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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Admac Lifesciences(Oncology)

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Linamac 10 Capsule 21's

Linamac 10 Capsule 21's belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Linamac 10 Capsule 21's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS where part of chromosome 5 is missing.
 
Linamac 10 Capsule 21's contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Linamac 10 Capsule 21's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Linamac 10 Capsule 21's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Linamac 10 Capsule 21's if you are pregnant or breastfeeding. Linamac 10 Capsule 21's may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Linamac 10 Capsule 21's is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Linamac 10 Capsule 21's must use effective contraception. Inform your doctor regarding your health condition and medications before taking Linamac 10 Capsule 21's to rule out any interactions.

Uses of Linamac 10 Capsule 21's

Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Linamac 10 Capsule 21's as a whole with water; do not crush or chew it.

Medicinal Benefits

Linamac 10 Capsule 21's belongs to the group of medicines called immunomodulatory agents. Linamac 10 Capsule 21's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Linamac 10 Capsule 21's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Linamac 10 Capsule 21's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Linamac 10 Capsule 21's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Linamac 10 Capsule 21's if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Linamac 10 Capsule 21's if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Linamac 10 Capsule 21's if you are breastfeeding as it is not unknown if it passes into breastmilk. Linamac 10 Capsule 21's may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Linamac 10 Capsule 21's is not recommended for use in children. Avoid consuming alcohol along with Linamac 10 Capsule 21's as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
LenalidomideYellow fever vaccine
Critical

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
How does the drug interact with Linamac 10 Capsule:
Administering the Rotavirus vaccine together with Linamac 10 Capsule may increase the risk of infections.

How to manage the interaction:
Taking Linamac 10 Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Linamac 10 Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Linamac 10 Capsule:
When combining the Yellow fever vaccine with Linamac 10 Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Linamac 10 Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Linamac 10 Capsule:
Taking anakinra with Linamac 10 Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Linamac 10 Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Linamac 10 Capsule:
Combining the BCG vaccine with Linamac 10 Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Linamac 10 Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideVedolizumab
Severe
How does the drug interact with Linamac 10 Capsule:
Combining Linamac 10 Capsule with Vedolizumab can increase the chances of experiencing harmful side effects.

How to manage the interaction:
Taking Linamac 10 Capsule with Vedolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms of infection, such as chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop using any medications without first talking to your doctor.
LenalidomideTestosterone
Severe
How does the drug interact with Linamac 10 Capsule:
Coadministration of Linamac 10 Capsule with Testosterone can increase levels of testosterone in the blood.

How to manage the interaction:
Coadministration of Testosterone with Linamac 10 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
LenalidomideAtezolizumab
Severe
How does the drug interact with Linamac 10 Capsule:
Using Atezolizumab and Linamac 10 Capsule can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Atezolizumab and Linamac 10 Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideLeflunomide
Severe
How does the drug interact with Linamac 10 Capsule:
Combining Linamac 10 Capsule with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Linamac 10 Capsule and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
LenalidomidePalifermin
Severe
How does the drug interact with Linamac 10 Capsule:
When Palifermin is used with Linamac 10 Capsule, it might reduce its effectiveness and potentially exacerbate mouth ulcers.

How to manage the interaction:
Although there is a possible interaction between Linamac 10 Capsule and Palifermin, you can take these medicines together if prescribed by your doctor. If you have painful sores or ulcers in your mouth, it's important to contact your doctor right away. It is recommended not to use palifermin within 24 hours before or after treatment with Linamac 10 Capsule. Do not discontinue any medications without consulting your doctor.
LenalidomideDeferiprone
Severe
How does the drug interact with Linamac 10 Capsule:
Taking Linamac 10 Capsule with deferiprone together can cause a decrease in white blood cell count.

How to manage the interaction:
Although there is an interaction between Linamac 10 Capsule and deferiprone, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Linamac 10 Capsule 21's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Linamac 10 Capsule 21's on your own. You are advised to take Linamac 10 Capsule 21's for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Linamac 10 Capsule 21's.

No, it is not safe to father a child while taking Linamac 10 Capsule 21's. Linamac 10 Capsule 21's can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Linamac 10 Capsule 21's and for at least 4weeks after discontinuing Linamac 10 Capsule 21's, even if you have undergone a successful vasectomy. Male patients taking Linamac 10 Capsule 21's must not donate semen whilst taking Linamac 10 Capsule 21's and for 4weeks after discontinuing Linamac 10 Capsule 21's.

Patients taking Linamac 10 Capsule 21's must not donate blood during the treatment with Linamac 10 Capsule 21's and for 1month after discontinuation of Linamac 10 Capsule 21's as the donated blood might be given to pregnant women whose foetus should not be exposed to Linamac 10 Capsule 21's since it causes severe birth defects.

People with multiple myeloma taking Linamac 10 Capsule 21's may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Linamac 10 Capsule 21's for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Linamac 10 Capsule 21's might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Linamac 10 Capsule 21's.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Special Advise

  • Do not take Linamac 10 Capsule 21's if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking Linamac 10 Capsule 21's must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking Linamac 10 Capsule 21's and for 4weeks after discontinuing Linamac 10 Capsule 21's.
  • Linamac 10 Capsule 21's might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.
  • Linamac 10 Capsule 21's might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Linamac 10 Capsule 21's.
  • Linamac 10 Capsule 21's might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Linamac 10 Capsule 21's. Consult your doctor if you are diabetic.
  • Inform your doctor if you have any kidney dysfunction as Linamac 10 Capsule 21's might cause kidney problems.
  • Regular blood tests are advised before and during treatment with Linamac 10 Capsule 21's.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is the cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. Incase of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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