Kryxana 200 mg Tablet 21's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Sureshvarma D , MPharma

MRP ₹25980

(Inclusive of all Taxes)

₹3117.6 Cashback (12%)

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Whats That

About Kryxana 200 mg Tablet

Kryxana 200 mg Tablet belongs to the group of anti-cancer medicines called cyclin-dependent kinase (CDK) inhibitors used to treat a type of breast cancer that is locally advanced or metastatic (has spread to other parts of the body). Breast cancer is a type of cancer that develops in the breast when the breast cells begin to grow abnormally.

Kryxana 200 mg Tablet contains ‘Ribociclib’, which works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

You are advised to take Kryxana 200 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as diarrhoea, nausea, vomiting, constipation, hair loss, fatigue, dizziness, back pain, and headache. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.

Avoid taking Kryxana 200 mg Tablet if you are pregnant or breastfeeding. Kryxana 200 mg Tablet may cause tiredness and dizziness, so drive only if you are alert. Kryxana 200 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Kryxana 200 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Kryxana 200 mg Tablet

Breast cancer

Directions for Use

Swallow Kryxana 200 mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Kryxana 200 mg Tablet belongs to the group of anti-cancer medicines called cyclin-dependent kinase (CDK) inhibitors used to treat a type of breast cancer that is locally advanced or metastatic (has spread to other parts of the body). Kryxana 200 mg Tablet works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

Storage

Keep Kryxana 200 mg Tablet out of reach and sight of children.

Side effects of Kryxana 200 mg Tablet

Increased Risk Of Infection Due To Low Neutrophil Count

Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
Avoid contact with people who are sick.
Wash your hands regularly with soap and water.
Avoid unpasteurized dairy products.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Low White Blood Cell Count

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not take Kryxana 200 mg Tablet if you are allergic to any of its components. Talk to your doctor if you have a fever, sore throat, mouth ulcers due to infections, liver problems, heart/heart rhythm disorders, or low levels of electrolytes. Avoid taking Kryxana 200 mg Tablet if you are pregnant or breastfeeding. Kryxana 200 mg Tablet may cause dizziness, so drive only if you are alert. Kryxana 200 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol with Kryxana 200 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Kryxana 200 mg Tablet to rule out any side effects/interactions.

Drug-Drug Interactions

RibociclibBudesonide

Critical

RibociclibRanolazine

Critical

Drug-Drug Interactions

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RibociclibBudesonide

Critical

How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of Budesonide and Kryxana 200 mg Tablet may increase the absorption of the medication from budesonide into the blood stream.

How to manage the interaction:
Taking Kryxana 200 mg Tablet with Budesonide can cause an interaction, consult a doctor before taking it. Consult a doctor if experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without talking to a doctor.

RibociclibRanolazine

Critical

How does the drug interact with Kryxana 200 mg Tablet:
When Kryxana 200 mg Tablet is taken with Ranolazine, may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ranolazine with Rifampicin is not recommended, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as excessive drowsiness, dizziness, lightheadedness, fainting, confusion, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.

RibociclibBaricitinib

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of baricitinib and Kryxana 200 mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Kryxana 200 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

RibociclibFlecainide

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of Flecainide with Kryxana 200 mg Tablet can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Co-administration of Flecainide with Kryxana 200 mg Tablet can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience any palpitations, dizziness, or shortness of breath, contact a doctor. Do not stop using any medications without a doctor's advice.

RibociclibDoxepin

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Co-administration of Kryxana 200 mg Tablet with Doxepin can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Kryxana 200 mg Tablet with Doxepin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

RibociclibMifepristone

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Co-administration of Kryxana 200 mg Tablet with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Kryxana 200 mg Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

RibociclibAtomoxetine

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Taking Atomoxetine with Kryxana 200 mg Tablet can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Atomoxetine and Kryxana 200 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without talking to a doctor.

RibociclibFluconazole

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Taking Fluconazole with Kryxana 200 mg Tablet may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Fluconazole can be taken with Kryxana 200 mg Tablet if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.

RibociclibHydroxyzine

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Taking hydroxyzine with Kryxana 200 mg Tablet increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Hydroxyzine and Kryxana 200 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

RibociclibGoserelin

Severe

How does the drug interact with Kryxana 200 mg Tablet:
Taking Goserelin and Kryxana 200 mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Goserelin and Kryxana 200 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
Avoid fast food, fried food, processed meats, refined carbs and added sugar.
Get optimal sleep; rest well.

Side Effects of Kryxana 200 mg Tablet

Stomach upset
Diarrhoea
Nausea
Vomiting
Tiredness
Constipation
Hair loss
Weakness
Dizziness/light-headedness
Headache
Cough
Reduced appetite
Painful and frequent urination
Fever

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Kryxana 200 mg Tablet work?

Kryxana 200 mg Tablet works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

Does Kryxana 200 mg Tablet affect fertility?

Kryxana 200 mg Tablet might cause fertility problems and may affect your ability to father a child. Talk to your doctor if you have any concerns regarding this.

What foods should I avoid while taking Kryxana 200 mg Tablet ?

Avoid pomegranate/pomegranate juice and grapefruit/grapefruit juice while taking Kryxana 200 mg Tablet as these might increase the amount of Kryxana 200 mg Tablet in blood.

Does Kryxana 200 mg Tablet cause heart rhythm problems?

Kryxana 200 mg Tablet may cause a heart problem called QT prolongation, which causes abnormal heartbeat. Inform your doctor if you have/had any heart problems, heart failure, irregular heartbeat, or QT prolongation. Regular monitoring of heart activity before and during treatment with Kryxana 200 mg Tablet is advised.

Can I stop taking Kryxana 200 mg Tablet on my own?

Do not stop taking Kryxana 200 mg Tablet on your own. You are advised to take Kryxana 200 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kryxana 200 mg Tablet .

Does Kryxana 200 mg Tablet cause dry mouth?

Dry mouth could be a side-effect of Kryxana 200 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

PACLITAXEL
DOXORUBICIN
ZOLPIDEM
OXYCODONE
SOTALOL

Special Advise

To monitor liver functioning, amount of blood cells, and electrolytes, your doctor might advise regular blood tests before and during the treatment with Kryxana 200 mg Tablet .
Regular monitoring of heart activity before and during treatment with Kryxana 200 mg Tablet is advised.
Kryxana 200 mg Tablet might cause heart rhythm problems, liver problems and neutropenia (low white blood cell count); therefore, regular tests are recommended while taking Kryxana 200 mg Tablet .
If you are a woman of childbearing potential, use effective contraception while taking Kryxana 200 mg Tablet and for at least 21 days after the last dose.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in the breast when the breast cells begin to grow abnormally. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.