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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

CALCITRIOL-1MCG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Laretol Injection 1ml

Laretol Injection 1ml belongs to the class of a vitamin D analogue. Calcitriol is used to treat or prevent some complications associated with long-term kidney dialysis, such as low calcium levels (Hypocalcaemia). Hypocalcaemia is characterized by low levels of calcium in the blood. A lack or inadequacy of vitamin D can cause hypocalcaemia.

Laretol Injection 1ml contains calcitriol. It increases the levels of vitamin D in your blood, which in turn raises calcium levels thus, it helps to treat patients with low levels of calcium who are on chronic renal dialysis.

Laretol Injection 1ml is given by a health care professional in a hospital or clinic setting. In some cases, Laretol Injection 1ml can cause side effects like Nausea, headache, constipation, or pain/discomfort at the injection site may occur. Most of these side effects of Laretol Injection 1ml do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you have too much calcium or vitamin D in the blood before receiving the Laretol Injection 1ml. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Laretol Injection 1ml

Hypocalcaemia (low calcium levels)

Directions for Use

Laretol Injection 1ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Laretol Injection 1ml contains calcitriol. It increases the levels of vitamin D in your blood, which raises calcium levels; thus, it helps treat patients with low levels of calcium who are on chronic renal dialysis. Calcitriol is usually used along with a certain diet, supplements, and sometimes other medications. It can also help to build and keep strong bones.

Storage

Keep Laretol Injection 1ml out of reach and sight of children.

Drug Warnings

Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are with malabsorption syndrome (difficulty absorbing nutrition from food) or if you are diagnosed with too much calcium or vitamin D in the blood before receiving the Laretol Injection 1ml. Laretol Injection 1ml should not be used for pregnant and lactation mothers unless clearly necessary. So, inform your doctor if you are a pregnant woman or a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Laretol Injection 1ml.

Drug-Drug Interactions

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CalcitriolCalcifediol
Severe

Drug-Drug Interactions

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How does the drug interact with Laretol Injection 1ml:
Co-administration of Isoniazid with Laretol Injection 1ml may decrease the effects of Laretol Injection 1ml.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Calcifediol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Laretol Injection 1ml can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Rifapentine with Laretol Injection 1ml may decrease the effects of Laretol Injection 1ml.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Laretol Injection 1ml:
Co-administration of Doxercalciferol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Doxercalciferol with Laretol Injection 1ml can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Laretol Injection 1ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Ergocalciferol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Laretol Injection 1ml can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Amobarbital and Laretol Injection 1ml may decrease the effects of Laretol Injection 1ml.

How to manage the interaction:
Co-administration of Laretol Injection 1ml with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Laretol Injection 1ml and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Laretol Injection 1ml:
Taking Laretol Injection 1ml with Fosphenytoin can reduce the levels and efficacy of Laretol Injection 1ml.

How to manage the interaction:
Taking Laretol Injection 1ml with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Side Effects of Laretol Injection 1ml

  • Nausea
  • Headache
  • Constipation or upset stomach
  • Loss of appetite
  • Dry mouth
  • Pain/discomfort at the injection site

Habit Forming

No

Therapeutic Class

MULTIMINERALS

Laretol Injection 1ml Substitute

Substitutes safety advice

Drug-Diseases Interactions

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CALCITRIOL-1MCGOther cardiac arrhythmias
Severe
CALCITRIOL-1MCGDisorders of mineral metabolism
Severe

Drug-Diseases Interactions

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CALCITRIOL-1MCGOther cardiac arrhythmias
Severe
How does the disease interact with Laretol Injection 1ml:
Vitamin D analogues work to raise serum calcium levels and can make arrhythmias worse, especially in people on cardiac glycosides.

How to manage the interaction:
Laretol Injection 1ml increases serum calcium concentrations and may worsen arrhythmia, particularly in patients receiving cardiac glycosides. Laretol Injection 1ml should be administered cautiously in patients with arrhythmia. Monitoring of serum electrolyte concentrations and cardiac function is advised.
CALCITRIOL-1MCGDisorders of mineral metabolism
Severe
How does the disease interact with Laretol Injection 1ml:
The use of vitamin D analogues like calciferol and ergocalciferol in individuals with hypercalcemia, malabsorption syndrome, or signs of vitamin D toxicity is not advised.

How to manage the interaction:
Serum electrolyte concentration should be corrected prior to therapy and monitored during therapy with Laretol Injection 1ml.
CALCITRIOL-1MCGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Laretol Injection 1ml:
Renal biotransformation of ergocalciferol, cholecalciferol, and calcifediol occurs during metabolic activation. Certain vitamin D analogues' therapeutic and metabolic effects may be affected by renal impairment.

How to manage the interaction:
Renal impairment can alter metabolic and therapeutic activity of certain vitamin D analogs. Alternative vitamin D analogs may be considered in patients with compromised renal function.
CALCITRIOL-1MCGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Laretol Injection 1ml:
In order to maintain proper phosphorus levels and prevent ectopic calcification in individuals with renal impairment, vigilance should be exercised because Laretol Injection 1ml increases inorganic phosphate levels in serum.

How to manage the interaction:
Caution is advised in patients with kidney impairment to maintain adequate phosphorus levels and avoid ectopic calcification.

FAQs

Laretol Injection 1ml contains calcitriol, which works by increasing the amount of calcium in your body. It also helps regulate parathyroid hormone levels. Thus it treats patients with low levels of calcium who are on chronic renal dialysis.

Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions (especially if you have too much calcium or vitamin D in the blood), all medications you are using (especially Burosumab, Vitamin D) and sensitivities or allergic conditions to medicines or foods.

Parenteral therapy should only be used for patients unable to take oral medications or in an emergency clinical situation.

Drug-Drug Interactions Checker List

  • Burosumab
  • DIGOXIN
  • DIGITALIS
  • MILK OF MAGNESIA
  • CALCIUM
  • VITAMIN D
  • SEVELAMER

Disease/Condition Glossary

Hypocalcaemia: Low calcium levels in the blood are referred to as hypocalcaemia. It is most usually caused by vitamin D insufficiency or hypoparathyroidism.

Have a query?

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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Laretol Injection 1ml.

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Pregnancy

Caution

There are no sufficient and well-controlled studies on pregnant women. Laretol Injection 1ml should be used during pregnancy only if the possible advantages outweigh the potential risks to the foetus. Inform your doctor if you are pregnant before receiving this injection.

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Breast Feeding

Caution

Laretol Injection 1ml should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. If Laretol Injection 1ml is used during breastfeeding, your doctor may monitor the serum calcium levels of both mother and the infant.

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Driving

Not applicable

Laretol Injection 1ml does not impact your ability to drive or use machinery.

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Liver

Safe if prescribed

Inform your doctor before receiving the Laretol Injection 1ml if you have a history of liver diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Laretol Injection 1ml.

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Kidney

Safe if prescribed

Inform your doctor before receiving the Laretol Injection 1ml if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Consult your doctor

It is unknown whether Laretol Injection 1ml is safe for children under 12 years old. Please consult your doctor for more information.

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