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Reviewed By Sunny S , MBBS
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About Levotiz Plus Syrup

Levotiz Plus Syrup is a cough and cold medication primarily used to treat the allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. This virus attacks the body through the mouth, nose, or eyes and spreads easily through droplets in the air when a person who is sick sneezes, coughs, or talks.

Levotiz Plus Syrup is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Take Levotiz Plus Syrup with or without food as prescribed by your doctor. Do not crush, chew, or break it. If Levotiz Plus Syrup is in syrup form, measure it with a measuring cup. Your doctor will recommend how often you take Levotiz Plus Syrup based on your medical condition. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Most of these side effects of Levotiz Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Levotiz Plus Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Levotiz Plus Syrup. It should be used with caution in children only if prescribed by a doctor. If you have high blood pressure, kidney or liver problems, coronary artery disease (heart problems), or receiving any monoamine oxidase inhibitor (MAO) therapy to treat depression like Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine etc., inform your doctor before taking Levotiz Plus Syrup. Do not drink alcohol with Levotiz Plus Syrup as it may potentiate the dizziness property of Cetrizine. Hence, it is advisable not to drive or operate heavy machinery or do hazardous work, which requires mental alertness. Taking more than 4 gm per day of paracetamol can damage your liver severely, so if have liver problems, please contact your doctor.

Uses of Levotiz Plus Syrup

Allergies, Common cold

Directions for Use

Tablet/capsule: Take this medicine as prescribed by your doctor. Take it with or without food and swallow it whole with a glass of water. Do not crush, chew, or break it.Oral suspension: Shake the bottle well before use. Check the label for directions and consume in doses as prescribed by a doctor with a measuring cup.

Medicinal Benefits

Levotiz Plus Syrup is primarily used to treat common cold symptoms and reduces symptoms of allergies. It is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Storage

Keep Levotiz Plus Syrup out of the sight and reach of children.

Drug Warnings

Do not take Levotiz Plus Syrup if you are allergic to Levotiz Plus Syrup or any of its ingredients, are pregnant or breastfeeding before starting Levotiz Plus Syrup. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Levotiz Plus Syrup as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Levotiz Plus Syrup. Do not stop taking Levotiz Plus Syrup even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Levotiz Plus Syrup may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Levotiz Plus Syrup if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Levotiz Plus Syrup:
Taking Furazolidone with Levotiz Plus Syrup can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Levotiz Plus Syrup is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Levotiz Plus Syrup only after 14 days of stopping Furazolidone.
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Levotiz Plus Syrup with Sevoflurane can increase the levels of Levotiz Plus Syrup and lead to side effects.

How to manage the interaction:
Taking Levotiz Plus Syrup with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Selegiline with Levotiz Plus Syrup together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Levotiz Plus Syrup is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levotiz Plus Syrup:
Taking Tranylcypromine with Levotiz Plus Syrup can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Levotiz Plus Syrup is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levotiz Plus Syrup:
Taking Levotiz Plus Syrup with Propofol may lead to increased levels of Levotiz Plus Syrup leading to side effects like high blood pressure.

How to manage the interaction:
Taking Levotiz Plus Syrup with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
LevocetirizineEsketamine
Severe
How does the drug interact with Levotiz Plus Syrup:
Using esketamine together with Levotiz Plus Syrup may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Levotiz Plus Syrup with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
PhenylephrineErgotamine
Severe
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Ergotamine and Levotiz Plus Syrup, can raise the risk of side effects including high blood pressure.

How to manage the interaction:
Although taking Levotiz Plus Syrup and Ergotamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of your fingers or toes, pale or cold skin, tightness in your chest, a severe headache, breathing difficulty, irregular heartbeat, vision disturbances, confusion, unclear speech, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Nortriptyline with Levotiz Plus Syrup may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Nortriptyline and Levotiz Plus Syrup together can result in an interaction, it can be taken if a doctor has prescribed it. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.
PhenylephrineIsocarboxazid
Severe
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Levotiz Plus Syrup with Isocarboxazid can result in extremely high blood pressure which may be serious.

How to manage the interaction:
Although taking Isocarboxazid and Levotiz Plus Syrup together can result in an interaction. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Levotiz Plus Syrup:
Co-administration of Levotiz Plus Syrup with Procarbazine raises blood pressure excessively which may show serious effects.

How to manage the interaction:
Although taking Levotiz Plus Syrup and Procarbazine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health. 
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Levotiz Plus Syrup as it may cause tiredness, drowsiness, or lack of concentration.

Side Effects of Levotiz Plus Syrup

  • Drowsiness
  • Headache
  • Tiredness
  • Stomach upset
  • Restlessness
  • Dry mouth

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Levotiz Plus Syrup Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Levotiz Plus Syrup is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

No, you are not recommended to stop taking Levotiz Plus Syrup without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Levotiz Plus Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Levotiz Plus Syrup, please consult your doctor.

No, you should not take Levotiz Plus Syrup along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Levotiz Plus Syrup.

Yes, Cetirizine present in Levotiz Plus Syrup may cause drowsiness. It is not necessary for everyone taking Levotiz Plus Syrup to experience this side effect. Therefore, avoid driving and drinking alcohol if you feel drowsy after taking Levotiz Plus Syrup.

No, you are not recommended to consume alcohol with Levotiz Plus Syrup as it may increase drowsiness, dizziness, and lack of concentration.

No, you are not recommended to take Levotiz Plus Syrup with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • CHLORAMPHENICOL
  • CHOLESTYRAMINE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • PANTOPRAZOLE
  • ISOCARBOXAZID
  • RASAGILINE
  • LINEZOLID
  • TRANYLCYPROMINE

Special Advise

  • Gargle with salt water for relief from sore throat.
  • Close liver monitoring is required especially if people with liver problems are using Levotiz Plus Syrup.
  • For people who have high blood pressure, if prescribed Levotiz Plus Syrup, you should regularly monitor your blood pressure.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by viruses, mainly 'rhinovirus' affecting your nose and throat (upper respiratory tract). Children younger than 6 years of age are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like dust, pollutants, etc. Symptoms of a common cold might include stuffy or runny nose, sore throat, cough, congestion, mild body pain or a mild headache, sneezing, low-grade fever, feeling unwell (malaise). In some cases, the discharge from your nose may become thicker and yellow or green, which is not an indication of a bacterial infection.

Allergies: This occur when your body is attacked or invaded by allergy causing agents known as 'allergens'. These allergens cause our body to release a chemical messenger called as 'histamine which causes inflammation, redness, itchiness, stuffy nose, watery eyes, etc. Allergies can caused due to chemicals, air pollution, pet danders, pollens of plant, seasonal allergies like hay fever.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol with Levotiz Plus Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Levotiz Plus Syrup.

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Pregnancy

Caution

The safety of Levotiz Plus Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Levotiz Plus Syrup in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Levotiz Plus Syrup may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Levotiz Plus Syrup.

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Liver

Caution

Take Levotiz Plus Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Levotiz Plus Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Levotiz Plus Syrup is not recommended for children below 12 years of age. However, please consult a doctor before giving Levotiz Plus Syrup to children.

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