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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Kronostar 500mg Tablet 10's

Kronostar 500mg Tablet 10's belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Kronostar 500mg Tablet 10's is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations.
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Kronostar 500mg Tablet 10's is a combination of two drugs, namely: Sodium valproate and Valproic acid. Kronostar 500mg Tablet 10's works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Kronostar 500mg Tablet 10's increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Kronostar 500mg Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side-effects persistently.
 
Do not take Kronostar 500mg Tablet 10's if you are pregnant, as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Kronostar 500mg Tablet 10's. Consult your doctor before taking Kronostar 500mg Tablet 10's if you are breastfeeding. Kronostar 500mg Tablet 10's causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Kronostar 500mg Tablet 10's as it could lead to an increased risk of seizures. Care should be taken while giving Kronostar 500mg Tablet 10's to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Kronostar 500mg Tablet 10's

Epilepsy, Mood disorder, Migraine

Medicinal Benefits

Kronostar 500mg Tablet 10's is a combination of two drugs, namely: Sodium valproate and Valproic acid. Kronostar 500mg Tablet 10's is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Kronostar 500mg Tablet 10's decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Kronostar 500mg Tablet 10's is used to treat certain forms of epilepsy such as petit mal epilepsy (short-term unconsciousness due to disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Kronostar 500mg Tablet 10's may also be used to treat epilepsy which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy which is not associated with movements and epilepsy with symptoms affecting perception and deliberate movements. Kronostar 500mg Tablet 10's is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

Side Effects of Kronostar 500mg Tablet 10's

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

Directions for Use

Take Kronostar 500mg Tablet 10's with or 1hour prior food. Swallow Kronostar 500mg Tablet 10's a whole with a glass of water, do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Kronostar 500mg Tablet 10's if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Kronostar 500mg Tablet 10's. Consult your doctor immediately if you experience suicidal tendencies while taking Kronostar 500mg Tablet 10's. Please do not stop taking Kronostar 500mg Tablet 10's without consulting your doctor to avoid the worsening of seizures. Do not take Kronostar 500mg Tablet 10's if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Kronostar 500mg Tablet 10's. Consult your doctor before taking Kronostar 500mg Tablet 10's if you are breastfeeding. Kronostar 500mg Tablet 10's causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Kronostar 500mg Tablet 10's as it could lead to increased risk of seizures. Care should be taken while giving Kronostar 500mg Tablet 10's to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Kronostar 500 Tablet 10's:
Combining Sodium phenylbutyrate and Kronostar 500 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Kronostar 500 Tablet 10's is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Kronostar 500 Tablet 10's:
Coadministration of Glycerol phenylbutyrate and Kronostar 500 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Kronostar 500 Tablet 10's together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Kronostar 500 Tablet 10's with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Kronostar 500 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Using buprenorphine together with Kronostar 500 Tablet 10's may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Kronostar 500 Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Leflunomide and Kronostar 500 Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Kronostar 500 Tablet 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Teriflunomide and Kronostar 500 Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Kronostar 500 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Vorinostat with Kronostar 500 Tablet 10's can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Kronostar 500 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Lithium with Kronostar 500 Tablet 10's can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Kronostar 500 Tablet 10's can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
Co-administration of Ketamine and Kronostar 500 Tablet 10's can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Kronostar 500 Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Kronostar 500 Tablet 10's:
The combined use of Ertapenem and Kronostar 500 Tablet 10's can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Kronostar 500 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ZIDOVUDINE
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • LEVONORGESTREL
  • MEFLOQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan; this helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Special Advise

  • Regular monitoring of blood count is advised while taking Kronostar 500mg Tablet 10's as it may cause spontaneous bleeding or bruising.
  • Inform your doctor that you are taking Kronostar 500mg Tablet 10's if you are due to have any surgery or dental intervention.
  • Consult your doctor if you experience irregular periods while taking Kronostar 500mg Tablet 10's.
  • If you are of child-bearing age, use effective contraception while taking Kronostar 500mg Tablet 10's.

Author Details

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Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows. 

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light. 

Kronostar 500mg Tablet 10's Substitute

Substitutes safety advice
  • Encorate Chrono 500 Tablet 10's

    9.32per tablet
  • Valparin Chrono 500 Tablet 15's

    9.33per tablet
  • Valprol CR 500 Tablet 15's

    by AYUR

    9.33per tablet
  • Epilex Chrono 500 CR Tablet 15's

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    9.33per tablet
  • Torvate Chrono 500 Tablet 10's

    7.16per tablet
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