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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Indoco Remedies Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Lignox 2% A Injection

Lignox 2% A Injection belongs to the class of local anaesthetics known as numbing medication used to produce local numbness (anaesthesia) on skin before surgical procedure and reduce pain and discomfort caused by invasive medical procedures such as surgery. It is also used to reduce the discomfort of contractions during labour. Lignox 2% A Injection is also used to treat certain types of chronic pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person.

Lignox 2% A Injection is a combination of two drugs: Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lidocaine works by blocking the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain. Adrenaline works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine.

Lignox 2% A Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side-effects such as reactions at the application site (burning, itching, redness, and irritation), nausea, vomiting and allergy. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

The usage of Lignox 2% A Injection is not allowed in patients who are hypersensitive to any of the components present in it as it may cause serious side effects.  Before starting the medication, tell your doctor about your medical history, especially if you have high blood pressure or heart problems such as a slow heart beat, hypovolaemia (decreased volume of blood), epilepsy, diabetes, liver disease, a certain blood disorder (methemoglobinemia). Please consult a doctor if you are pregnant or breastfeeding before taking Lignox 2% A Injection. Lignox 2% A Injection is not recommended for children. 

Uses of Lignox 2% A Injection

Pain relief (local anaesthesia).

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Lignox 2% A Injection is a combination of two medicines, namely; Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lignox 2% A Injection is used to produce local numbness (anaesthesia). Lidocaine is a local anesthetic which works by blocking the transmission of the nerve signals in the body, thereby helps in decreasing the sensation of pain. Adrenaline is a vasoconstrictor which works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine. Lignox 2% A Injection is used to reduce pain and discomfort caused by invasive medical procedures such as surgery, needle punctures or insertion of a breathing tube or catheter. It is also used to reduce the discomfort of contractions during labour. Lignox 2% A Injection will start to work rapidly after being injected and will slowly wear off when the surgical procedure is over.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Lignox 2% A Injection if you are pregnant or breastfeeding, your doctor will prescribe you Lignox 2% A Injection only if the benefits outweigh the risks. Lignox 2% A Injection causes drowsiness, so drive with caution. Avoid consuming alcohol along with Lignox 2% A Injection as it could lead to increased drowsiness. Lignox 2% A Injection may not be suitable for people with respiratory disease, heart disease, epilepsy, low blood pressure, kidney or liver problems. Inform your doctor about your health condition and medications before taking Lignox 2% A Injection to rule out any side-effects.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lignox 2% A Injection 30 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with Saquinavir can increase the blood levels of Lignox 2% A Injection 30 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lignox 2% A Injection 30 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Dapsone with Lignox 2% A Injection 30 ml can increase the risk of methemoglobinemia (a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Lignox 2% A Injection 30 ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Lignox 2% A Injection 30 ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with phenobarbital may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking phenobarbital and Lignox 2% A Injection 30 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with Nitrofurantoin may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Nitrofurantoin with Lignox 2% A Injection 30 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocainePrilocaine
Severe
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with Prilocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Lignox 2% A Injection 30 ml with Prilocaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lignox 2% A Injection 30 ml:
Combination of chloroquine and Lignox 2% A Injection 30 ml can increase the risk of methemoglobinemia (an uncommon disease that can result in low oxygen levels in tissues and important organs).

How to manage the interaction:
Taking chloroquine and Lignox 2% A Injection 30 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience any of the following symptoms: gray discoloration of the skin, abnormal blood coloring, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, rapid heartbeat, palpitations, anxiety, or confusion, consult your doctor
LidocaineAmyl nitrite
Severe
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Lignox 2% A Injection 30 ml with Amyl nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Lignox 2% A Injection 30 ml and Amyl nitrite, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineIohexol
Severe
How does the drug interact with Lignox 2% A Injection 30 ml:
Taking Iohexol and Lignox 2% A Injection 30 ml may increase the risk of causing seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Lignox 2% A Injection 30 ml and Iohexol, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​Indulge yourself in mindfulness activities like yoga that help in reducing stress levels and pain management.
  • Never forget to get about 7-8 hours of sleep as it will help your muscles to heal fast and reduces inflammation and swelling.
  • Take out some time for meditation, read books, take a warm bubble bath, spend time with family or listen to relaxing music.
  • Make a habit of eating food rich in antioxidants such as berries, onion, milk, spinach, kidney beans, dark chocolate, etc.
  • Foods rich in flavonoids helps the body to heal faster by reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Strictly limit smoking and alcohol consumption as it may worsen the side effects of the drug.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS

Lignox 2% A Injection Substitute

Substitutes safety advice
  • Biocaine ADR 24.64mg/0.0125mg Injection

    by Others

    0.96per tablet
  • Exocaine Injection 30 ml

    by Others

    0.96per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lignox 2% A Injection contains Lidocaine and Adrenaline. Lidocaine blocks the influx of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses (nerve signal). Hence, it gives an anesthetic effect and decreases the sensation of pain. Adrenaline works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it decreasing the bleeding and the effects of Lignox 2% A Injection will last longer.

You are not recommended to take duloxetine (antidepressant) with Lignox 2% A Injection as co-administration of these two medicines may increase the risk of high blood pressure and heart rate. However, please consult your doctor before taking other medicines with Lignox 2% A Injection.

Lignox 2% A Injection causes drowsiness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

A person of age 65 or older should use Lignox 2% A Injection with caution, as directed by the doctor as the chances of occurrence of side effects increase in older people.

Lignox 2% A Injection should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking Lignox 2% A Injection so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

Drug-Drug Interactions Checker List

  • LORAZEPAM
  • ALPRAZOLAM
  • HALOTHANE
  • PRILOCAINE
  • TRAMADOL
  • AMIODARONE
  • PROPRANOLOL
  • SODIUM NITRITE
  • DOMPERIDONE
  • CIMETIDINE
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Special Advise

Inform your doctor about any blood diseases/problems like hypovolaemia (decreased volume of blood), heart problems such as a slow heart beat, difficulty breathing or ever had a stroke.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

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