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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Lenshil 4mg Capsule 10's

Lenshil 4mg Capsule 10's is an anti-cancer medicine used in the treatment of various types of cancers. Cancer is a disease caused by the abnormal growth of cells that divide uncontrollably. This medicine is used in treating hepatocellular carcinoma as a first-line therapy, differentiated thyroid cancer in patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory, advanced renal cell carcinoma in combination with pembrolizumab, and advanced endometrial cancer in combination with pembrolizumab.

Lenshil 4mg Capsule 10's contains Lenvatinib, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Lenshil 4mg Capsule 10's may cause certain side effects such as diarrhoea, decreased appetite, nausea, vomiting, tiredness, itching, rash, headache, cough, abdominal pain, hoarseness, and dizziness. Inform your doctor if any of these side effects bother you. Lenshil 4mg Capsule 10's should be taken as prescribed by your doctor. Do not take more than the recommended dose of medicine.

If you are allergic to Lenshil 4mg Capsule 10's or its components, inform your doctor. Before taking Lenshil 4mg Capsule 10's, inform your doctor if you have/had liver or kidney disease, calcium deficiency, heart problems, increased blood pressure, seizures, bleeding disorders, vision problems, and a history of blood clots. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. 

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

LENVATINIB-4MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Lenshil 4mg Capsule 10's

Renal Cell Carcinoma, Hepatocellular carcinoma, Differentiated thyroid cancer, Endometrial cancer.

Medicinal Benefits

Lenshil 4mg Capsule 10's contains Lenvatinib, which is used in treating different types of cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Lenshil 4mg Capsule 10's stops the body's production, spread and growth of cancerous cells.

Side Effects of Lenshil 4mg Capsule 10's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Muscle/joint pain
  • Dizziness
  • Weakness
  • Cough
  • Headache
  • Itching
  • Rash
  • Decreased weight
  • Abdominal pain
  • Vision problem

Directions for Use

Take Lenshil 4mg Capsule 10's as prescribed by the doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not crush, break, or chew it. It is advised not to take more than the recommended dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

To treat your condition effectually, continue taking Lenshil 4mg Capsule 10's for the period that your doctor has prescribed. Avoid taking Lenshil 4mg Capsule 10's if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, stroke, blood or bleeding disorders, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established. Lenshil 4mg Capsule 10's may cause hypertension, thrombotic events, hemorrhagic events, hypothyroidism, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), elevated liver enzymes, kidney impairment, hypocalcemia, wound healing problems, and osteonecrosis in some patients. Hence, inform your doctor about your complete medication and medical history before taking Lenshil 4mg Capsule 10's.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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LenvatinibThioridazine
Critical
LenvatinibHalofantrine
Critical

Drug-Drug Interactions

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LenvatinibThioridazine
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and Thioridazine together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Using Lenshil 4mg Capsule 10's and Thioridazine is not recommended, but they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibHalofantrine
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and Halofantrine together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Lenshil 4mg Capsule 10's and Halofantrine together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibSparfloxacin
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and Sparfloxacin together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Using Lenshil 4mg Capsule 10's and Sparfloxacin is not recommended, but they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibGrepafloxacin
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Coadministration of grepafloxacin and Lenshil 4mg Capsule 10's can increase the risk irregular heart rhythm.

How to manage the interaction:
Although using Lenshil 4mg Capsule 10's and Grepafloxacin together is not recommended as it can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
LenvatinibPimozide
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Coadministration of Lenshil 4mg Capsule 10's with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although using Lenshil 4mg Capsule 10's and Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibMesoridazine
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's with Mesoridazine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Lenshil 4mg Capsule 10's and mesoridazine, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LenvatinibZiprasidone
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Lenshil 4mg Capsule 10's and Ziprasidone together is not recomended as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibSaquinavir
Critical
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Lenshil 4mg Capsule 10's and Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibCrizotinib
Severe
How does the drug interact with Lenshil 4mg Capsule 10's:
Taking Lenshil 4mg Capsule 10's and crizotinib together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Lenshil 4mg Capsule 10's and Crizotinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, it's important to call your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenvatinibNilotinib
Severe
How does the drug interact with Lenshil 4mg Capsule 10's:
Using nilotinib together with Lenshil 4mg Capsule 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Lenshil 4mg Capsule 10's and Nilotinib, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • EFAVIRENZ
  • TERIFLUNOMIDE
  • SPARFLOXACIN
  • MOXIFLOXACIN

Diet & Lifestyle Advise

  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Habit Forming

No

Special Advise

  • Your doctor may suggest periodic liver function tests, kidney function tests, lung function tests and urine tests to monitor the function of the liver, kidney, lungs and the presence of protein in urine due to the use of Lenshil 4mg Capsule 10's.
  • Using contraceptive pills while using Lenshil 4mg Capsule 10's to prevent pregnancy is advised.
  • Thyroid function and adrenocorticotropic hormone levels will be monitored during treatment to avoid any life-threatening side effects.
  • It is advised to use contraceptive pills while using Lenshil 4mg Capsule 10's to prevent pregnancy.
  • Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing, as it may be a sign of a heart problem.

Disease/Condition Glossary

Renal Cell Carcinoma: Also known as kidney cancer. It is the most common type of cancer seen in adults. This condition occurs when cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Advanced kidney cancer (metastatic renal cell carcinoma) occurs when the malignant cells spread to other parts of the body. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine.

Hepatocellular carcinoma: Also known as liver cancer. It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions.

Differentiated Thyroid cancer: This condition occurs when the cancer cells grow abnormally in the thyroid gland. The thyroid gland is a butterfly-shaped organ present under the neck. This gland is useful in producing hormones responsible for the functioning of the body. Differentiated thyroid cancer is the most common type of thyroid carcinoma, which includes papillary thyroid cancer and follicular thyroid cancer.

Endometrial cancer: It is a cancer which affects the endometrium (lining of the womb or uterus). Symptoms may include bleeding between periods, pelvic pain, and pain during sexual intercourse. This cancer mostly occurs due to certain factors such as increasing age, obesity, never being pregnant, family history of cancer, and diabetes. It is usually seen in women above the age of 55 years. This condition is not life-threatening when it is diagnosed and treated in the early stages.

Lenshil 4mg Capsule 10's Substitute

Substitutes safety advice
  • Lenvima 4 mg Capsule 10's

    by AYUR

    965.14per tablet
  • Lenvatol 4 Capsule 10's

    167.81per tablet
  • Lenvenib 4 mg Capsule 7's

    157.50per tablet
  • Lenvat 4 Capsule 30's

    82.00per tablet
  • Lentykine 4 mg Capsule 10's

    by AYUR

    135.00per tablet
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