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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

GEMFIBROZIL-300MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lopid Capsule

Lopid Capsule belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Hyperlipidaemia or hypertriglyceridemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased bad cholesterol level leads to a high risk of heart attack and stroke in the future, especially for heart disease patients.

Lopid Capsule contains 'Gemfibrozil' which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid Capsule decreases harmful cholesterol like LDL (bad cholesterol), triglycerides (TG), and increases levels of HDL (good cholesterol).

Take Lopid Capsule as prescribed by your doctor. You are advised to take Lopid Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Most of these side effects of Lopid Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. Before starting Lopid Capsule , please inform your doctor if you have any allergy, severe kidney disease, severe liver disease, or gallbladder disease. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye lens that causes decreased vision) and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid Capsule . Immediately contact your doctor if you are pregnant and breastfeeding.

Uses of Lopid Capsule

High cholesterol levels.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lopid Capsule belongs to a group of medication called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Lopid Capsule works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid Capsule decreases harmful cholesterol like LDL (bad cholesterol), triglycerides (TG), and increases levels of HDL (good cholesterol).

Storage

Store in a cool and dry place away from sunlight
Side effects of Lopid Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Drug Warnings

Before taking Lopid Capsule , tell your doctor if you are allergic to any fibrate products. Inform your doctor if you ever had rhabdomyolysis (high risk of muscle breakdown), thyroid disease, history of muscle pain and weakness. If you are above 70 years, then contact your doctor before taking this Lopid Capsule . Before starting Lopid Capsule , please inform your doctor if you have any allergy, severe kidney disease, severe liver disease, and gallbladder disease before starting $ name. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye's lens that causes decreased vision), diabetes, and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid Capsule . Immediately contact your doctor if you are pregnant and breastfeeding. The use of alcohol with Lopid Capsule increases liver damage, so its use should be avoided.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lopid Capsule:
When Repaglinide is taken with Lopid Capsule, the level of Repaglinide in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Repaglinide with Lopid Capsule can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid Capsule:
When Selexipag is taken with Lopid Capsule, the amount of Selexipag in the blood can go up. This can increase the risk or severity of side effects like anemia, muscle and joint pain, or electrolyte imbalance.

How to manage the interaction:
Taking Selexipag with Lopid Capsule can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle and joint pain, diarrhea, sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, flushing, and decreased appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilCerivastatin
Severe
How does the drug interact with Lopid Capsule:
C-administration of Lopid Capsule with Cerivastatin can develop or increase the risk of liver damage or rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Lopid Capsule with Cerivastatin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and contact your doctor right away if you notice any of these signs - liver problems, muscle damage, kidney problems, complications, pain, weakness, fever, dark urine, chills, joint pain, swelling, bruising, rash, itching, loss of appetite, tiredness, feeling sick, or bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid Capsule:
When Lopid Capsule is taken with Atorvastatin, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Co-administration of Atorvastatin along with Lopid Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lopid Capsule:
Co-administration of Lopid Capsule with Fluvastatin can develop or increase the risk of side effects like muscle damage or liver injury.

How to manage the interaction:
There may be a possibility of interaction between Fluvastatin and Lopid Capsule, but it can be taken if prescribed by a doctor. If you notice any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GemfibrozilPravastatin
Severe
How does the drug interact with Lopid Capsule:
Taking Lopid Capsule with Pravastatin can increase the risk or severity of muscle damage or liver damage.

How to manage the interaction:
Although taking Pravastatin and Lopid Capsule together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilBexarotene
Severe
How does the drug interact with Lopid Capsule:
When Bexarotene is taken with Lopid Capsule, it can cause a decrease in the metabolism of Bexarotene. This can reduce the levels and treatment outcomes of Bexarotene.

How to manage the interaction:
Although there is a possible interaction between Lopid Capsule and Bexarotene, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lopid Capsule:
When taken in combination Lopid Capsule may significantly raise the Loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Loperamide with Lopid Capsule together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lopid Capsule:
Co-administration of Lopid Capsule and Rosuvastatin may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Lopid Capsule and Rosuvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
GemfibrozilEluxadoline
Severe
How does the drug interact with Lopid Capsule:
When Eluxadoline is taken with Lopid Capsule, the amount of Eluxadoline in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Lopid Capsule and Eluxadoline together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - feeling sleepy, feeling sick, throwing up, having trouble going to the bathroom, having a stomachache, or feeling very tired, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Lopid Capsule is generally given in addition to regular exercise and a low-fat diet to lower fat levels in the blood.
  • A low cholesterol diet and a regular exercise regime are found to complement treatment with Lopid Capsule effectively.
  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.
  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.
  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it is beneficial to eat them regularly.
  • Regular exercise can make your heart strong and decrease your risk of a heart attack.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, you may use Lopid Capsule with niacin if recommended by your doctor because Lopid Capsule along with niacin can be used in patients with very high fat.

Follow the diet suggested by your doctor. Lopid Capsule will not help lower your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It may disturb your treatment.

Usually, it is not safe to take Lopid Capsule with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Lopid Capsule along with fusidic acid.

You should not take Lopid Capsule if you have gallbladder disease, severe liver or kidney disease. If you are also taking repaglinide or simvastatin, then you should not take Lopid Capsule .

Lopid Capsule is used with caution in patients taking warfarin, adjustments in warfarin may be required, consult your doctor before taking Lopid Capsule along with warfarin.

Drug-Drug Interactions Checker List

  • ROSIGLITAZONE
  • PIOGLITAZONE
  • REPAGLINIDE
  • ATORVASTATIN
  • PRAVASTATIN
  • ROSUVASTATIN
  • LOPERAMIDE
  • MONTELUKAST
  • WARFARIN
  • ACENOCOUMAROL
  • PHENPROCOUMON
  • COLCHICINE
  • DASABVIR
  • LOVASTATIN
  • DABRAFENIB

Special Advise

  • You should have your lipid profile test including total cholesterol (TC), triglycerides (TG), LDL, HDL, VLDL every 6 months to ensure whether Lopid Capsule is working or not.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. 
  • Gemfibrozil may cause you to develop gallstones. If you develop gallstones, you should consult your doctor.

Disease/Condition Glossary

Hyperlipidemia occurs when there are too many lipids (or fats), like cholesterol and triglycerides (TG). Hypercholesterolemia is a type of Hyperlipidemia in which there is excessive low-density lipoprotein - LDL (bad cholesterol) and low level of high-density lipoprotein - HDL (good cholesterol) in your blood. This condition increases the deposition of fats on the lining of heart arteries, increasing the risk of heart blockage and other blood clot problems. 

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