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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Lox 2% Adrenaline Injection

Lox 2% Adrenaline Injection belongs to the class of local anaesthetics known as numbing medication used to produce local numbness (anaesthesia) on skin before surgical procedure and reduce pain and discomfort caused by invasive medical procedures such as surgery. It is also used to reduce the discomfort of contractions during labour. Lox 2% Adrenaline Injection is also used to treat certain types of chronic pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person.

Lox 2% Adrenaline Injection is a combination of two drugs: Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lidocaine works by blocking the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain. Adrenaline works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine.

Lox 2% Adrenaline Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side-effects such as reactions at the application site (burning, itching, redness, and irritation), nausea, vomiting and allergy. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

The usage of Lox 2% Adrenaline Injection is not allowed in patients who are hypersensitive to any of the components present in it as it may cause serious side effects.  Before starting the medication, tell your doctor about your medical history, especially if you have high blood pressure or heart problems such as a slow heart beat, hypovolaemia (decreased volume of blood), epilepsy, diabetes, liver disease, a certain blood disorder (methemoglobinemia). Please consult a doctor if you are pregnant or breastfeeding before taking Lox 2% Adrenaline Injection. Lox 2% Adrenaline Injection is not recommended for children. 

Uses of Lox 2% Adrenaline Injection

Pain relief (local anaesthesia).

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Lox 2% Adrenaline Injection is a combination of two medicines, namely; Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lox 2% Adrenaline Injection is used to produce local numbness (anaesthesia). Lidocaine is a local anesthetic which works by blocking the transmission of the nerve signals in the body, thereby helps in decreasing the sensation of pain. Adrenaline is a vasoconstrictor which works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine. Lox 2% Adrenaline Injection is used to reduce pain and discomfort caused by invasive medical procedures such as surgery, needle punctures or insertion of a breathing tube or catheter. It is also used to reduce the discomfort of contractions during labour. Lox 2% Adrenaline Injection will start to work rapidly after being injected and will slowly wear off when the surgical procedure is over.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Lox 2% Adrenaline Injection if you are pregnant or breastfeeding, your doctor will prescribe you Lox 2% Adrenaline Injection only if the benefits outweigh the risks. Lox 2% Adrenaline Injection causes drowsiness, so drive with caution. Avoid consuming alcohol along with Lox 2% Adrenaline Injection as it could lead to increased drowsiness. Lox 2% Adrenaline Injection may not be suitable for people with respiratory disease, heart disease, epilepsy, low blood pressure, kidney or liver problems. Inform your doctor about your health condition and medications before taking Lox 2% Adrenaline Injection to rule out any side-effects.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lox 2% Adrenaline Injection 30 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml with Saquinavir can increase the blood levels of Lox 2% Adrenaline Injection 30 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lox 2% Adrenaline Injection 30 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Linezolid with Lox 2% Adrenaline Injection 30 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Linezolid with Lox 2% Adrenaline Injection 30 ml is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Coadministration of Lox 2% Adrenaline Injection 30 ml with Tranylcypromine can increase the risk or severity of high blood pressure or increased heart rate.

How to manage the interaction:
Taking Lox 2% Adrenaline Injection 30 ml with Tranylcypromine is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineDihydroergotamine
Critical
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
When Dihydroergotamine is taken with Lox 2% Adrenaline Injection 30 ml, the amount of Dihydroergotamine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dihydroergotamine with Lox 2% Adrenaline Injection 30 ml is not recommended as it can lead to an interaction. It should be taken only if your doctor has advised it. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, or slurred speech contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Dapsone with Lox 2% Adrenaline Injection 30 ml can increase the risk of methemoglobinemia (a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Lox 2% Adrenaline Injection 30 ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Lox 2% Adrenaline Injection 30 ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml with phenobarbital may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking phenobarbital and Lox 2% Adrenaline Injection 30 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml with Nitrofurantoin may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Nitrofurantoin with Lox 2% Adrenaline Injection 30 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocainePrilocaine
Severe
How does the drug interact with Lox 2% Adrenaline Injection 30 ml:
Taking Lox 2% Adrenaline Injection 30 ml with Prilocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Lox 2% Adrenaline Injection 30 ml with Prilocaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​Indulge yourself in mindfulness activities like yoga that help in reducing stress levels and pain management.
  • Never forget to get about 7-8 hours of sleep as it will help your muscles to heal fast and reduces inflammation and swelling.
  • Take out some time for meditation, read books, take a warm bubble bath, spend time with family or listen to relaxing music.
  • Make a habit of eating food rich in antioxidants such as berries, onion, milk, spinach, kidney beans, dark chocolate, etc.
  • Foods rich in flavonoids helps the body to heal faster by reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Strictly limit smoking and alcohol consumption as it may worsen the side effects of the drug.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lox 2% Adrenaline Injection contains Lidocaine and Adrenaline. Lidocaine blocks the influx of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses (nerve signal). Hence, it gives an anesthetic effect and decreases the sensation of pain. Adrenaline works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it decreasing the bleeding and the effects of Lox 2% Adrenaline Injection will last longer.

You are not recommended to take duloxetine (antidepressant) with Lox 2% Adrenaline Injection as co-administration of these two medicines may increase the risk of high blood pressure and heart rate. However, please consult your doctor before taking other medicines with Lox 2% Adrenaline Injection.

Lox 2% Adrenaline Injection causes drowsiness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

A person of age 65 or older should use Lox 2% Adrenaline Injection with caution, as directed by the doctor as the chances of occurrence of side effects increase in older people.

Lox 2% Adrenaline Injection should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking Lox 2% Adrenaline Injection so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

Drug-Drug Interactions Checker List

  • LORAZEPAM
  • ALPRAZOLAM
  • HALOTHANE
  • PRILOCAINE
  • TRAMADOL
  • AMIODARONE
  • PROPRANOLOL
  • SODIUM NITRITE
  • DOMPERIDONE
  • CIMETIDINE
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Special Advise

Inform your doctor about any blood diseases/problems like hypovolaemia (decreased volume of blood), heart problems such as a slow heart beat, difficulty breathing or ever had a stroke.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

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