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Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Composition :

LEUPRORELIN-11.25MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Leugard 11.25 Depot Injection

Leugard 11.25 Depot Injection belongs to the class of synthetic hormones used in the treatment of prostate cancer in men, endometriosis, and hormone-responsive breast cancer in women. Also, Leugard 11.25 Depot Injection is used to treat premature puberty in children. Prostate cancer is cancer of the prostate gland (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Leugard 11.25 Depot Injection contains Leuprorelin, a synthetic hormone that works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and estrogen in women. Thereby, Leugard 11.25 Depot Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumor or causing it to shrink.  

Use Leugard 11.25 Depot Injection as prescribed by your doctor. You are advised to take Leugard 11.25 Depot Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience pain, redness, swelling, or skin hardening at the injection site, muscle weakness, bone pain, inability to have an erection, breast tenderness, headache, vaginal dryness, changes in breast size, acne, or mood swings. Most of these side effects of Leugard 11.25 Depot Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Leugard 11.25 Depot Injection or any other medicines, please tell your doctor. Leugard 11.25 Depot Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective contraceptive measures to avoid pregnancy while taking Leugard 11.25 Depot Injection as it may cause birth defects. Leugard 11.25 Depot Injection should be used with caution in children. You are recommended to avoid or limit consumption of alcohol with Leugard 11.25 Depot Injection as it may increase the risk of bone density loss. Drive only if you are alert as Leugard 11.25 Depot Injection may cause dizziness, drowsiness, or vision disturbances.

Uses of Leugard 11.25 Depot Injection

Prostate cancer, Breast cancer, Endometriosis, Premature puberty

Directions for Use

Leugard 11.25 Depot Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Leugard 11.25 Depot Injection contains Leuprorelin which works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and oestrogen in women. Thereby, Leugard 11.25 Depot Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumour or causing it to shrink.  Also, Leugard 11.25 Depot Injection is used to treat hormone-responsive breast cancer in pre and postmenopausal women. By reducing testosterone and oestrogen levels, Leugard 11.25 Depot Injection delays the onset of puberty in children.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Leugard 11.25 Depot Injection or any other medicines, please tell your doctor. Leugard 11.25 Depot Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Leugard 11.25 Depot Injection as it may cause birth defects. Leugard 11.25 Depot Injection should be used with caution in children. You are advised to quit smoking as it may increase the risk of prostate cancer. You are recommended to avoid or limit consumption of alcohol with Leugard 11.25 Depot Injection as it may increase the risk of bone density loss. Drive only if you are alert as Leugard 11.25 Depot Injection may cause dizziness, drowsiness or vision disturbances.

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
LeuprorelinNilotinib
Critical

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Leugard 11.25 Depot Injection with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinNilotinib
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinIbutilide
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCitalopram
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Coadministration of Leugard 11.25 Depot Injection and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking Leugard 11.25 Depot Injection with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinPimozide
Critical
How does the drug interact with Leugard 11.25 Depot Injection:
Taking Leugard 11.25 Depot Injection with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Leugard 11.25 Depot Injection with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinHaloperidol
Severe
How does the drug interact with Leugard 11.25 Depot Injection:
Co-administration of Leugard 11.25 Depot Injection with Haloperidol can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Although taking Leugard 11.25 Depot Injection and haloperidol together may lead to an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, and saturated fat found in animal products, milk, and dairy products as they may increase the risk of prostate cancer.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.

Habit Forming

No

Therapeutic Class

GONADOTROPHIN-RELEASING HORMONE AGONIST

Leugard 11.25 Depot Injection Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Leugard 11.25 Depot Injection contains Leuprorelin, a synthetic hormone that works similar to the natural hormone, gonadotropin-releasing hormone (GnRH) by acting on the pituitary gland and decreases the levels of testosterone in men and oestrogen in women. Thereby, Leugard 11.25 Depot Injection is used in the treatment of prostate cancer by inhibiting the growth of tumour or causing it to shrink.

Leugard 11.25 Depot Injection may stop menstrual periods. However, after 7 to 12 weeks of taking the final dose of injection, periods will resume. Please consult a doctor if you have any concerns regarding this.

Leugard 11.25 Depot Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Leugard 11.25 Depot Injection and inform your doctor if you have diabetes before taking Leugard 11.25 Depot Injection.

Leugard 11.25 Depot Injection may be used to treat endometriosis (tissue lining the uterus known as endometrium grows outside the uterus). Leugard 11.25 Depot Injection reduces oestrogen levels and causes menopause temporarily. Thereby, shrink the tissue outside the uterus or stop its growth.

Leugard 11.25 Depot Injection may decrease bone density, especially when used for the treatment of premature puberty in children. Therefore, regular monitoring of bone density is recommended while taking Leugard 11.25 Depot Injection.

Leugard 11.25 Depot Injection should be used with extreme caution in patients suffering from depression as it may worsen the condition. Therefore, inform your doctor if you have any history of depression before taking Leugard 11.25 Depot Injection.

Drug-Drug Interactions Checker List

  • MOXIFLOXACIN
  • PROCAINAMIDE
  • QUINIDINE
  • SOTALOL
  • AMIODARONE
  • METHADONE
  • CLOZAPINE

Special Advise

Leugard 11.25 Depot Injection may cause changes in blood cholesterol levels or affect values in liver functioning tests. Therefore, inform your doctor that you are taking Leugard 11.25 Depot Injection before undergoing any tests.

Disease/Condition Glossary

Prostate cancer: It is the cancer of the prostate gland (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems. Certain factors increase the risk of prostate cancer, such as the family history of prostate cancer, older age, obesity, or genetic changes.

Breast cancer: It is a type of cancer that develops in breast cells that are stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast.

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse, or discomfort with bowel movements.  

Premature puberty: It is a condition in which the signs of puberty (physical changes in which a child’s body matures into an adult body) start early in children, i.e., before 9 years in girls and before 10 years in boys.

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