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  3. Leucorin Tablet 10's

Leucorin Tablet 10's, Pack of 10 TABLETS
Leucorin Tablet 10's, Pack of 10 TABLETS
Leucorin Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Synonym :

LEUCOVORIN

Composition :

CALCIUM FOLINATE-15MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Leucorin Tablet

Leucorin Tablet belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cancer treatment as an antidote to reduce the toxic effects of certain cancer drugs, such as methotrexate. Besides this, it can also use in combination with 5-fluorouracil in cancer treatment (cytotoxic therapy).

Leucorin Tablet contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

Use Leucorin Tablet as advised by a qualified healthcare professional. You may experience nausea, diarrhoea, rash, vomiting, itching, urticaria or hives and stomatitis (oral mucositis). Most of these side effects of Leucorin Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Before taking the Leucorin Tablet , let your doctor know if you are allergic to any ingredient in it. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding or if you have pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment and seizures.

Uses of Leucorin Tablet

Prevention of harmful effects of methotrexate

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Leucorin Tablet belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cytotoxic therapy as an antidote to reduce the toxicity and effect of certain cancer drugs such as methotrexate. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (or other cancer medicines) while accepting it to enter and kill the cancer cells. Besides this, it can also use in combination with the drug 5-fluorouracil in cancer treatment (cytotoxic therapy).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Leucorin Tablet , inform your doctor if you are allergic to any of its ingredients. If you are pregnant, planning to become pregnant, or breastfeeding, or if you have pernicious anaemia or other kinds of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment, or seizures, please notify your doctor. Inform your doctor about your medical history and current drugs to rule out potential side effects.

Drug-Drug Interactions

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Calcium folinateTrimethoprim
Severe

Drug-Drug Interactions

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Calcium folinateTrimethoprim
Severe
How does the drug interact with Leucorin Tablet:
Co-administration of Leucorin Tablet with Trimethoprim may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between Leucorin Tablet and trimethoprim, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
  • Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid taking Leucorin Tablet with alcohol as there may be an interaction.
  • Avoid tobacco use.

Habit Forming

No

Therapeutic Class

DETOXIFYING AGENTS

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:48 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Leucorin Tablet contains calcium folinate, also known as Leucovorin. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells.

Leucorin Tablet is an antidote to the side effects of various chemotherapy medications, such as methotrexate.

Leucorin Tablet is contraindicated to use in populations with pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency.

It is contraindicated to use if you are known for hypersensitivity to any components present in Leucorin Tablet or if you have Pernicious anaemia or other anaemias due to vitamin B12 deficiency.

Drug-Drug Interactions Checker List

  • FLUOROURACIL
  • CAPECITABINE
  • PAFOLACIANINE
  • TRIMETHOPRIM
  • CEFTRIAXONE

Disease/Condition Glossary

Harmful effects of methotrexate: Methotrexate treats cancer, severe rheumatoid arthritis, and severe psoriasis. It can cause side effects like swollen gums, headaches, hair loss, dizziness, etc. Sometimes, it can cause fatal side effects. Harmful effects of methotrexate include vision loss, seizures/ fits, loss of consciousness, etc. It can damage the blood, liver, bone marrow, lungs, etc. The drug can lead to birth defects and death in unborn babies.

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