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About Losawell C 50mg/12.5mg Tablet

Losawell C 50mg/12.5mg Tablet belongs to the class of ‘anti-hypertensive drugs’ primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases like heart attack, stroke, myocardial infarction etc. 

Losawell C 50mg/12.5mg Tablet consists of two medicines, namely: Losartan and Chlorthalidone. Losartan belongs to a group of angiotensin II receptor antagonists which narrows constricted blood vessels and widens it. Thus, it lowers elevated blood pressure and increases blood flow by preventing blood vessel narrowing. Chlorthalidone belongs to thiazide diuretics (water pill) which inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Thus, it also relaxes the blood vessels to improve blood circulation and lowers raised blood pressure.  

Your doctor will decide the dosage of Losawell C 50mg/12.5mg Tablet based on your medical condition. In some cases, Losawell C 50mg/12.5mg Tablet can cause side effects like nausea, taste changes, stomach upset, diarrhoea, headache, weakness, dizziness and decreased blood pressure. Most of these side effects of Losawell C 50mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Losawell C 50mg/12.5mg Tablet or any other medicines, please inform your doctor. Before taking Losawell C 50mg/12.5mg Tablet, let your doctor know if you have any kidney, liver problems or severe dehydration. Pregnant and breastfeeding women should consult their doctor before taking Losawell C 50mg/12.5mg Tablet. Please do not stop taking Losawell C 50mg/12.5mg Tablet on your own, leading to the recurrence of symptoms or worsening the condition. Do not consume alcohol with Losawell C 50mg/12.5mg Tablet as it may increase the risk of low blood pressure. Avoid driving or operating machinery if you experience dizziness.

Uses of Losawell C 50mg/12.5mg Tablet

High blood pressure (hypertension)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Losawell C 50mg/12.5mg Tablet is an anti-hypertensive medication that treats high blood pressure (hypertension). It consists of Losartan and Chlorthalidone. Losartan is an angiotensin II receptor antagonist. It lowers the blood pressure and increases the blood flow by inhibiting angiotensin (a hormone that constricts blood vessels). Losartan is also used to treat stroke and slow down kidney damage in people with type 2 diabetes. It also increases urinary flow rate and aids in the excretion of electrolytes like chloride, magnesium, calcium and phosphate and by-products like uric acid. Chlorthalidone is a thiazide diuretic (water pill) with antihypertensive activity. It inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Chlorthalidone lowers blood pressure by decreasing the amount of blood the heart pumps (cardiac output) and reducing plasma and extracellular fluid volume (body fluids outside the cells). 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Let your doctor know if you have any history of heart, kidney or liver diseases, severe dehydration, high potassium levels (hyperkalaemia), low potassium levels (hypokalaemia), diabetes, high cholesterol levels, electrolyte imbalance, asthma, lupus (an autoimmune disease), gout and thyroid disorders before starting Losawell C 50mg/12.5mg Tablet. Pregnant women should consult their doctor before taking Losawell C 50mg/12.5mg Tablet. Chlorthalidone in Losawell C 50mg/12.5mg Tablet passes into the breast milk during breastfeeding. Hence, it is advised to inform your doctor before using Losawell C 50mg/12.5mg Tablet if you are a nursing mother. Avoid operating any machines or doing any work that needs mental alertness if you feel dizzy after taking Losawell C 50mg/12.5mg Tablet. It is advised to avoid alcohol consumption while using Losawell C 50mg/12.5mg Tablet to prevent dizziness and risk of low blood pressure. Losawell C 50mg/12.5mg Tablet is not recommended for use in patients younger than 18 years of age. 

Drug-Drug Interactions

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LosartanCaptopril
Severe

Drug-Drug Interactions

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How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Co-administration of Losawell C 50mg/12.5mg Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
LosartanCaptopril
Severe
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanPotassium citrate
Severe
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Co-administration of Losawell C 50mg/12.5mg Tablet with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Benazepril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Benazepril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Using enalapril together with Losawell C 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enalapril with Losawell C 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losawell C 50mg/12.5mg Tablet:
Coadministration of Losawell C 50mg/12.5mg Tablet with Lisinopril can increase potassium levels.

How to manage the interaction:
Taking Losawell C 50mg/12.5mg Tablet with Lisinopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart diseases. 
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Losawell C 50mg/12.5mg Tablet Substitute

Substitutes safety advice
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  • BILOSAR 12.5MG TABLET

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Losawell C 50mg/12.5mg Tablet works by relaxing and widening the blood vessels to make the heart pump blood easily throughout the body and also prevents fluid retention due to excess salts build-up, thereby lowering the raised blood pressure.

Losawell C 50mg/12.5mg Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.

Losawell C 50mg/12.5mg Tablet can cause high levels of potassium in the blood leading to hyperkalaemia. Hence it is not recommended to use potassium supplements along with Losawell C 50mg/12.5mg Tablet. However, consult your doctor if you are already taking other medicines before starting Losawell C 50mg/12.5mg Tablet.

Chlorthalidone in Losawell C 50mg/12.5mg Tablet may affect blood sugar levels in people with diabetes. Hence, it is advised to monitor your sugar levels while taking Losawell C 50mg/12.5mg Tablet regularly. Your doctor may adjust the dose accordingly. Please seek medical advice for more information before starting Losawell C 50mg/12.5mg Tablet.

Even though your blood pressure becomes normal after using Losawell C 50mg/12.5mg Tablet, it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Losawell C 50mg/12.5mg Tablet can cause dehydration. It is advised to drink plenty of fluids and avoid hard exercises and sports to prevent dehydration. If you experience extreme thirst and dry mouth for a longer period, please seek medical advice.

Drug-Drug Interactions Checker List

  • LISINOPRIL
  • BENAZEPRIL
  • ALISKIREN
  • IBUPROFEN
  • NAPROXEN
  • DOFETILIDE
  • DROSPIRENONE
  • CISAPRIDE
  • LITHIUM

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. Low salt/sodium diet and regular exercise are recommended along with Losawell C 50mg/12.5mg Tablet for effective results.
  • Thiazide diuretics like Chlorthalidone may increase serum triglyceride and cholesterol levels. Hence it is advised to monitor your cholesterol levels regularly.
  • Chlorthalidone in Losawell C 50mg/12.5mg Tablet may interfere with specific lab tests like parathyroid test and protein-bound iodide test, hence mention that you are using Losawell C 50mg/12.5mg Tablet in advance to the laboratory staff.
  • Your doctor may advise you to get a regular kidney function test, blood examinations for potassium levels and other electrolytes while using Losawell C 50mg/12.5mg Tablet to rule out any renal impairment.
  • Regular monitoring of blood glucose levels is advised in diabetic patients while using Losawell C 50mg/12.5mg Tablet.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. Blood pressure is defined as the amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow. If the heart pumps more blood, then arteries become narrower, and in turn, blood pressure becomes high. If blood pressure becomes uncontrolled, it may lead to serious heart diseases, including stroke and heart attack. Additionally, high blood pressure can also cause brain damage (stroke), and kidney failure. Blood pressure is expressed as systolic and diastolic pressures. Systolic blood pressure represents the contraction and relaxation of the heart. Diastolic pressure is exerted in the blood vessels when the heart beats and is in the resting state. Ideal blood pressure should be between 90/60mmHg and 120/80mmHg. Hypertension is detected when systolic blood pressure is more than 140mmHg, and diastolic pressure is higher than 90mmHg. Some of the symptoms of hypertension include headache, nose bleed, vomiting, and chest pain. 

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