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  3. Leekuf-SF Syrup 100 ml

Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Leekuf-SF Syrup 100 ml, Pack of 1 Syrup
Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Whats That

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Composition :

CHLORPHENIRAMINE MALEATE-4MG + DEXTROMETHORPHAN HYDROBROMIDE-10MG + GUAIPHENESIN-100MG + PHENYLEPHRINE HYDROCHLORIDE-5MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Leekuf-SF Syrup

Leekuf-SF Syrup belongs to a class of medications called ‘expectorants’ primarily used to treat dry cough. Additionally, Leekuf-SF Syrup also treats allergy symptoms such as sneezing, runny nose, throat irritation or watery eyes. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Leekuf-SF Syrup is a combination of four drugs, namely: Guaiphenesin (expectorant), Dextromethorphan hydrobromide (cough suppressant), Phenylephrine hydrochloride (decongestant) and Chlorpheniramine maleate (antihistamine). Guaiphenesin belongs to the expectorant class that increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Dextromethorphan hydrobromide is a cough suppressant that works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

Take Leekuf-SF Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Leekuf-SF Syrup based on your medical condition. Some people may experience nausea, stomach upset, vomiting, loss of appetite, drowsiness, headache, diarrhoea, dizziness or skin rash. Most of these side effects of Leekuf-SF Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Leekuf-SF Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Leekuf-SF Syrup . If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Leekuf-SF Syrup . Drink plenty of fluids while taking Leekuf-SF Syrup to loosen the congestion. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath) or chronic obstructive pulmonary disease (COPD) inform your doctor before taking Leekuf-SF Syrup .

Uses of Leekuf-SF Syrup

Dry cough

Directions for Use

Shake the bottle well before use. Check the label for directions and take Leekuf-SF Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Leekuf-SF Syrup contains Guaiphenesin, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, and Chlorpheniramine maleate used to treat dry cough. Guaiphenesin is an expectorant that increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Dextromethorphan hydrobromide is a cough suppressant that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thus, provides relief from congestion and decreases mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please inform your doctor if you are allergic to Leekuf-SF Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Leekuf-SF Syrup . If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Leekuf-SF Syrup . Avoid using Leekuf-SF Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Leekuf-SF Syrup .

Drug-Drug Interactions

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DextromethorphanPhenelzine
Critical
DextromethorphanIsocarboxazid
Critical

Drug-Drug Interactions

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DextromethorphanPhenelzine
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Phenelzine and Leekuf-SF Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Leekuf-SF Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Isocarboxazid with Leekuf-SF Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Leekuf-SF Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanSelegiline
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Leekuf-SF Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Leekuf-SF Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPargyline
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Pargyline and Leekuf-SF Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Leekuf-SF Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Taking Rasagiline with Leekuf-SF Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Leekuf-SF Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Taking Tranylcypromine with Leekuf-SF Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Leekuf-SF Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanProcarbazine
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Leekuf-SF Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Leekuf-SF Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Taking Tranylcypromine with Leekuf-SF Syrup 100 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Leekuf-SF Syrup 100 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Taking Furazolidone with Leekuf-SF Syrup 100 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Leekuf-SF Syrup 100 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Leekuf-SF Syrup 100 ml only after 14 days of stopping Furazolidone.
PhenylephrineSelegiline
Critical
How does the drug interact with Leekuf-SF Syrup 100 ml:
Co-administration of Selegiline with Leekuf-SF Syrup 100 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Leekuf-SF Syrup 100 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Leekuf-SF Syrup contains Guaiphenesin, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Guaiphenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Dextromethorphan hydrobromide is a cough suppressant that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thus, it provides relief from congestion and decreases mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Leekuf-SF Syrup may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Leekuf-SF Syrup contains Chlorpheniramine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

You are not recommended to take Leekuf-SF Syrup with selegiline or other MAO inhibitors such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection at the same time as it may cause severe high blood pressure which may lead to stroke. Therefore, if you have taken any of these medicines in the past 14 days, avoid taking Leekuf-SF Syrup and consult a doctor for proper advice.

You are recommended to avoid taking Leekuf-SF Syrup if you have asthma, enlarged prostate, blockage in stomach or intestines, glaucoma or if you are unable to urinate. However, please consult a doctor if you have any of these conditions before taking Leekuf-SF Syrup .

You are not recommended to take Leekuf-SF Syrup with duloxetine (a drug used to treat peripheral neuropathy) as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Leekuf-SF Syrup with other medicines.

You are recommended to take Leekuf-SF Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Leekuf-SF Syrup , please consult your doctor.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • HYDROCODONE
  • CODEINE
  • ALPRAZOLAM
  • METHYLPHENIDATE
  • QUETIAPINE
  • QUINIDINE
  • PREGABALIN
  • AMPHETAMINE

Special Advise

  • You are recommended to inform your doctor that you are taking Leekuf-SF Syrup before undergoing any medical tests or surgery.
  • Drink plenty of fluids while taking Leekuf-SF Syrup to loosen the congestion of nasal passage and airways. If you are a kidney patient, ask a doctor before taking fluid.

Disease/Condition Glossary

Cough: Coughing is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger, 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.

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