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Reviewed By Sunny S , MBBS
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About Kofkil Syrup

Kofkil Syrup belongs to a class of respiratory medications called 'expectorant' primarily used to treat cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from the airways. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce thick mucus, while a chesty cough (wet cough) produces mucous or sputum that helps clear the airways.

Kofkil Syrup consists of four medicines, namely: Bromohexine (mucolytic), Terbutaline (bronchodilator), Ammonium chloride (irritant/expectorant) and Menthol (cooling agent). Bromhexine makes sputum less viscous and makes it easier to cough out. Terbutaline works by dilating (expanding) and relaxing the air passages in the lungs, making breathing easier, especially in people with airway problems or respiratory obstructive disorders. Ammonium chloride is an expectorant that decreases the stickiness of mucous and helps remove it from the airways. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Kofkil Syrup is available in oral syrup and suspension. The most common side effects of Kofkil Syrup are nausea, diarrhoea, bloating, indigestion, vomiting, stomach upset, sweating, dizziness, headache and skin rash. Most of these side effects of Kofkil Syrup do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you have any allergic reactions to Kofkil Syrup or any other medication. Brief your medical history to the doctor if you have any heart, liver, kidney, lung diseases, depression and Parkinson's disease before taking Kofkil Syrup. Kofkil Syrup can cause sleepiness; hence avoid taking alcohol while using Kofkil Syrup. Kofkil Syrup may affect your ability to drive. It is advised not to drive whilst taking this medicine. Check with your doctor if you are pregnant, currently breastfeeding or taking any other prescribed or non-prescribed drugs. 

Uses of Kofkil Syrup

Cough

Directions for Use

Your doctor will advise on how often you take Kofkil Syrup based on your medical condition. Shake the bottle well before use. Check the label for directions and take Kofkil Syrup with or without food with a measuring cup in the dose and duration prescribed by the doctor.

Medicinal Benefits

Kofkil Syrup is a respiratory medication primarily used to treat cough. Kofkil Syrup consists of four medicines: Bromhexine (mucolytic), Terbutaline (bronchodilator), Ammonium chloride (irritant/expectorant) and Menthol (cooling agent). Bromhexine is a 'mucolytic agent' that makes sputum less viscous and easier to cough. Terbutaline belongs to the bronchodilators class that dilates (expands) and relaxes the air passages in the lungs, making breathing easier, especially in people with airway problems or respiratory obstructive disorders.  Ammonium chloride is an expectorant that decreases the stickiness of mucous and helps remove it from the airways. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kofkil Syrup

  • Nausea
  • Diarrhea
  • Bloating
  • Indigestion
  • Vomiting
  • Stomach upset
  • Sweating
  • Dizziness
  • Headache
  • Skin rash

Drug Warnings

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kofkil Syrup. If you are suffering from fits (epilepsy/seizures) or have a history of fits, please inform your doctor before taking Kofkil Syrup as it may increase the risk of recurrent fits. Kofkil Syrup is not recommended for children below 6 years of age and body weight less than 25 kg, as the safety and effectiveness were not established. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Kofkil Syrup. If you experience constipation, leg cramps, numbness or tingling, increased urination or thirst, muscle weakness or irregular heartbeats, contact your doctor, as it may be due to low potassium levels in the blood. Drink plenty of fluids while taking Kofkil Syrup to loosen mucus. If you have diabetes, fits, high blood pressure, overactive thyroid or heart problems, please inform your doctor before taking Kofkil Syrup.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Kofkil Syrup.
  • Know your triggers like allergens, such as pollen, dust and food items that make your asthma and other respiratory diseases severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Drink extra fluids while you take Kofkil Syrup to help loosen congestion and lubricate the throat.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

FAQs

Kofkil Syrup consists of four medicines: Bromhexine, Terbutaline, Ammonium chloride, and Menthol. Kofkil Syrup relieves cough symptoms by thinning the cough/mucus, making it less viscous, suppressing coughing and decreasing throat irritation by providing a soothing effect. This helps in easy coughing out of phlegm and makes breathing easier.

Yes, you may experience headaches and shakiness after using Kofkil Syrup. Drink plenty of water and take rest to manage your headache. Shakiness goes away gradually. Consult your doctor if these symptoms persist longer.

Kofkil Syrup is not recommended for use if you have a stomach ulcer since mucolytics like Bromohexine may disrupt the gastric mucosal barrier; therefore cautiously administered in patients with a stomach ulcer.

No, you are not recommended to take propranolol or other beta-blockers used to lower raised blood pressure with Kofkil Syrup as it may reduce the effectiveness of both medicines. Also, propranolol may cause a narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, you should consult a doctor before using other medicines with Kofkil Syrup.

Kofkil Syrup should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Kofkil Syrup as it may increase blood sugar levels.

Kofkil Syrup contains terbutaline, which may decrease the potassium levels in your body, leading to hypokalemia. If you have a low potassium level, let your doctor know this before taking the Kofkil Syrup.

Drug-Drug Interactions Checker List

  • DEXTROAMPHETAMINE
  • AMPHETAMINE
  • DULOXETINE
  • ESCITALOPRAM
  • QUETIAPINE
  • SERTRALINE
  • ISOCARBOXAZID
  • SELEGILINE
  • PHENELZINE
  • RASAGILINE
  • TRANYLCYPROMINE
  • ETHANOL
  • DIPHENHYDRAMINE
  • CODEINE
  • PREGABALIN
  • QUINIDINE
  • ALPRAZOLAM
  • METHYLENE BLUE

Special Advise

  • Regularly monitoring blood sugar levels and serum potassium levels is required while taking Kofkil Syrup.
  • ECG (electrocardiogram) of the heart is recommended, and the heartbeat should be closely monitored. 
  • Kofkil Syrup should not be given to children less than 6 years of age and weighing less than 25 kg.

Disease/Condition Glossary

Cough: It occurs as a reflex action in the throat when there is mucus or any other foreign irritant in it. Cough can be dry or productive. A productive cough (wet cough) develops sputum (phlegm or mucus) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing out thick, solid white mucus, it indicates that you may have a bacterial infection in the airways. Clear or light-coloured mucus indicates allergies or minor infections in the respiratory tract, and yellow or green mucus indicates a respiratory infection. 

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