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Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lazid E Kit

Lazid E Kit belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Lazid E Kit is a combination of three medicines: Efavirenz, zidovudine, and lamivudine. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. Lazid E Kit may cause side effects such as headache, tiredness, dizziness, drowsiness, vomiting, diarrhea, insomnia, nightmare, muscle damage, and anemia (low number of red blood cells). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take Lazid E Kit if you are allergic to any contents of it. Before taking Lazid E Kit, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), a history of mental illness, or are seriously overweight and have kidney disease. Inform your doctor if you are pregnant or breastfeeding. Lazid E Kit should not be given to children below 2 years of age. Lazid E Kit should be used with caution in elderly patients. Alcohol consumption may increase the risk of side effects. Lazid E Kit may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Lazid E Kit

HIV infection

Directions for Use

Take Lazid E Kit with food or after a meal as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Lazid E Kit belongs to the group of medicines called antiretroviral therapy (ART). Lazid E Kit contains efavirenz, zidovudine and lamivudine. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection. It helps in improving the quality of life of a patient with HIV.

 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you develop persistent diarrhea or vomiting, as it may affect the effectiveness of Lazid E Kit. Lazid E Kit may cause pancreatitis (inflammation of the pancreas), so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting, or stomach pain. Lazid E Kit may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat), and tremors. Lazid E Kit may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. Lazid E Kit may also cause dizziness and abnormal heartbeat. Inform your doctor immediately if you notice any significant changes in the electrocardiogram (ECG). Do not take Lazid E Kit if you have severe liver disease, a slow heartbeat, or severe heart disease, a very low red blood cell count (anemia) or a very low white blood cell count (neutropenia). Speak with your doctor about the precautions to follow to avoid infecting other people as one can still pass on HIV while on this medicine, although the risk is somewhat lowered by antiretroviral therapy; it can spread through sexual contact with a person who already has the infection, or by transfer of infected blood. Lazid E Kit does not cure HIV infection. Lazid E Kit can make hormonal contraceptives less effective or less likely to work. So, use other effective methods for contraception, including a barrier form (cervical cap, condom, diaphragm, or contraceptive sponge) to prevent pregnancy while on Lazid E Kit and for at least 12 weeks after stopping treatment as advised by your doctor. Do not breast-feed while taking this medicine. Also, do not take Lazid E Kit with other medicines such as stavudine, used to treat HIV infection, ribavirin or ganciclovir to treat viral infections, rifampicin to treat bacterial infections, bepridil (used to treat heart disease), cisapride (used to treat heartburn), methadone (used to treat opiate addiction), St. John’s wort (Hypericum perforatum) (a herbal remedy used for depression and anxiety), flecainide, metoprolol (used to treat irregular heartbeat). Lazid E Kit is not recommended in pregnancy as could harm the unborn baby or cause birth defects. You may need frequent medical tests while on Lazid E Kit.

Drug-Drug Interactions

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EfavirenzLomitapide
Critical

Drug-Drug Interactions

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How does the drug interact with Lazid E Kit:
Taking Lazid E Kit with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Lazid E Kit with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Lazid E Kit:
When Lazid E Kit is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Lazid E Kit with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lazid E Kit:
Coadministration of Voriconazole with Lazid E Kit can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Lazid E Kit can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lazid E Kit:
When Lazid E Kit is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Lazid E Kit is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Lazid E Kit:
When Lazid E Kit is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Lazid E Kit is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Lazid E Kit:
Taking Lazid E Kit with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Lazid E Kit with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lazid E Kit:
Using ziprasidone together with Lazid E Kit can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Lazid E Kit with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lazid E Kit:
When Lazid E Kit is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Lazid E Kit with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lazid E Kit:
Using carbamazepine together with Lazid E Kit may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Lazid E Kit with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzRilpivirine
Critical
How does the drug interact with Lazid E Kit:
Taking Rilpivirine with Lazid E Kit can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Lazid E Kit together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange and red vegetables, and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 
  • Wash your hands properly before and after eating.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lazid E Kit is a combination of three medicines: Efavirenz, zidovudine, and lamivudine. These three drugs work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection.

Lazid E Kit may cause side-effects such as abnormal dreams, difficulty concentrating, dizziness, blurred vision, whistling, ringing, aching muscles, difficulty in sleeping, hair loss, cough, feeling breathless. Inform your doctor if any of these side-effects persist or get worse.

Lazid E Kit doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Lazid E Kit may cause lactic acidosis (excess of lactic acid in the blood), a rare but a severe side effect, especially in women who are very obese. However, if you experience stomach pain, vomiting or nausea while taking Lazid E Kit, please consult a doctor immediately.

No, Lazid E Kit should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Lazid E Kit, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Do not stop taking Lazid E Kit without talking to your doctor. If you suddenly stop taking Lazid E Kit, you may experience confusion, fever, mental state changes or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

Drug-Drug Interactions Checker List

  • DOXORUBICIN
  • RIBAVIRIN
  • STAVUDINE
  • CLADRIBINE
  • BEPRIDIL
  • CISAPRIDE
  • METHADONE
  • CLOMIPRAMINE
  • EMTRICITABINE

Special Advise

  • Lazid E Kit may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Lazid E Kit should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Lazid E Kit. So, use necessary precautions to avoid infecting others.
  • Lazid E Kit may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

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