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  3. Lepromine 100mg Capsule

Lepromine 100mg Capsule, Pack of 1 Capsule
Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Composition :

CLOFAZIMINE-100MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lepromine 100mg Capsule

Lepromine 100mg Capsule belongs to the group of medicines called antileprotic drugs primarily used to treat Leprosy (infectious disease-causing skin lesions and nerve damage). Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae, which is a chronic infectious disease. The illness mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.

Clofazimine is the active component in Lepromine 100mg Capsule. It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, Lepromine 100mg Capsule aids in the treatment of Leprosy.

Take Lepromine 100mg Capsule daily at the same time to ensure better efficacy. The dose and duration of Lepromine 100mg Capsule can vary depending upon your condition and the severity of the infection. In some situations, you may experience symptoms such as stomach and epigastric pain, diarrhoea, nausea, and vomiting. These negative impacts do not necessitate medical treatment and will gradually subside. However, if you are experiencing these undesirable effects frequently, you should consult your doctor.

Continue using Lepromine 100mg Capsule for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Lepromine 100mg Capsule. Lepromine 100mg Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Lepromine 100mg Capsule. If pregnant or breastfeeding, consult your doctor before using Lepromine 100mg Capsule. Do not use Lepromine 100mg Capsule in more than specified doses or for an extended time. Before taking Lepromine 100mg Capsule, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects.

Uses of Lepromine 100mg Capsule

Leprosy

Directions for Use

Chew the tablet completely and swallow. Do not swallow it as a whole.

Medicinal Benefits

Lepromine 100mg Capsule contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe Lepromine 100mg Capsule to treat various bacterial infections due to Mycobacterium.

Storage

Store in a cool and dry place away from sunlight
Side effects of Lepromine 100mg Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid triggering foods like spicy and fatty foods.
  • Eat smaller meals and digestible foods.
  • Regular exercise can improve gastrointestinal health.
  • Avoid sleeping immediately after eating as it can worsen digestion and lead to discomfort.
  • Drink plenty of water to stay hydrated.
  • Manage stress through relaxation techniques.
  • Moisturize often with creams or lotions.
  • Take long, warm baths to soften scales.
  • Gently scrub dry skin with a soft sponge to exfoliate your skin.
  • Apply petroleum jelly to deep cracks.
  • Avoid itching, apply cool compresses, use gentle soaps and watch for redness and swelling.
  • See a doctor for management if your condition persists.

Drug Warnings

Continue using Lepromine 100mg Capsule for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Lepromine 100mg Capsule. Lepromine 100mg Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Lepromine 100mg Capsule. If pregnant or breastfeeding, consult your doctor before using Lepromine 100mg Capsule. Do not use Lepromine 100mg Capsule in more than specified doses or for an extended time. Before taking Lepromine 100mg Capsule, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects. Sun lamps should be avoided. Clofazimine may increase your skin's sensitivity to sunlight or sunlamps. Therefore, wear protective clothing when exposed to direct sunlight and apply sunscreen with an SPF of at least 15.

Drug-Drug Interactions

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ClofazimineDofetilide
Critical
ClofazimineThioridazine
Critical

Drug-Drug Interactions

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ClofazimineDofetilide
Critical
How does the drug interact with Lepromine 100mg Capsule:
When Lepromine 100mg Capsule is taken with Dofetilide, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Dofetilide is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineThioridazine
Critical
How does the drug interact with Lepromine 100mg Capsule:
When Lepromine 100mg Capsule is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Thioridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineMesoridazine
Critical
How does the drug interact with Lepromine 100mg Capsule:
When Lepromine 100mg Capsule is taken with Mesoridazine, it can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Mesoridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineZiprasidone
Critical
How does the drug interact with Lepromine 100mg Capsule:
Taking Lepromine 100mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Ziprasidone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDronedarone
Critical
How does the drug interact with Lepromine 100mg Capsule:
When Lepromine 100mg Capsule is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Dronedarone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineCisapride
Critical
How does the drug interact with Lepromine 100mg Capsule:
When Lepromine 100mg Capsule is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Lepromine 100mg Capsule with Cisapride is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineChloroquine
Severe
How does the drug interact with Lepromine 100mg Capsule:
Co-administration of chloroquine with Lepromine 100mg Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking chloroquine and Lepromine 100mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineProcainamide
Severe
How does the drug interact with Lepromine 100mg Capsule:
Co-administration of procainamide with Lepromine 100mg Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking procainamide with Lepromine 100mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineArsenic trioxide
Severe
How does the drug interact with Lepromine 100mg Capsule:
Co-administration of arsenic trioxide with Lepromine 100mg Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking arsenic trioxide with Lepromine 100mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineCabozantinib
Severe
How does the drug interact with Lepromine 100mg Capsule:
Co-administration of cabozantinib with Lepromine 100mg Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking cabozantinib with Lepromine 100mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach and blueberries.
  • Consuming food rich in probiotics helps develop the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoid getting in contact with harsh soaps, detergents and rough fabrics.

Habit Forming

No

Therapeutic Class

ANTILEPROTICS

Lepromine 100mg Capsule Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lepromine 100mg Capsule contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe Lepromine 100mg Capsule treat various bacterial infections due to Mycobacterium.

Drug-Drug Interactions Checker List

  • AZITHROMYCIN
  • TRIMETHOPRIM
  • SULFAMETHOXAZOLE
  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • SIMETHICONE

Disease/Condition Glossary

Leprosy: Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae. It is a chronic infectious disease that mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.

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