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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Laregab-NT LS 200/10 Tablet 1

Laregab-NT LS 200/10 Tablet 1 is a combination medicine indicated for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Laregab-NT LS 200/10 Tablet 1 contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, and tingling sensations. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Laregab-NT LS 200/10 Tablet 1 may cause drowsiness and dizziness, so drive only if you are alert. Laregab-NT LS 200/10 Tablet 1 should not be given to children unless prescribed by the doctor. Avoid consuming alcohol along with Laregab-NT LS 200/10 Tablet 1 as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Laregab-NT LS 200/10 Tablet 1

Neuropathic pain

Directions for Use

Take Laregab-NT LS 200/10 Tablet 1 with or without food. Swallow Laregab-NT LS 200/10 Tablet 1 as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Laregab-NT LS 200/10 Tablet 1 is used to treat neuropathic pain. Laregab-NT LS 200/10 Tablet 1 is a combination of two drugs: Gabapentin and Nortriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Nortriptyline belongs to tricyclic antidepressants. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Nortriptyline works by preventing the released chemical messenger in brains (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain and prevents the movement of pain signals in the brain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Laregab-NT LS 200/10 Tablet 1 if you are allergic to any of its contents. Inform your doctor before taking Laregab-NT LS 200/10 Tablet 1 if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Laregab-NT LS 200/10 Tablet 1 may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Laregab-NT LS 200/10 Tablet 1 as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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NortriptylineSafinamide
Critical
NortriptylineTranylcypromine
Critical

Drug-Drug Interactions

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NortriptylineSafinamide
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
NortriptylineTranylcypromine
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylineLinezolid
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineZiprasidone
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Using Laregab-NT LS 200/10 Tablet 10's together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Laregab-NT LS 200/10 Tablet 10's is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NortriptylineSelegiline
Critical
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Co-administration of Laregab-NT LS 200/10 Tablet 10's with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineHalofantrine
Severe
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Using halofantrine together with Laregab-NT LS 200/10 Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Laregab-NT LS 200/10 Tablet 10's with Halofantrine can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - irregular heart rhythm, heart problems, long qt syndrome, diarrhea, vomiting, dizziness, fainting, shortness of breath, or heart palpitations - call a doctor right away. Do not stop using any medications without a doctor's advice.
NortriptylinePhenylephrine
Severe
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Co-administration of Laregab-NT LS 200/10 Tablet 10's with phenylephrine may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Laregab-NT LS 200/10 Tablet 10's and phenylephrine together can result in an interaction, it can be taken if a doctor has prescribed it. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.
NortriptylineSotalol
Severe
How does the drug interact with Laregab-NT LS 200/10 Tablet 10's :
Coadministration of Laregab-NT LS 200/10 Tablet 10's with Sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Laregab-NT LS 200/10 Tablet 10's with Sotalol together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet, as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Laregab-NT LS 200/10 Tablet 1 Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Laregab-NT LS 200/10 Tablet 1 contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

To treat your condition effectually, continue taking Laregab-NT LS 200/10 Tablet 1 for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Laregab-NT LS 200/10 Tablet 1; your doctor will reduce the dose gradually.

Laregab-NT LS 200/10 Tablet 1 may cause dry mouth. In that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Laregab-NT LS 200/10 Tablet 1 helps in the treatment of diabetic neuropathy (nerve damage in diabetic patients). However, please consult your doctor before starting Laregab-NT LS 200/10 Tablet 1 if you have diabetes.

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Special Advise

  • If you are taking any antacids containing aluminum or magnesium, try to keep at least 2 hours gap between intake of Laregab-NT LS 200/10 Tablet 1 and these antacids to avoid drug-drug interaction.
  • Laregab-NT LS 200/10 Tablet 1 can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position

 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease caused due to damage of sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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