Letfirst Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Letfirst Tablet 5's contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Letfirst Tablet 5's prevents the growth of cancer cells. Thereby Letfirst Tablet 5's helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Letfirst Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Letfirst Tablet 5's may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Letfirst Tablet 5's if you are pregnant or breastfeeding. Letfirst Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Letfirst Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Letfirst Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Letfirst Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors. Letfirst Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of periods). Letfirst Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Letfirst Tablet 5's prevents the growth of cancer cells. Thereby, Letfirst Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

• Hypercholesterolemia (increased cholesterol levels)
• Tiredness
• Weakness
• Increased sweating
• Feeling unwell
• Pain in joints
• Hot flushes (feeling of warmth)

Do not take Letfirst Tablet 5's if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Letfirst Tablet 5's if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Letfirst Tablet 5's may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Letfirst Tablet 5's. Avoid taking Letfirst Tablet 5's if you are pregnant or breastfeeding. Letfirst Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Letfirst Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Letfirst Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Letfirst Tablet 5's to rule out any side-effects. 

Drug-Drug Interactions: Letfirst Tablet 5's may interact with antidepressants (citalopram, escitalopram) and anticancer (tamoxifen). 

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have high cholesterol, osteoporosis (thinning of bone), or liver disease.

• CITALOPRAM
• ESCITALOPRAM
• TAMOXIFEN

• Eat a healthy diet and exercise regularly to maintain proper weight.
• Avoid smoking and alcohol consumption.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
• Avoid fast food, fried food, processed meats, refined carbs and added sugar.
• Get optimal sleep; rest well.

• Your doctor may advise you to regularly measure bone density before, during and after the treatment as Letfirst Tablet 5's may cause bone thinning due to reduction of estrogens in the body.
• Letfirst Tablet 5's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Letfirst Tablet 5's.

Breast cancer: It is a type of cancer that develops in breast cells which are stimulated by the female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.