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Composition :

MIRABEGRON-50MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lupin Mira-50 Tablet

Lupin Mira-50 Tablet belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination and inability to control urination.

Lupin Mira-50 Tablet contains ‘mirabegron’ that relaxes the urinary bladder muscles, which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Lupin Mira-50 Tablet stops these sudden contractions of urinary bladder muscles, thereby enabling control over urination. Thus, it increases the amount and volume of urine that can be held by the bladder.

In some cases, Lupin Mira-50 Tablet may cause common side effects of Lupin Mira-50 Tablet are nausea, constipation, diarrhoea, headache, dizziness, and increased heart rate. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult a doctor.

Do not take Lupin Mira-50 Tablet if you are allergic to any of its ingredients. Before taking Lupin Mira-50 Tablet , inform your doctor if you have kidney disease, liver disease, hypertension, urinary retention, angioedema, or a history of heart rhythm problems (including QT prolongation). Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Uses of Lupin Mira-50 Tablet

Overactive bladder (urinary incontinency)

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, crush or break it. Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Granules for suspension: Check the label for directions and use it as advised by the doctor. Tap the bottle to loosen the granules and add 100ml of water. Shake vigorously for a minute and let it stand for 10-30 minutes. Shake again until the granules have dispersed. Take the prescribed dose as advised by the doctor.

Medicinal Benefits

Lupin Mira-50 Tablet contains 'mirabegron', which belongs to the class of medications called 'anticholinergics'. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Lupin Mira-50 Tablet can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine held by your bladder.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lupin Mira-50 Tablet

  • Nausea
  • Constipation
  • Diarrhoea
  • Headache
  • Dizziness
  • Increased heart rate

Drug Warnings

Do not take Lupin Mira-50 Tablet if you are allergic to any ingredients present in it. Before taking Lupin Mira-50 Tablet , inform your doctor if you have kidney disease, liver disease, hypertension, urinary retention, angioedema, or a history of heart rhythm problems (including QT prolongation). Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Drug-Drug Interactions

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MirabegronEliglustat
Critical
MirabegronVenetoclax
Severe

Drug-Drug Interactions

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MirabegronEliglustat
Critical
How does the drug interact with Lupin Mira-50 Tablet:
Coadministration of Eliglustat and Lupin Mira-50 Tablet can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lupin Mira-50 Tablet with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
MirabegronVenetoclax
Severe
How does the drug interact with Lupin Mira-50 Tablet:
Coadministration of Lupin Mira-50 Tablet and Venetoclax may significantly increase the blood levels and effects of Venetoclax. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possible interaction between Lupin Mira-50 Tablet and Venetoclax, but they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, diarrhea, fatigue, fever, chills, bleeding problems, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronBrexpiprazole
Severe
How does the drug interact with Lupin Mira-50 Tablet:
A combined use of Lupin Mira-50 Tablet and Brexpiprazole may increase the level of Brexpiprazole in blood. This can increase the risk or severity of side effects.

How to manage the interaction:
There could be a possible interaction between Lupin Mira-50 Tablet and Brexpipraole, it can be taken together if your doctor has advised them. However, if you experience drowsiness, fatigue, seizure, chest pain or tightness, irregular heart rates, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronTamoxifen
Severe
How does the drug interact with Lupin Mira-50 Tablet:
Coadministration of Lupin Mira-50 Tablet and Tamoxifen may reduce the effects of tamoxifen.

How to manage the interaction:
Taking Lupin Mira-50 Tablet and Tamoxifen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience painful urination, constipation, dry mouth, headache, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronPimozide
Severe
How does the drug interact with Lupin Mira-50 Tablet:
Combined use of Lupin Mira-50 Tablet and Pimozide may increase the level of pimozide in the blood. This can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Lupin Mira-50 Tablet and Pimozide may lead to an interaction but they can be taken together if your doctor has prescribed them. However, if you experience drowsiness, blurred vision, dry mouth, constipation, low blood pressure, tremors, trembling of hands, arms, legs, jaw and face, balance and Speech difficulty, or abnormal muscle movements consult a doctor. Do not discontinue any medications without consulting a doctor.
MirabegronAripiprazole
Severe
How does the drug interact with Lupin Mira-50 Tablet:
Combining Aripiprazole with Lupin Mira-50 Tablet can increase the levels of Aripiprazole in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Lupin Mira-50 Tablet and Aripiprazole together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
MirabegronThioridazine
Severe
How does the drug interact with Lupin Mira-50 Tablet:
Combine use of Lupin Mira-50 Tablet and thioridazine may raise the blood levels of thioridazine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lupin Mira-50 Tablet and thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience stomach pain, diarrhea, dehydration, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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MIRABEGRON-50MGHigh fat foods
Mild

Drug-Food Interactions

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MIRABEGRON-50MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Taking Lupin Mira-50 Tablet with High fat Food can reduce the oral absorption of Lupin Mira-50 Tablet. Avoid high fat food while being treated with Lupin Mira-50 Tablet.

Diet & Lifestyle Advise

  • Eat fresh fruits like pears, bananas, citrus fruits, and vegetables like beans and potatoes. 
  • Try to take cranberry juice as it helps in minimizing urinary infections. 
  • Avoid coffee, tea, and carbonated drinks which contain caffeine. 
  • Do not consume processed, fried, or spicy foods, as these can irritate your bladder. 
  • Limit alcohol intake as it can increase the risk of side effects.
  • Quit smoking and exercise regularly.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Lupin Mira-50 Tablet Substitute

Substitutes safety advice
  • Mirago 50 Tablet 10's

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    40.05per tablet
  • Bladmir-50 Tablet 10's

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    41.18per tablet
  • Mirakem-50 Tablet 10's

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  • Megatas 50 Tablet 10's

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    42.08per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lupin Mira-50 Tablet prevents sudden bladder muscle contractions and increases the volume and amount of urine the bladder can hold. Thus, Lupin Mira-50 Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.

If you have kidney disease, liver disease, hypertension, urinary retention, angioedema, history of heart rhythm problems (including QT prolongation), please contact a doctor before taking Lupin Mira-50 Tablet .

Ketoconazole is an antifungal medicine, and it may interact with Lupin Mira-50 Tablet . So, inform your doctor about all the prescription and non-prescription medicines before taking Lupin Mira-50 Tablet to avoid unwanted effects.

Lupin Mira-50 Tablet should be used with caution in patients with high blood pressure due to the increased risk of worsening the patient's condition. It is not recommended for use in patients with severe uncontrolled hypertension. Regular blood pressure monitoring, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • CARVEDILOL
  • METOPROLOL
  • PIMOZIDE
  • THIORIDAZINE
  • CHLORPHENIRAMINE
  • DEXTROMETHORPHAN
  • WARFARIN
  • COUMADIN
  • DESIPRAMINE
  • DIGOXIN
  • FLECAINIDE
  • PROPAFENONE
  • DARIFENACIN
  • FESOTERODINE
  • OXYBUTYNIN
  • TOLTERODINE
  • TROSPIUM

Special Advise

  • Lupin Mira-50 Tablet may raise your blood pressure. Monitor your blood pressure regularly.

Disease/Condition Glossary

Overactive bladder (OAB): In normal conditions, when the urinary bladder is filled with urine, it sends a message to the brain that an individual is ready to urinate. During the urination process, bladder muscles contract, which ultimately leads to a uniform flow of urine. Contrary to this, in an overactive bladder (OAB), the urinary bladder muscles start contracting before the urine is filled in the urinary bladder, thereby causing frequent urges to urinate.

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