Lupihist DM Plus Syrup 60 ml belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear the airways. 

Lupihist DM Plus Syrup 60 ml is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine hydrochloride (decongestant), and Dextromethorphan hydrobromide (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, it helps to provide relief from cough.

Take Lupihist DM Plus Syrup 60 ml as prescribed. Your doctor will recommend how often you need to take Lupihist DM Plus Syrup 60 ml based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Lupihist DM Plus Syrup 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupihist DM Plus Syrup 60 ml. Lupihist DM Plus Syrup 60 ml is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Lupihist DM Plus Syrup 60 ml. Avoid using Lupihist DM Plus Syrup 60 ml if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, or phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupihist DM Plus Syrup 60 ml. 

Lupihist DM Plus Syrup 60 ml contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine hydrochloride is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Lupihist DM Plus Syrup 60 ml helps to relieve cough, cold and allergic symptoms.

• Dry mouth, throat or nose
• Drowsiness
• Dizziness
• Blurred vision
• Headache
• Constipation
• Restlessness or excitation
• Loss of appetite

If you are allergic to Lupihist DM Plus Syrup 60 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupihist DM Plus Syrup 60 ml. Lupihist DM Plus Syrup 60 ml is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Lupihist DM Plus Syrup 60 ml. Avoid taking Lupihist DM Plus Syrup 60 ml if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupihist DM Plus Syrup 60 ml.

Drug-Drug Interaction: Lupihist DM Plus Syrup 60 ml may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killers (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interaction: Lupihist DM Plus Syrup 60 ml may interact with alcohol. Therefore, avoid alcohol consumption with Lupihist DM Plus Syrup 60 ml as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: Lupihist DM Plus Syrup 60 ml may have interactions with disease conditions such as liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

• DIPHENHYDRAMINE
• ESCITALOPRAM
• DESVENLAFAXINE
• VILAZODONE
• ASPIRIN
• ACETAMINOPHEN
• AMOXICILLIN
• LINEZOLID
• PHENELZINE
• SELEGILINE
• RASAGILINE
• ISOCARBOXAZID
• TRANYLCYPROMINE
• METOPROLOL
• ATENOLOL
• CARISOPRODOL
• CYCLOBENZAPRINE

• Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
• Drink plenty of fluids to avoid a dry throat while you have a cough. It also helps loosen mucus.
• Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

• Talk to your doctor if your symptoms do not improve even after taking Lupihist DM Plus Syrup 60 ml for 7 days.
• Contact a doctor immediately if you develop fever, rash or headaches after taking Lupihist DM Plus Syrup 60 ml. 

Cough: Coughing is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.