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Drug-Drug Interactions
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Lori Injection 2 ml:
Co-administration of Tapentadol together with Lori Injection 2 ml can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.
How to manage the interaction:
Taking Lori Injection 2 ml with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
Co-administration of Tapentadol together with Lori Injection 2 ml can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.
How to manage the interaction:
Taking Lori Injection 2 ml with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lori Injection 2 ml:
Co-administration of Lori Injection 2 ml with clozapine may increase the effects of both medicines.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml can be taken with clozapine if prescribed by the doctor. Consult the prescriber if you experience side effects like low blood pressure, confusion, drowsiness, shallow breathing, incoordination, and weak pulse. Your doctor may advise dose adjustment or frequent monitoring to safely use both medicines. Do not discontinue the medications without consulting a doctor.
Co-administration of Lori Injection 2 ml with clozapine may increase the effects of both medicines.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml can be taken with clozapine if prescribed by the doctor. Consult the prescriber if you experience side effects like low blood pressure, confusion, drowsiness, shallow breathing, incoordination, and weak pulse. Your doctor may advise dose adjustment or frequent monitoring to safely use both medicines. Do not discontinue the medications without consulting a doctor.
DiazepamCodeine
Severe
How does the drug interact with Lori Injection 2 ml:
Co-administration of Lori Injection 2 ml with codeine may cause serious side effects.
How to manage the interaction:
Consult your doctor if you are using Lori Injection 2 ml and codeine. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Co-administration of Lori Injection 2 ml with codeine may cause serious side effects.
How to manage the interaction:
Consult your doctor if you are using Lori Injection 2 ml and codeine. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Lori Injection 2 ml:
Co-administration of Lori Injection 2 ml with tramadol may cause serious side effects like respiratory distress or coma.
How to manage the interaction:
Consult the doctor if you are taking Lori Injection 2 ml and tramadol. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Co-administration of Lori Injection 2 ml with tramadol may cause serious side effects like respiratory distress or coma.
How to manage the interaction:
Consult the doctor if you are taking Lori Injection 2 ml and tramadol. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
DiazepamRemifentanil
Severe
How does the drug interact with Lori Injection 2 ml:
Co-administration of Remifentanil with Lori Injection 2 ml can increase the seriousness of side effects.
How to manage the interaction:
Although taking Lori Injection 2 ml and Remifentanil together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your health and talk to your doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of Remifentanil with Lori Injection 2 ml can increase the seriousness of side effects.
How to manage the interaction:
Although taking Lori Injection 2 ml and Remifentanil together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your health and talk to your doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
DiazepamHydromorphone
Severe
How does the drug interact with Lori Injection 2 ml:
Taking of Lori Injection 2 ml with hydromorphone may cause serious side effects like respiratory depression.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml should be taken with hydromorphone only if prescribed by the doctor. Consult the doctor if you have any concerns, doctor may prescribe alternatives that do not interact. Do not discontinue the medication without consulting a doctor.
Taking of Lori Injection 2 ml with hydromorphone may cause serious side effects like respiratory depression.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml should be taken with hydromorphone only if prescribed by the doctor. Consult the doctor if you have any concerns, doctor may prescribe alternatives that do not interact. Do not discontinue the medication without consulting a doctor.
DiazepamSufentanil
Severe
How does the drug interact with Lori Injection 2 ml:
Co-administration of Sufentanil with Lori Injection 2 ml can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Lori Injection 2 ml with Sufentanil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
Co-administration of Sufentanil with Lori Injection 2 ml can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Lori Injection 2 ml with Sufentanil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamEsketamine
Severe
How does the drug interact with Lori Injection 2 ml:
Co-administration of Lori Injection 2 ml with esketamine may increase side effects such as confusion, drowsiness, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml should be taken with esketamine if prescribed by the doctor. However, avoid driving or operating heavy machinery after treatment with esketamine as you may experience drowsiness. Do not discontinue the medication without consulting a doctor.
Co-administration of Lori Injection 2 ml with esketamine may increase side effects such as confusion, drowsiness, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml should be taken with esketamine if prescribed by the doctor. However, avoid driving or operating heavy machinery after treatment with esketamine as you may experience drowsiness. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Lori Injection 2 ml:
Taking Lori Injection 2 ml together with fluvoxamine may cause an increase in side effects such as drowsiness, confusion, muscle weakness, and fainting.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml can be taken with fluvoxamine if prescribed by the doctor. However, if you experience any unusual symptoms consult your doctor. Do not discontinue any medications without consulting a doctor.
Taking Lori Injection 2 ml together with fluvoxamine may cause an increase in side effects such as drowsiness, confusion, muscle weakness, and fainting.
How to manage the interaction:
Although there is a possible interaction, Lori Injection 2 ml can be taken with fluvoxamine if prescribed by the doctor. However, if you experience any unusual symptoms consult your doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Lori Injection 2 ml:
Taking Lori Injection 2 ml together with olanzapine can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.
How to manage the interaction:
Combining Olanzapine and Lori Injection 2 ml can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
Taking Lori Injection 2 ml together with olanzapine can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.
How to manage the interaction:
Combining Olanzapine and Lori Injection 2 ml can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Lori Injection 2 ml Substitute
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Drug-Diseases Interactions
DIAZEPAM-5MGMyasthenia gravis and other myoneural disorders
Severe
DIAZEPAM-5MGEssential (primary) hypertension
Severe
Drug-Diseases Interactions
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DIAZEPAM-5MGMyasthenia gravis and other myoneural disorders
Severe
How does the disease interact with Lori Injection 2 ml:
Lori Injection 2 ml shouldn't be used by people with myasthenia gravis.
How to manage the interaction:
The use of Lori Injection 2 ml is not recommended in patients with myasthenia gravis (an autoimmune disease).
Lori Injection 2 ml shouldn't be used by people with myasthenia gravis.
How to manage the interaction:
The use of Lori Injection 2 ml is not recommended in patients with myasthenia gravis (an autoimmune disease).
DIAZEPAM-5MGEssential (primary) hypertension
Severe
How does the disease interact with Lori Injection 2 ml:
Injecting benzodiazepines into individuals who are in shock or a coma is not advised. In these patients, the hypnotic and hypotensive effects of these drugs may last longer and be more potent.
How to manage the interaction:
The hypnotic (sleep-inducing) and hypotensive (lowering blood pressure) effects of these agents may be prolonged and intensified. The medicine should not be administered to patients in shock or coma.
Injecting benzodiazepines into individuals who are in shock or a coma is not advised. In these patients, the hypnotic and hypotensive effects of these drugs may last longer and be more potent.
How to manage the interaction:
The hypnotic (sleep-inducing) and hypotensive (lowering blood pressure) effects of these agents may be prolonged and intensified. The medicine should not be administered to patients in shock or coma.
DIAZEPAM-5MGEpilepsy
Severe
How does the disease interact with Lori Injection 2 ml:
The incidence of generalised tonic-clonic seizures (grand mal) or their onset may be accelerated in people with seizure disorders who use benzodiazepines.
How to manage the interaction:
Benzodiazepines may increase the occurrence of seizures. Dose adjustment or initiation of appropriate anticonvulsant medication may be needed. Do not discontinue medication without first consulting with the physician.
The incidence of generalised tonic-clonic seizures (grand mal) or their onset may be accelerated in people with seizure disorders who use benzodiazepines.
How to manage the interaction:
Benzodiazepines may increase the occurrence of seizures. Dose adjustment or initiation of appropriate anticonvulsant medication may be needed. Do not discontinue medication without first consulting with the physician.
DIAZEPAM-5MGAbnormalities of breathing
Severe
How does the disease interact with Lori Injection 2 ml:
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea.
How to manage the interaction:
Usually when given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in these patients.
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea.
How to manage the interaction:
Usually when given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in these patients.
DIAZEPAM-5MGOther diseases of liver
Severe
How does the disease interact with Lori Injection 2 ml:
The liver breaks down benzodiazepines, and the metabolites are then eliminated in the urine. The oxidative N-dealkylation of chlordiazepoxide, clorazepate, Lori Injection 2 ml, flurazepam, and quazepam results in active metabolites that have significantly longer half-lives than the parent substance.
How to manage the interaction:
Benzodiazepines are metabolized by the liver. Therapy with benzodiazepines should be administered cautiously at lower initial dosages in patients with impaired liver function.
The liver breaks down benzodiazepines, and the metabolites are then eliminated in the urine. The oxidative N-dealkylation of chlordiazepoxide, clorazepate, Lori Injection 2 ml, flurazepam, and quazepam results in active metabolites that have significantly longer half-lives than the parent substance.
How to manage the interaction:
Benzodiazepines are metabolized by the liver. Therapy with benzodiazepines should be administered cautiously at lower initial dosages in patients with impaired liver function.
DIAZEPAM-5MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe
How does the disease interact with Lori Injection 2 ml:
It is possible for benzodiazepines to lead to abuse and dependence. Particularly with repeated usage and/or high dosages, tolerance and physical and psychological dependence may develop.
How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. It should be used with caution in patients with addiction- prone individuals, such as those with a history of alcohol or substance abuse. The dose should be gradually reduced if dependency is suspected.
It is possible for benzodiazepines to lead to abuse and dependence. Particularly with repeated usage and/or high dosages, tolerance and physical and psychological dependence may develop.
How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. It should be used with caution in patients with addiction- prone individuals, such as those with a history of alcohol or substance abuse. The dose should be gradually reduced if dependency is suspected.
DIAZEPAM-5MGGlaucoma
Severe
How does the disease interact with Lori Injection 2 ml:
The makers believe that using benzodiazepines while a patient has acute angle-closure glaucoma or untreated open-angle glaucoma is contraindicated.
How to manage the interaction:
Benzodiazepine is not recommended in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
The makers believe that using benzodiazepines while a patient has acute angle-closure glaucoma or untreated open-angle glaucoma is contraindicated.
How to manage the interaction:
Benzodiazepine is not recommended in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
DIAZEPAM-5MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Lori Injection 2 ml:
Alcohol and benzodiazepines should not be combined. Vital signs are decreased in alcohol-intoxicated patients.
How to manage the interaction:
The use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.
Alcohol and benzodiazepines should not be combined. Vital signs are decreased in alcohol-intoxicated patients.
How to manage the interaction:
The use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.
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