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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

About Larinate-200 Kit

Larinate-200 Kit belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
 
Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.
 
Take Larinate-200 Kit with food. It is advised to take Larinate-200 Kit for as long as your doctor has prescribed, depending on your medical condition. In some cases, Larinate-200 Kit may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Larinate-200 Kit

Malaria

Medicinal Benefits

Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Larinate-200 Kit belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

Side Effects of Larinate-200 Kit

  • Nausea 
  • Vomiting
  • Dizziness
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fatigue

Directions for Use

Take Larinate-200 Kit with food. Swallow Larinate-200 Kit as a whole with a glass of water; do not chew or crush the tablet. Your doctor will decide how long you need to take Larinate-200 Kit depending on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Larinate-200 Kit if you are allergic to any of its contents. Inform your doctor before taking Larinate-200 Kit if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.

Therapeutic Class

ANTI- MALARIALS

Drug-Drug Interactions

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ArtesunateEluxadoline
Severe
ArtesunateCabozantinib
Severe

Drug-Drug Interactions

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ArtesunateEluxadoline
Severe
How does the drug interact with Larinate-200 Kit:
Taking Larinate-200 Kit with Eluxadoline may significantly increase the blood levels of eluxadoline. This may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Larinate-200 Kit and Eluxadoline, you can take these medicines together if prescribed by a doctor. However, if you experience persistent nausea, vomiting, drowsiness, constipation, stomach tenderness, and upper stomach pain, especially that which worsens after eating or radiates to the back or shoulders, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
ArtesunateCabozantinib
Severe
How does the drug interact with Larinate-200 Kit:
Taking Larinate-200 Kit with Cabozantinib may increase blood levels and effects of Larinate-200 Kit and increase the risk of side effects.

How to manage the interaction:
Although taking Larinate-200 Kit with cabozantinib together can result in an interaction, they can be taken if a doctor has prescribed it. Do not discontinue any medication without consulting a doctor.
ArtesunateAtazanavir
Moderate
How does the drug interact with Larinate-200 Kit:
Atazanavir may increase blood levels of Larinate-200 Kit and increase the risk of side effects such as liver damage, kidney failure, excess bilirubin in the blood, low red blood cell/platelet count and high white blood cell count.

How to manage the interaction:
If you are supposed to take Larinate-200 Kit and Atazanavir together, your doctor may adjust the dose or monitor more frequently to safely use both medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • RITONAVIR
  • NEVIRAPINE
  • RIFAMPIN
  • CHLOROQUINE
  • METHOTREXATE

Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. It helps in preventing the formation of kidney stones.
  • Consume fruits rich in vitamin A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fiber foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/spray.
  • Avoid pickles, alcohol, coffee, tea, carbonated beverages, and spicy food.

Habit Forming

No

Special Advise

  • Regular laboratory tests such as blood tests, liver and kidney function tests while taking Larinate-200 Kit are advised.

Author Details

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Disease/Condition Glossary

Malaria: Malaria is a blood disease spread by the female anopheles mosquito. Malaria is spread through the bite of an infected mosquito carrying the Plasmodium parasite. The parasite is released into the bloodstream when an infected mosquito bites a person. The parasite develops in the liver before infecting red blood cells. It then multiplies in red blood cells, resulting in malarial infection. Malaria symptoms include fever, headache, exhaustion, muscle pain, back pain, chills, sweating, nausea, vomiting, and a dry cough. Symptoms typically appear 10 days to 4 weeks after infection.

Larinate-200 Kit Substitute

Substitutes safety advice
  • Falcigo-SP Kit

    220.50per tablet
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