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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Kolibitor Injection 5 ml

Kolibitor Injection 5 ml belongs to the class of medicines called antibiotics. It is used to treat or prevent lung infections caused by bacteria called Pneumocystis jirovecii and Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), ear infections such as otitis media, respiratory tract infections such as bronchitis, and nocardiosis, which can affect the skin, lungs and brain. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Kolibitor Injection 5 ml does not work against infections, flu or cold symptoms caused by the virus.

Kolibitor Injection 5 ml contains two antibiotics, Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection.

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina) as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome.

Uses of Kolibitor Injection 5 ml

Bacterial infections

Directions for Use

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Kolibitor Injection 5 ml is a combination of two antibiotics, Sulfamethoxazole and Trimethoprim. It is used to treat or prevent lung infections caused by a bacteria called Pneumocystis jirovecii and infections caused by a bacteria called Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media, and nocardiosis which can affect the skin, lungs and brain. Additionally, Kolibitor Injection 5 ml is used to treat brucellosis (a bacterial infection that spreads from animals to people) if other treatments are not effective and in combination with other agents in line with national treatment guidelines. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria and stopping the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kolibitor Injection 5 ml

  • Abnormal heartbeats
  • Headache
  • Diarrhoea
  • Skin rashes
  • Nausea
  • Thrush or candidiasis (a fungal infection that affects the mouth or vagina)

Drug Warnings

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome. If you are elderly, malnourished or underweight, inform your doctor before receiving Kolibitor Injection 5 ml.

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
sulfamethoxazoleClozapine
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Kolibitor Injection 5 ml:
Taking Kolibitor Injection 5 ml with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Kolibitor Injection 5 ml and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
sulfamethoxazoleClozapine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
The combined use of Kolibitor Injection 5 ml and clozapine may increase the risk or severity of toxicity.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Kolibitor Injection 5 ml, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
TrimethoprimCalcium folinate
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Co-administration of Calcium folinate with Kolibitor Injection 5 ml may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between calcium folinate and Kolibitor Injection 5 ml, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TrimethoprimTetracaine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Co-administration of Kolibitor Injection 5 ml with tetracaine can result in blood disorders.

How to manage the interaction:
Although there is an interaction between Kolibitor Injection 5 ml and tetracaine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
TrimethoprimCandesartan
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking Kolibitor Injection 5 ml with candesartan can increase the risk of hyperkalemia (high potassium levels in the blood) and kidney problems.

How to manage the interaction:
Although there is an interaction between candesartan and Kolibitor Injection 5 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimOlmesartan medoxomil
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking olmesartan medoxomil with Kolibitor Injection 5 ml may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil with Kolibitor Injection 5 ml may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
TrimethoprimRopivacaine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking Ropivacaine with Kolibitor Injection 5 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is an interaction between ropivacaine and Kolibitor Injection 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath. Do not stop using any medications without a doctor's advice.
TrimethoprimValsartan
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Using Kolibitor Injection 5 ml together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Kolibitor Injection 5 ml together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Co-administration of Kolibitor Injection 5 ml with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Kolibitor Injection 5 ml with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimLosartan
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Coadministration of Losartan with Kolibitor Injection 5 ml can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan with Kolibitor Injection 5 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Kolibitor Injection 5 ml to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while taking Kolibitor Injection 5 ml.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMANTADINE
  • CICLOSPORIN
  • AZATHIOPRINE
  • METHOTREXATE
  • PYRIMETHAMINE
  • SPIRONOLACTONE
  • WARFARIN
  • PHENYTOIN
  • GLIBENCLAMIDE
  • TOLBUTAMIDE
  • GLIPIZIDE
  • REPAGLINIDE
  • DIGOXIN
  • PROCAINAMIDE
  • LAMIVUDINE
  • ZIDOVUDINE
  • PREDNISOLONE
  • RIFAMPICIN
  • FOLINIC ACID

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and causes infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.

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