.
Klotrim 5Ml Inj causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
Diarrhoea might be a side-effect of Klotrim 5Ml Inj. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, inform your doctor. Do not take anti-diarrheal medicine on your own.
Klotrim 5Ml Inj may affect certain laboratory test results. Inform the lab technician that you are taking Klotrim 5Ml Inj.
Klotrim 5Ml Inj may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Klotrim 5Ml Inj.

Disclaimer

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Alcohol

Caution

Avoid alcohol consumption while taking Klotrim 5Ml Inj to prevent unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor before taking Klotrim 5Ml Inj if you are pregnant. Klotrim 5Ml Inj may cause fetal harm. Your doctor will prescribe Klotrim 5Ml Inj only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Klotrim 5Ml Inj as it may cause bilirubin displacement and kernicterus (brain damage resulting from high levels of bilirubin in the blood). Please consult your doctor if you have any concerns.

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Driving

Caution

It is unknown whether Klotrim 5Ml Inj affects your ability to drive and operate machinery. Drive only if you are physically stable and mentally focused.

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Liver

Caution

Please inform your doctor before taking Klotrim 5Ml Inj if you have liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

Please inform your doctor before taking Klotrim 5Ml Inj if you have kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Klotrim 5Ml Inj is not recommended for infants below 6 weeks.

Author Details

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