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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
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About Kofpause D Syrup

Kofpause D Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum.

Kofpause D Syrup contains Chlorpheniramine maleate, Phenylephrine and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Kofpause D Syrup helps provide relief from dry cough.

Your doctor will recommend the dose and duration of Kofpause D Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. Most of these side effects of Kofpause D Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or breastfeeding. Kofpause D Syrup is not recommended for children below 12 years of age. If you are about to undergo medical tests or surgery, please inform your doctor that you are taking Kofpause D Syrup. Kofpause D Syrup may cause dizziness, so drive or operate machinery only if you are alert. Avoid alcohol consumption as it may cause increased dizziness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Kofpause D Syrup

Dry cough

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Kofpause D Syrup is a combination medicine belonging to a class of drugs called 'cough and cold preparations' primarily used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine is a decongestant that helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Kofpause D Syrup helps relieve cough, cold and allergic symptoms.

Storage

Keep Kofpause D Syrup out of reach and sight of children.
Side effects of Kofpause D Syrup
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

If you are allergic to Kofpause D Syrup or any other medicines, please tell your doctor. Consult your doctor if you are pregnant or breastfeeding. Kofpause D Syrup is not recommended for children below 12 years of age. Avoid taking Kofpause D Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor if you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Kofpause D Syrup:
Co-administration of Kofpause D Syrup and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Kofpause D Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kofpause D Syrup:
Taking Tranylcypromine with Kofpause D Syrup can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Kofpause D Syrup with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Kofpause D Syrup:
Co-administration of Phenelzine and Kofpause D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Kofpause D Syrup can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Kofpause D Syrup:
Co-administration of Isocarboxazid with Kofpause D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Kofpause D Syrup and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Kofpause D Syrup:
Co-administration of Pargyline and Kofpause D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Kofpause D Syrup and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kofpause D Syrup:
Co-administration of Kofpause D Syrup and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Kofpause D Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kofpause D Syrup:
Taking Rasagiline with Kofpause D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Kofpause D Syrup with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kofpause D Syrup:
Taking Kofpause D Syrup with Propofol may lead to increased levels of Kofpause D Syrup leading to side effects like high blood pressure.

How to manage the interaction:
Taking Kofpause D Syrup with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Kofpause D Syrup:
Taking Furazolidone with Kofpause D Syrup can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Kofpause D Syrup is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Kofpause D Syrup only after 14 days of stopping Furazolidone.
How does the drug interact with Kofpause D Syrup:
Co-administration of Kofpause D Syrup with Sevoflurane can increase the levels of Kofpause D Syrup and lead to side effects.

How to manage the interaction:
Taking Kofpause D Syrup with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Side Effects of Kofpause D Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kofpause D Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Consult your doctor before taking Kofpause D Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Kofpause D Syrup 72 hours prior to the surgery.

It is not recommended to take Kofpause D Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Kofpause D Syrup should be taken at least 14 days after the last dose of anti-depressants.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the scheduled dose. Do not take extra medicine to make up for the missed dose.

Kofpause D Syrup may rarely worsen the symptoms of glaucoma. Therefore, Kofpause D Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ASPIRIN
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE

Special Advise

  • Talk to your doctor if your symptoms do not improve even after taking Kofpause D Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash or headache after taking Kofpause D Syrup. 
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Kofpause D Syrup.

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Cough may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs. A dry cough does not produce sputum. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an infection in the respiratory tract. 

Have a query?

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Alcohol

Caution

Avoid consumption of alcohol with Kofpause D Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Kofpause D Syrup.

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Pregnancy

Caution

The safety of Kofpause D Syrup in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Kofpause D Syrup is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if Kofpause D Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Kofpause D Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Kofpause D Syrup.

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Liver

Caution

Take Kofpause D Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Kofpause D Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Kofpause D Syrup is not recommended for children below 12 years of age. However, please consult a doctor if you have any concerns.

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