Lupibrin Eye Drops 5 ml belongs to a class of anti-glaucoma agents called carbonic anhydrase inhibitors primarily used to treat increased pressure in eye conditions. Glaucoma is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Lupibrin Eye Drops 5 ml contains Brinzolamide which works by inhibiting the action of carbonic anhydrase enzyme and decreasing bicarbonate production essential for the production of fluid in the eye (aqueous humour).  Thus it reduces the secretion of eye fluid called 'aqueous humour' that maintains pressure in the eyeball and in turn lowers the raised pressure in the eye by reducing aqueous humour entry into the eyeball. Thus, Lupibrin Eye Drops 5 ml prevents eyes from getting blind in the conditions of open-angle type glaucoma and ocular hypertension. 

Use Lupibrin Eye Drops 5 ml as prescribed. Lupibrin Eye Drops 5 ml is only for use in the eyes. Do not swallow or inject Lupibrin Eye Drops 5 ml. Your doctor will advise you on how many drops to instil based on your medical condition. In some cases, you may experience eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Most of these side effects of Lupibrin Eye Drops 5 ml do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Lupibrin Eye Drops 5 ml or any other medicines, please tell your doctor. Lupibrin Eye Drops 5 ml is not recommended for children below 18 years of age. You are not advised to use Lupibrin Eye Drops 5 ml if you are pregnant, breastfeeding or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Lupibrin Eye Drops 5 ml as it may cause discolouration of the soft contact lens. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 5 minutes time gap between using Lupibrin Eye Drops 5 ml and other eye drops. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Lupibrin Eye Drops 5 ml.

Lupibrin Eye Drops 5 ml contains Brinzolamide used to treat increased pressure in the eye in conditions such as glaucoma (damage of optic nerve) and ocular hypertension (high fluid pressure inside the eye). Lupibrin Eye Drops 5 ml inhibits the action of carbonic anhydrase enzyme and decreases bicarbonate production that is essential for the production of aqueous humour.  Thereby, it reduces the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) and lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.

• Eye discharge
• Redness, itching, irritation or pain in the eyes
• Blurred vision
• Abnormal eye sensation
• Dry eyes

If you are allergic to Lupibrin Eye Drops 5 ml or any other medicines, please tell your doctor. Lupibrin Eye Drops 5 ml is not recommended for children below 18 years of age. You are not advised to use Lupibrin Eye Drops 5 ml if you are pregnant, breastfeeding, or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Lupibrin Eye Drops 5 ml as it may cause discoloration of the soft contact lens. If you get any new eye problem, an eye infection, or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 5 minutes time gap between using Lupibrin Eye Drops 5 ml and other eye drops. Please do not touch the container tip to the eye, eyelids, or surrounding areas as it may contaminate Lupibrin Eye Drops 5 ml and cause eye infections. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma, or pigmentary glaucoma kidney or liver problems, before taking Lupibrin Eye Drops 5 ml.

Drug-Drug Interaction: Lupibrin Eye Drops 5 ml may have interaction with medicines used to treat glaucoma (dorzolamide, acetazolamide).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Lupibrin Eye Drops 5 ml.

• DORZOLAMIDE
• ACETAZOLAMIDE

• Avoid baked foods such as cakes, cookies, donuts, or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.
• Please cut down your coffee intake as it may increase pressure in the eye and replace coffee with green tea.
• Avoid exercises such as any position where the head is lower than the body like inverted yoga poses as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

• You are recommended to avoid wearing contact lenses while using Lupibrin Eye Drops 5 ml as it may cause discoloration of soft contact lenses.
• Do not use Lupibrin Eye Drops 5 ml if you have used any steroid eye injection within six months, undergone any other intraocular surgery (like cataract surgery) within 6 months, or have had any laser surgery within 12 months.

Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms of glaucoma initially except the slow loss of vision gradually. However, some symptoms include visible rainbow-colored circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance, or nausea.

Ocular hypertension: It is a condition caused due to poor drainage of aqueous humor (fluid in the eye that maintains normal pressure by its continuous flow). This leads to the build-up of excess fluid in the eye resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.