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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

About LUPIGEST 100MG TABLET

LUPIGEST 100MG TABLET belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, LUPIGEST 100MG TABLET also treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

LUPIGEST 100MG TABLET contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take LUPIGEST 100MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of LUPIGEST 100MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, LUPIGEST 100MG TABLET or any other medicines, please tell your doctor. Avoid taking LUPIGEST 100MG TABLET if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking LUPIGEST 100MG TABLET if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking LUPIGEST 100MG TABLET to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking LUPIGEST 100MG TABLET. Drive only if you are alert as LUPIGEST 100MG TABLET may cause drowsiness or dizziness.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of LUPIGEST 100MG TABLET

Female infertility, Female hormonal imbalance

Medicinal Benefits

LUPIGEST 100MG TABLET contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, LUPIGEST 100MG TABLET is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). LUPIGEST 100MG TABLET replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour.

Side Effects of LUPIGEST 100MG TABLET

  • Dizziness
  • Drowsiness
  • Headache
  • Mood changes
  • Diarrhoea
  • Vaginal discharge
  • Joint pain
  • Hot flashes (sudden feeling of warmth) 
  • Constipation

Directions for Use

Take LUPIGEST 100MG TABLET as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take LUPIGEST 100MG TABLET at bedtime as it may cause dizziness or drowsiness.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to soya, LUPIGEST 100MG TABLET or any other medicines, please tell your doctor. Avoid taking LUPIGEST 100MG TABLET if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking LUPIGEST 100MG TABLET if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking LUPIGEST 100MG TABLET to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking LUPIGEST 100MG TABLET. Drive only if you are alert as LUPIGEST 100MG TABLET may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking LUPIGEST 100MG TABLET. If you are about to undergo any surgery, please inform your doctor that you are taking LUPIGEST 100MG TABLET.

Therapeutic Class

HORMONES

Drug-Drug Interactions

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ProgesteroneMorphine
Severe
ProgesteroneVenetoclax
Severe

Drug-Drug Interactions

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ProgesteroneMorphine
Severe
How does the drug interact with LUPIGEST 100MG TABLET:
Co-administration of LUPIGEST 100MG TABLET with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with LUPIGEST 100MG TABLET can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneVenetoclax
Severe
How does the drug interact with LUPIGEST 100MG TABLET:
Co-administration of LUPIGEST 100MG TABLET with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking LUPIGEST 100MG TABLET and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneVenetoclax
Severe
How does the drug interact with LUPIGEST 100MG TABLET:
Co-administration of LUPIGEST 100MG TABLET with Venetoclax may greatly increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking LUPIGEST 100MG TABLET and venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience any symptoms such as nausea, vomiting, diarrhea, fatigue, or bleeding problems, and infections. Do not discontinue any medications without a doctor's advice.
ProgesteroneEdoxaban
Severe
How does the drug interact with LUPIGEST 100MG TABLET:
When LUPIGEST 100MG TABLET is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking LUPIGEST 100MG TABLET and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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PROGESTERONE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PROGESTERONE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grape fruit and its products may interact with LUPIGEST 100MG TABLET Avoid Grape fruit and its products during treatment with LUPIGEST 100MG TABLET

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • RITONAVIR
  • NEVIRAPINE
  • NELFINAVIR
  • EFAVIRENZ
  • DIAZEPAM
  • SPIRONOLACTONE
  • CICLOSPORIN
  • PHENINDIONE
  • TIZANIDINE
  • TERBINAFINE
  • KETOCONAZOLE
  • GRISEOFULVIN

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Special Advise

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Author Details

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Disease/Condition Glossary

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

LUPIGEST 100MG TABLET Substitute

Substitutes safety advice
  • Susten 100 Capsule 10's

    18.63per tablet
  • Naturogest 100 mg Injection 1 ml

    165.60per tablet
  • C-Hop-100 Injection 1 ml

    158.00per tablet
  • STRONE 100MG CAPSULE

    18.81per tablet
  • Endogest 100 mg Tablet 10's

    18.09per tablet
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