LUPINIB 400MG TABLET belongs to a class of drugs known as 'anti-cancer medication', primarily used to treat various types of cancer. It is used to treat cancer of the blood (chronic myeloid leukaemia and acute lymphocytic leukaemia) and gastrointestinal stromal tumour. Cancer is a genetic change in which the cells divide uncontrollably and spread into surrounding tissues. There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc.

LUPINIB 400MG TABLET contains Imatinib, which is primarily used to treat cancer. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

You are advised to take LUPINIB 400MG TABLET for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience nausea, vomiting, oedema, fatigue, muscle cramps, musculoskeletal pain, diarrhoea, rash, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Do not take LUPINIB 400MG TABLET if you are allergic to any of its ingredients. While taking LUPINIB 400MG TABLET, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF). Regular blood tests are required to monitor liver function and blood cells in the blood while taking LUPINIB 400MG TABLET. LUPINIB 400MG TABLET can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. If you ever had a hepatitis B infection, please tell your doctor before starting LUPINIB 400MG TABLET as it can make hepatitis B active again. 

LUPINIB 400MG TABLET belongs to a class of drugs known as 'anti-cancer medication' containing Imatinib, primarily used to treat various cancer types. It is used to treat cancer of the blood (chronic myeloid leukaemia and acute lymphocytic leukaemia) and gastrointestinal stromal tumour. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

• Fatigue
• Nausea
• Vomiting
• Diarrhoea
• Muscle cramp
• Abdominal pain
• Musculoskeletal pain
• Oedema (tissue swelling)
• Rash

Do not take LUPINIB 400MG TABLET if you are allergic to any of its ingredients. LUPINIB 400MG TABLET may cause blurry vision and dizziness, so do not drive or operate any machinery which requires concentration. While taking LUPINIB 400MG TABLET, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out, as it can lead to a skin rash if you are not using a strong SPF. LUPINIB 400MG TABLET can cause leg swelling and water retention (oedema), so if you have unexpected rapid weight gain, please consult your doctor. If you ever had a hepatitis B infection, please tell your doctor before starting LUPINIB 400MG TABLET as it can make hepatitis B active again. LUPINIB 400MG TABLET may make you more susceptible to infections; consult your doctor if you develop any signs of infections, fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interaction: LUPINIB 400MG TABLET is known to interact with blood thinners (warfarin, aspirin), anti-hypertensive medicines (amlodipine, metoprolol, nifedipine), heart medicines (quinidine, atorvastatin, lovastatin, simvastatin), immuno-suppressants (cyclosporine),  antibiotics (erythromycin, telithromycin), anti-fungal medicines (itraconazole, voriconazole, ketoconazole), mental illness medicines (triazolam, alprazolam, estazolam, primidone, phenobarbital, phenytoin), anti-HIV medicines (saquinavir,  ritonavir), erectile dysfunction medicine (sildenafil). 

Drug-Food Interaction: LUPINIB 400MG TABLET is known to interact with alcohol, St. John's wort plant (a natural remedy to treat depression), and grapefruit.

Drug-Disease Interaction: Inform your doctor if you have hypothyroidism (underactive thyroid), cardiovascular disease, bone marrow suppression, liver or kidney disease, fluid retention, gastrointestinal disorders, stomach ulcer or bleeding, high blood pressure, diabetes or chemotherapy.

• WARFARIN
• ASPIRIN
• AMLODIPINE
• METOPROLOL
• NIFEDIPINE
• QUINIDINE
• ATORVASTATIN
• LOVASTATIN
• SIMVASTATIN
• CYCLOSPORINE
• ERYTHROMYCIN
• TELITHROMYCIN
• ITRACONAZOLE
• VORICONAZOLE
• KETOCONAZOLE
• TRIAZOLAM
• ALPRAZOLAM
• ESTAZOLAM
• PRIMIDONE
• PHENOBARBITAL
• PHENYTOIN
• SAQUINAVIR
• RITONAVIR
• SILDENAFIL

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate and high fibre content. Also, eat small and frequent meals for a speedy recovery.
• Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

• A regular blood test is required to monitor liver function and blood cells in blood while taking LUPINIB 400MG TABLET.
• Always take it with food and a full glass of water to prevent nausea.
• LUPINIB 400MG TABLET can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. 
• While taking LUPINIB 400MG TABLET, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out, as it can lead to a skin rash if you are not using a strong SPF.
• Do not have immunisations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterwards. 
• Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc. Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation and stem cell therapy. To date, there is no cure for cancer.

Chronic myeloid leukaemia: It is a type of cancer that affects the white blood cells and tends to progress slowly over many years. It can occur at any age but is most common in adults around 60-65.

Acute lymphocytic leukaemia: A type of leukaemia (blood cancer) that comes on quickly and is fast-growing. In acute lymphoblastic leukaemia, there are too many lymphoblasts (immature white blood cells) in the blood and bone marrow.

A gastrointestinal stromal tumour (GIST): It is a type of tumour in the stomach or small intestine. The tumours develop into the specialized cells called interstitial cells of Cajal (ICCs).