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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Kolibitor Injection 5 ml

Kolibitor Injection 5 ml belongs to the class of medicines called antibiotics. It is used to treat or prevent lung infections caused by bacteria called Pneumocystis jirovecii and Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), ear infections such as otitis media, respiratory tract infections such as bronchitis, and nocardiosis, which can affect the skin, lungs and brain. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Kolibitor Injection 5 ml does not work against infections, flu or cold symptoms caused by the virus.

Kolibitor Injection 5 ml contains two antibiotics, Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection.

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina) as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Kolibitor Injection 5 ml

Bacterial infections

Medicinal Benefits

Kolibitor Injection 5 ml is a combination of two antibiotics, Sulfamethoxazole and Trimethoprim. It is used to treat or prevent lung infections caused by a bacteria called Pneumocystis jirovecii and infections caused by a bacteria called Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media, and nocardiosis which can affect the skin, lungs and brain. Additionally, Kolibitor Injection 5 ml is used to treat brucellosis (a bacterial infection that spreads from animals to people) if other treatments are not effective and in combination with other agents in line with national treatment guidelines. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria and stopping the spread of infection.

Side Effects of Kolibitor Injection 5 ml

  • Abnormal heartbeats
  • Headache
  • Diarrhoea
  • Skin rashes
  • Nausea
  • Thrush or candidiasis (a fungal infection that affects the mouth or vagina)

Directions for Use

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome. If you are elderly, malnourished or underweight, inform your doctor before receiving Kolibitor Injection 5 ml.

Therapeutic Class

ANTIBIOTIC COMBINATION

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
sulfamethoxazoleClozapine
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Kolibitor Injection 5 ml:
Taking Kolibitor Injection 5 ml with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Kolibitor Injection 5 ml and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
sulfamethoxazoleClozapine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
The combined use of Kolibitor Injection 5 ml and clozapine may increase the risk or severity of toxicity.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Kolibitor Injection 5 ml, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
TrimethoprimCaptopril
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking captopril with Kolibitor Injection 5 ml may increase the risk of hyperkalemia (high level of potassium in the blood) and kidney problems.

How to manage the interaction:
Although there is a interaction between Kolibitor Injection 5 ml and captopril, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Co-administration of Kolibitor Injection 5 ml with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Kolibitor Injection 5 ml with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimPotassium gluconate
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking potassium gluconate with Kolibitor Injection 5 ml can increase the risk of high potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Kolibitor Injection 5 ml and Potassium gluconate, you can take these medicines together if prescribed by your doctor. However, if you are feeling sick, feeling weak, confused, or having a weak or irregular heartbeat contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TrimethoprimRopivacaine
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Using ropivacaine with Kolibitor Injection 5 ml can cause higher levels of Kolibitor Injection 5 ml in the blood.

How to manage the interaction:
Although taking Ropivacaine and Kolibitor Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion contact your doctor immediately. Do not stop using any medications without a doctor's advice.
TrimethoprimPotassium acetate
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking potassium acetate with Kolibitor Injection 5 ml may increase potassium levels in the blood which can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Kolibitor Injection 5 ml and Potassium acetate, you can take these medicines together if prescribed by your doctor. However, if you have unusual symptoms contact your doctor right away. Do not discontinue any medications without consulting your doctor.
TrimethoprimFosphenytoin
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking fosphenytoin with Kolibitor Injection 5 ml may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between fosphenytoin and Kolibitor Injection 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience, weakness, vomiting, blurry vision, or trouble speaking. Do not discontinue any medications without consulting a doctor.
TrimethoprimCandesartan
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Taking Kolibitor Injection 5 ml with candesartan can increase the risk of hyperkalemia (high potassium levels in the blood) and kidney problems.

How to manage the interaction:
Although there is an interaction between candesartan and Kolibitor Injection 5 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimMethotrexate
Severe
How does the drug interact with Kolibitor Injection 5 ml:
Coadministration of Kolibitor Injection 5 ml with methotrexate can increase the risk or severity of blood disorders.

How to manage the interaction:
Although there is a possible interaction between Kolibitor Injection 5 ml and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMANTADINE
  • CICLOSPORIN
  • AZATHIOPRINE
  • METHOTREXATE
  • PYRIMETHAMINE
  • SPIRONOLACTONE
  • WARFARIN
  • PHENYTOIN
  • GLIBENCLAMIDE
  • TOLBUTAMIDE
  • GLIPIZIDE
  • REPAGLINIDE
  • DIGOXIN
  • PROCAINAMIDE
  • LAMIVUDINE
  • ZIDOVUDINE
  • PREDNISOLONE
  • RIFAMPICIN
  • FOLINIC ACID

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Kolibitor Injection 5 ml to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while taking Kolibitor Injection 5 ml.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and causes infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.

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