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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

LETROZOLE-2.5MG

Manufacturer/Marketer :

UFirst Pharmaceutical Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Letfirst Tablet 5's

Letfirst Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Letfirst Tablet 5's contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Letfirst Tablet 5's prevents the growth of cancer cells. Thereby Letfirst Tablet 5's helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Letfirst Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Letfirst Tablet 5's may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Letfirst Tablet 5's if you are pregnant or breastfeeding. Letfirst Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Letfirst Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Letfirst Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Letfirst Tablet 5's

Breast cancer

Directions for Use

Take Letfirst Tablet 5's with or without food. Swallow Letfirst Tablet 5's as a whole with a glass of water; do not chew or break it. Take Letfirst Tablet 5's at the same time every day.

Medicinal Benefits

Letfirst Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors. Letfirst Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of periods). Letfirst Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Letfirst Tablet 5's prevents the growth of cancer cells. Thereby, Letfirst Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Storage

Store in a cool and dry place away from sunlight
Side effects of Letfirst Tablet
  • Consult your doctor about your risk factors for bone loss and create a personalized plan.
  • Eat foods rich in vitamin D, including fatty fish, egg yolks, and fortified dairy products.
  • Include calcium-rich foods such as dairy, leafy greens, and fortified plant-based milk in your diet.
  • Quit smoking to reduce bone loss and lower osteoporosis risk.
  • Exercise regularly with weight-bearing activities like walking, running, or weightlifting to strengthen bones.
  • Schedule regular bone density scans to track progress and adjust your treatment plan.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Drug Warnings

Do not take Letfirst Tablet 5's if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Letfirst Tablet 5's if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Letfirst Tablet 5's may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Letfirst Tablet 5's. Avoid taking Letfirst Tablet 5's if you are pregnant or breastfeeding. Letfirst Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Letfirst Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Letfirst Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Letfirst Tablet 5's to rule out any side-effects. 

Drug-Drug Interactions

verifiedApollotooltip
LetrozoleEstradiol
Severe
LetrozoleEstramustine
Severe

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Letfirst Tablet 5's Substitute

Substitutes safety advice
  • Letroz Tablet 5's

    by Others

    29.52per tablet
  • Letroz Tablet 30's

    by AYUR

    29.54per tablet
  • Femara 2.5 mg Tablet 10's

    by Others

    28.86per tablet
  • Letoval Tablet 5's

    by Others

    29.52per tablet
  • Fempro Tablet 10's

    by Others

    8.01per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Letfirst Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Letfirst Tablet 5's prevents the growth of cancer cells. Thereby, Letfirst Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Letfirst Tablet 5's causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Letfirst Tablet 5's. Regularly monitor blood pressure levels while taking Letfirst Tablet 5's. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Letfirst Tablet 5's on your own. You are advised to take Letfirst Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Letfirst Tablet 5's.

Letfirst Tablet 5's may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Letfirst Tablet 5's.

Letfirst Tablet 5's may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Letfirst Tablet 5's may cause bone thinning due to reduction of estrogens in the body.
  • Letfirst Tablet 5's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Letfirst Tablet 5's.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells which are stimulated by the female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.  

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