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About Lomotil Tablet
Lomotil Tablet belongs to the group of medicines called antidiarrheal used to treat diarrhoea. Diarrhoea is a condition characterized by loose and watery stools with a frequent need to have a bowel movement. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.
Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down the intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Atropine is added to prevent the abuse of diphenoxylate as higher doses may cause physical dependence.
You are advised to take Lomotil Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, nausea, vomiting, headache, dry mouth and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.
Uses of Lomotil Tablet

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Key Benefits
Lomotil Tablet belongs to the group of medicines called antidiarrheals used to treat diarrhoea. Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Together, Lomotil Tablet helps to treat diarrhoea.
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Drug Warnings
Do not take Lomotil Tablet if you are allergic to any of its contents; if you have obstructive jaundice, diarrhoea caused by bacteria or antibiotics. Do not take monoamine oxidase inhibitors (MAOI) with Lomotil Tablet . Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.
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Diet & Lifestyle Advise
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Therapeutic Class
Alcohol
Safe if prescribed
Avoid consuming alcohol while taking Lomotil Tablet as it may cause increased dizziness and drowsiness.
Pregnancy
Consult your doctor
Lomotil Tablet belongs to pregnancy category C. Please consult your doctor before taking Lomotil Tablet if you are pregnant; your doctor will prescribe Lomotil Tablet only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Lomotil Tablet may pass into breastmilk. Consult your doctor before taking Lomotil Tablet ; your doctor will decide whether Lomotil Tablet can be taken by breastfeeding mothers or not.
Driving
Safe if prescribed
Lomotil Tablet may cause dizziness and drowsiness. Do not drive or operate machinery if you feel dizzy or drowsy.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor before taking Lomotil Tablet if you have liver impairment/liver disease before taking Lomotil Tablet .
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or kidney impairment/kidney disease before taking Lomotil Tablet .
Children
Safe if prescribed
Lomotil Tablet should not be given to children below 13 years as the safety and effectiveness have not been established.
Lomotil Tablet contains Diphenoxylate and Atropine. Diphenoxylate works by slowing down intestinal movements, thereby making the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine.
Dry mouth could be a side-effect of Lomotil Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might be a side-effect of Lomotil Tablet . Drink enough fluids and eat fibre-rich food if you experience constipation. Consult your doctor if the condition persists or worsens.
Do not take anti-depressants, especially MAO inhibitors, along with Lomotil Tablet as it may cause headache, high blood pressure, and hyperthermia (high temperature). Consult your doctor before taking Lomotil Tablet with other medicines to avoid unpleasant side effects.
Do not take Lomotil Tablet for longer durations unless prescribed. Generally, your condition will get better within 48hours of taking Lomotil Tablet . Talk to your doctor if there is no improvement even after taking Lomotil Tablet for 10 days.
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