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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Levo-Anawin 0.25% Inj 20Ml

Levo-Anawin 0.25% Inj 20Ml belongs to the class of 'local anaesthetics', primarily used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It produces local numbness and relieves pain. Levo-Anawin 0.25% Inj 20Ml is given in the form of an epidural injection at the spinal cord to prevent pain during labour and Caesarean section. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or intermittent. The tolerance level of pain might vary from person to person.

Levo-Anawin 0.25% Inj 20Ml contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Levo-Anawin 0.25% Inj 20Ml helps in numbing the area and provides relief from pain.

Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Levo-Anawin 0.25% Inj 20Ml include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Levo-Anawin 0.25% Inj 20Ml. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using Levo-Anawin 0.25% Inj 20Ml. Levo-Anawin 0.25% Inj 20Ml causes drowsiness, so do not drive until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects like drowsiness. Levo-Anawin 0.25% Inj 20Ml is not recommended for children less than one year of age.

Uses of Levo-Anawin 0.25% Inj 20Ml

Temporary pain relief.

Directions for Use

Levo-Anawin 0.25% Inj 20Ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Levo-Anawin 0.25% Inj 20Ml contains 'Bupivacaine,' a local anaesthetic used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Levo-Anawin 0.25% Inj 20Ml helps in numbing the localized area and provides relief from pain. Levo-Anawin 0.25% Inj 20Ml, when injected as an epidural injection at the spinal cord, it prevents pain during labour and Caesarean section.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Levo-Anawin 0.25% Inj 20Ml

  • Weakness
  • Numbness or tingling
  • Restlessness
  • Drowsiness
  • Tremors or shakiness
  • Headache
  • Blurred vision
  • Irregular heartbeat
  • Hypotension
  • Chills or shivering
  • Back pain
  • Nausea
  • Vomiting 

Drug Warnings

Brief your medical history to the doctor if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs before starting Levo-Anawin 0.25% Inj 20Ml. Let your doctor know if you use any prescription and non-prescription medications, including vitamins and herbal supplements, before starting Levo-Anawin 0.25% Inj 20Ml. Levo-Anawin 0.25% Inj 20Ml may affect the foetus when used by a pregnant mother. It is also released into breast milk during breastfeeding. Please consult your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Levo-Anawin 0.25% Inj 20Ml causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Levo-Anawin 0.25% Inj 20Ml is not recommended in children younger than one year of age.

Drug-Drug Interactions

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LevobupivacainePhenazopyridine
Severe
LevobupivacaineNitrofurantoin
Severe

Drug-Drug Interactions

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LevobupivacainePhenazopyridine
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking phenazopyridine with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a drug interaction between phenazopyridine and Levo-Anawin 0.25% Inj 20Ml but can be taken together if advised by a doctor. If experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, fast breathing, fast heartbeat, anxiety and confusion contact doctor immediately. Do not discontinue medications without consulting a doctor.
LevobupivacaineNitrofurantoin
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Combining Nitrofurantoin with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
There may be a possibility of interaction between Nitrofurantoin and Levo-Anawin 0.25% Inj 20Ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a condition called methemoglobinemia, problems with your heart or lungs, your skin turning gray, feeling sick to your stomach, having a headache, feeling dizzy or lightheaded, being very tired, having trouble breathing, breathing quickly or not deeply enough, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not stop using any medications without a doctor's advice.
LevobupivacaineCyclophosphamide
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Co-administration of Cyclophosphamide with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.25% Inj 20Ml with Cyclophosphamide can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
LevobupivacaineTrimethoprim
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Trimethoprim with Levo-Anawin 0.25% Inj 20Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.25% Inj 20Ml and Trimethoprim, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.
LevobupivacaineDapsone
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Dapsone with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (A condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Levo-Anawin 0.25% Inj 20Ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
LevobupivacaineGlyceryl trinitrate
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Coadministration of Levo-Anawin 0.25% Inj 20Ml and glyceryl trinitrate can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Levo-Anawin 0.25% Inj 20Ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
LevobupivacaineHydroxycarbamide
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Levo-Anawin 0.25% Inj 20Ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Levo-Anawin 0.25% Inj 20Ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
LevobupivacaineBupivacaine
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
C0administration of bupivacaine with Levo-Anawin 0.25% Inj 20Ml can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
There may be a possibility of interaction between Bupivacaine and Levo-Anawin 0.25% Inj 20Ml, but it can be taken if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without a doctor's advice.
LevobupivacaineSulfasalazine
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Coadministration of Levo-Anawin 0.25% Inj 20Ml with Sulfasalazine can increase the risk of methemoglobinemia (a rare red blood cell disorder).

How to manage the interaction:
Taking Levo-Anawin 0.25% Inj 20Ml with Sulfasalazine together can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray discoloration, nausea, headache, dizziness, fatigue, or shortness of breath, it's best to contact a doctor right away. They can help determine the cause and provide appropriate treatment. Do not discontinue any medications without consulting a doctor.
LevobupivacainePhenobarbital
Severe
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Phenobarbital with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.25% Inj 20Ml and Phenobarbital, you can take these medicines together if prescribed by a doctor. Seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the painful areas for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LIDOCAINE
  • AMIODARONE
  • MEXILETINE
  • ASPIRIN
  • ATENOLOL
  • BISOPROLOL

Special Advise

  • Let your doctor know that you are taking Levo-Anawin 0.25% Inj 20Ml if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since Levo-Anawin 0.25% Inj 20Ml may affect your blood pressure.

Disease/Condition Glossary

Pain is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or intermittent. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

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