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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lomotil Tablet

Lomotil Tablet belongs to the group of medicines called antidiarrheal used to treat diarrhoea. Diarrhoea is a condition characterized by loose and watery stools with a frequent need to have a bowel movement. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down the intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Atropine is added to prevent the abuse of diphenoxylate as higher doses may cause physical dependence.

You are advised to take Lomotil Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, nausea, vomiting, headache, dry mouth and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.

Uses of Lomotil Tablet

Diarrhoea

Directions for Use

You can take Lomotil Tablet with or without food. Swallow Lomotil Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Lomotil Tablet belongs to the group of medicines called antidiarrheals used to treat diarrhoea. Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Together, Lomotil Tablet helps to treat diarrhoea.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Lomotil Tablet if you are allergic to any of its contents; if you have obstructive jaundice, diarrhoea caused by bacteria or antibiotics. Do not take monoamine oxidase inhibitors (MAOI) with Lomotil Tablet . Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.

Drug-Drug Interactions

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AtropineHydromorphone
Severe

Drug-Drug Interactions

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How does the drug interact with Lomotil Tablet:
When Lomotil Tablet is used with solifenacin may cause side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems).

How to manage the interaction:
Co- administration of Lomotil Tablet with solifenacin can lead to an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, reduced sweating, trouble urinating, abdominal cramps, constipation, irregular heartbeat, disorientation, and memory issues, consult the doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
AtropineHydromorphone
Severe
How does the drug interact with Lomotil Tablet:
Using Hydromorphone together with Lomotil Tablet may increase the risk and/or severity of some side effects (dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation).

How to manage the interaction:
Although taking Hydromorphone and Lomotil Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: trouble peeing, feeling dizzy or sleepy, feeling confused or having trouble focusing, dry mouth, constipation, or feeling less mentally sharp. Do not discontinue any medications without consulting a doctor.
AtropineUmeclidinium bromide
Severe
How does the drug interact with Lomotil Tablet:
Using Lomotil Tablet together with umeclidinium may increase side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes).

How to manage the interaction:
Although taking Lomotil Tablet and Umeclidinium bromide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lomotil Tablet:
Coadministration of Lomotil Tablet and Zonisamide can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Lomotil Tablet and Zonisamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AtropinePramlintide
Severe
How does the drug interact with Lomotil Tablet:
Coadministration of Pramlintide with Lomotil Tablet can increase the risk of reduced movement in the digestive system.

How to manage the interaction:
Taking Lomotil Tablet with Pramlintide together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lomotil Tablet:
When Lomotil Tablet and Topiramate are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Lomotil Tablet and topiramate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lomotil Tablet:
Co-administration of Lomotil Tablet with Potassium chloride oral tablets or capsules can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Lomotil Tablet and Potassium chloride, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact the doctor right away: severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting(especially with blood), decreased hunger, dark, tarry stools. Do not discontinue any medications without a doctor's advice.
AtropineSecretin
Severe
How does the drug interact with Lomotil Tablet:
When Secretin human is used with Lomotil Tablet, the therapeutic efficacy of Secretin human can be decrease.

How to manage the interaction:
Although there is a possible interaction between Lomotil Tablet and Secretin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtropinePotassium citrate
Severe
How does the drug interact with Lomotil Tablet:
Taking potassium citrate oral tablets or capsules with Lomotil Tablet may increase the irritating effects of potassium on stomach and upper intestine.

How to manage the interaction:
Taking Lomotil Tablet with potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtropineTirzepatide
Moderate
How does the drug interact with Lomotil Tablet:
When Lomotil Tablet is taken along with tirzepatide it may increase the heart rate.

How to manage the interaction:
Patients on Lomotil Tablet should take tirzepatide with caution because both medications may elevate heart rate.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include bananas, apple, toast, and rice in your diet to firm the stools.
  • Stay hydrated by drinking plenty of fluids to compensate for electrolyte loss.
  • Clear broths and ORS can help provide essential electrolytes.
  • Avoid spicy, fried and processed foods.
  • Take ample rest.
  • Avoid the intake of foods which can trigger diarrhoea.
  • Do not consume contaminated food or water.
  • It is advised to intake plenty of fluids to compensate for the loss of electrolytes and salts due to diarrhoea.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lomotil Tablet contains Diphenoxylate and Atropine. Diphenoxylate works by slowing down intestinal movements, thereby making the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine.

Dry mouth could be a side-effect of Lomotil Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Constipation might be a side-effect of Lomotil Tablet . Drink enough fluids and eat fibre-rich food if you experience constipation. Consult your doctor if the condition persists or worsens.

Do not take anti-depressants, especially MAO inhibitors, along with Lomotil Tablet as it may cause headache, high blood pressure, and hyperthermia (high temperature). Consult your doctor before taking Lomotil Tablet with other medicines to avoid unpleasant side effects.

Do not take Lomotil Tablet for longer durations unless prescribed. Generally, your condition will get better within 48hours of taking Lomotil Tablet . Talk to your doctor if there is no improvement even after taking Lomotil Tablet for 10 days.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • PREGABALIN
  • DULOXETINE
  • METOPROLOL
  • ACETAMINOPHEN
  • HYDROCODONE

Disease/Condition Glossary

Diarrhoea: It is a condition characterized by loose and watery stools with a frequent need to have a bowel movement. Diarrhoea might be a result of bacterial or viral infection. It can be acute (lasts for a few days) or chronic (lasts for a few weeks). Diarrhoea can lead to loss of water along with salts, electrolytes, and minerals from the body. The common causes of diarrhoea include food intolerance, food allergy, adverse reaction to a medication, or infections. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

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