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Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy
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Composition :

HUMAN INSULIN-40IU

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Lupisulin R 40IU/ml Solution for Injection

Lupisulin R 40IU/ml Solution for Injection belongs to the group of medications called 'antidiabetics' used to treat type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition in which glucose levels are elevated in the body. In type 1 diabetes, the body does not make enough insulin (a hormone essential for glucose metabolism). In type 2 diabetes, either the body stops producing enough insulin or there is resistance to the action of insulin.

Lupisulin R 40IU/ml Solution for Injection contains 'Human Insulin'. It replaces the deficient hormone 'insulin' in patients with diabetes. Lupisulin R 40IU/ml Solution for Injection suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Lupisulin R 40IU/ml Solution for Injection ensures rapid and consistent sugar control. It starts to work within 30 min after injection, and its action lasts up to 8 hours.

Take Lupisulin R 40IU/ml Solution for Injection as prescribed by your doctor. A healthcare professional will teach you how to take the injection. It can cause some side effects, such as low blood sugar, swelling in your hands or feet, weight gain, or thickening of the skin at the injection site. Consult your doctor if any of these side effects persist or get worsen.

Do not take Lupisulin R 40IU/ml Solution for Injection if you are allergic to insulin or have an episode of hypoglycemia (low blood sugar). Talk to your doctor if you have a history of liver or kidney diseases and if you are pregnant or breastfeeding. Also, inform your doctor if you are taking any other anti-diabetic medications. If you experience an episode of hypoglycemia, seek medical attention immediately.

Uses of Lupisulin R 40IU/ml Solution for Injection

Type 1  and type 2 diabetes mellitus.

Directions for Use

Inject it subcutaneously (under the skin) in the abdomen, thigh or upper arm. Use a different place on the body every time you give an injection to prevent damage to your skin. You can take Lupisulin R 40IU/ml Solution for Injection 15 minutes before a meal or immediately after food.

Medicinal Benefits

Lupisulin R 40IU/ml Solution for Injection contains Human Insulin that is a short-acting form of insulin. It helps lower blood sugar levels in both adults and children. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. Lupisulin R 40IU/ml Solution for Injection helps in improving glycemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Lupisulin R 40IU/ml Solution for Injection if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Lupisulin R 40IU/ml Solution for Injection if you are pregnant or breastfeeding. Lupisulin R 40IU/ml Solution for Injection may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug-Drug Interactions

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Regular insulinOfloxacin
Severe

Drug-Drug Interactions

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Regular insulinOfloxacin
Severe
How does the drug interact with Lupisulin R 40IU/ml Solution for Injection 10 ml:
The use of antibiotic (quinolones) has been linked to disruptions in blood glucose maintenance. There have been reports of both decrease in glucose and increase in glucose, mainly in diabetic individuals undergoing concurrent therapy with insulin or an oral antidiabetic medication.

How to manage the interaction:
Blood glucose should be closely watched, particularly if the patient is elderly, has renal impairment, or is very sick. When using insulin and insulin secretagogues (such as meglitinides and sulfonylureas) together, extra vigilance is suggested due to the possibility of severe and potentially hypoglycemia.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates, fibre, fruits, whole grains, and vegetables in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk for at least a few minutes to complement treatment with Lupisulin R 40IU/ml Solution for Injection.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Lupisulin R 40IU/ml Solution for Injection Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lupisulin R 40IU/ml Solution for Injection works by increasing the glucose uptake by fats and muscles, suppresses the production of glucose in the liver, and also the formation of glycogen from glucose. Thereby, Lupisulin R 40IU/ml Solution for Injection helps in reducing the glucose levels in the blood.

In hypoglycemia, blood sugar levels decrease significantly. It causes symptoms such as dizziness, headache, sweating, hunger, loss of consciousness, rapid breathing, or seizure (fits). In such cases, seek medical attention immediately.

If you experience low blood sugar, eat glucose tablets, chocolate, or another high-sugar snack, such as a sweet or biscuit. Use a blood glucose monitor to test your blood sugar levels after 15 minutes if possible.

Do not stop taking Lupisulin R 40IU/ml Solution for Injection without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Lupisulin R 40IU/ml Solution for Injection for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lupisulin R 40IU/ml Solution for Injection.

Drug-Drug Interactions Checker List

  • ROSIGLITAZONE
  • PIOGLITAZONE
  • LEVOFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN
  • ENALAPRIL
  • LISINOPRIL
  • CAPTOPRIL
  • LOSARTAN
  • VALSARTAN
  • PROPRANOLOL
  • METOPROLOL

Special Advise

If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.  

Disease/Condition Glossary

Diabetes mellitus: It is a metabolic disease that causes high blood sugar levels. Type 1 diabetes (juvenile diabetes) is an autoimmune disease in which the immune system attacks and destroys its own cells in the pancreas, thereby producing no insulin. It often occurs in childhood. Type 2 diabetes (adult-onset diabetes) occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas produces little or no insulin at all. Symptoms include frequent urination, increased thirst, hunger, and blurred vision. The treatment includes oral glucose-lowering medicines and insulin shots. 

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