Lupituss CPM Suspension 100 ml

Written By Veda Maddala , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

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MRP ₹211

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About Lupituss CPM Suspension

Lupituss CPM Suspension is a combination medication primarily used to treat dry cough. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Dry cough is tickly and doesn't produce vicious or thick mucus.

Lupituss CPM Suspension is a combination of two drugs, namely: Levocloperastine hydrochloride (cough suppressant) and Chlorpheniramine maleate (antihistamine). Levocloperastine hydrochloride works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the need to cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.

Take Lupituss CPM Suspension as prescribed. Your doctor will recommend how often you need to take Lupituss CPM Suspension based on your medical condition. Some people may experience headache, dizziness, numbness, drowsiness, or nausea. Most of these side effects of Lupituss CPM Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Lupituss CPM Suspension or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupituss CPM Suspension . Lupituss CPM Suspension is not recommended for children unless advised by a doctor. Drink plenty of fluids while taking Lupituss CPM Suspension to loosen mucus. Lupituss CPM Suspension may cause drowsiness, so drive only if you are alert. Avoid alcohol consumption as it may lead to increased dizziness.

Uses of Lupituss CPM Suspension

Dry cough

Directions for Use

Take Lupituss CPM Suspension with or without food as advised by the doctor. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Lupituss CPM Suspension contains Levocloperastine hydrochloride and Chlorpheniramine maleate used to treat dry cough. Levocloperastine hydrochloride is a cough suppressant that blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the need to cough. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Storage

Keep Lupituss CPM Suspension out of the sight and reach of children.

Side effects of Lupituss CPM Suspension 100 ml

Sedation

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drowsiness

Get enough sleep. Maintain a regular sleep cycle.
Eat a healthy diet and exercise regularly.
Manage stress with yoga or meditation.
Limit alcohol and caffeine.
Avoid driving or operating machinery unless you are alert.

Sleepiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Tiredness And Fatigue

Stay hydrated by drinking adequate fluids.
Exercise regularly and maintain a healthy weight.
Get enough sleep.
Eat a nutritious diet to reduce the chance of developing vitamin or mineral deficiencies or electrolyte imbalances which could cause tiredness.
Try relaxation techniques like deep breathing, meditation or yoga.
Avoid tobacco and alcohol.

Sedative Effects

Stomach Problems

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

If you are allergic to Lupituss CPM Suspension or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupituss CPM Suspension . Lupituss CPM Suspension is not recommended for children unless advised by a doctor. Drink plenty of fluids while taking Lupituss CPM Suspension to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupituss CPM Suspension .

Drug-Drug Interactions

ChlorpheniraminePotassium chloride

Critical

ChlorpheniraminePotassium citrate

Critical

Drug-Drug Interactions

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ChlorpheniraminePotassium chloride

Critical

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Lupituss CPM Suspension 100 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.

ChlorpheniraminePotassium citrate

Critical

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Lupituss CPM Suspension 100 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

ChlorpheniramineTopiramate

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml with Topiramate can increase the risk of side effects including high body temperatures and decreased sweating, sun stroke.

How to manage the interaction:
Although taking Lupituss CPM Suspension 100 ml and Topiramate together can result in an interaction, it can be taken if your doctor has advised it. During warm weather and when exercising, you should drink lots of fluids. If your sweating is less than usual or you have a fever, if you feel lightheaded or dizzy, consult a doctor. Avoid activities requiring mental attention such as driving or operating dangerous machinery. Do not discontinue any medications without a doctor's advice.

ChlorpheniramineEluxadoline

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml with Eluxadoline can increase the levels of both the medications, which may the risk of constipation and other stomach related problems.

How to manage the interaction:
There may be a possibility of interaction between Lupituss CPM Suspension 100 ml and Eluxadoline, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

ChlorpheniramineIdelalisib

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml with Idelalisib together can increase the levels of Lupituss CPM Suspension 100 ml which may lead to side effects.

How to manage the interaction:
Although taking Lupituss CPM Suspension 100 ml and Idelalisib together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting the doctor.

ChlorpheniramineSodium oxybate

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml with Sodium oxybate can enhance the risk of side effects.

How to manage the interaction:
Co-administration of Lupituss CPM Suspension 100 ml with Sodium oxybate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience- drowsiness, dizziness, lightheadedness, confusion, breathing difficulty, and impairment in thinking, judgment, and motor coordination, consult the doctor. You should take care when getting up from a sitting or lying posture, and avoid operating machinery, driving, or participating in any potentially dangerous activity requiring mental attention and motor coordination for at least six hours after taking sodium oxybate.

ChlorpheniramineMexiletine

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Co-administration of Lupituss CPM Suspension 100 ml with mexiletine may cause the side effects of mexiletine.

How to manage the interaction:
Although taking Lupituss CPM Suspension 100 ml and mexiletine together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

ChlorpheniramineKetamine

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Co-administration of Lupituss CPM Suspension 100 ml with Ketamine can increase the risk of side effects.

How to manage the interaction:
Taking Lupituss CPM Suspension 100 ml and Ketamine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, and breathing difficulty. Avoid activities requiring mental focus such as driving, operating dangerous machinery. Do not discontinue any medications without a doctor's advice.

ChlorpheniramineIsocarboxazid

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Co-administration of Lupituss CPM Suspension 100 ml with Isocarboxazid can increase the risk of side effects.

How to manage the interaction:
Taking Lupituss CPM Suspension 100 ml with Isocarboxazid can result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of these symptoms - dizziness, drowsiness, confusion, disorientation, memory problems, blurred vision, dry mouth, constipation, heat intolerance, flushing, decreased sweating, difficulty urinating, rapid heartbeat, - make sure to consult the doctor right away. Do not stop using any medications without talking to a doctor.

ChlorpheniramineEthanol

Severe

How does the drug interact with Lupituss CPM Suspension 100 ml:
Taking Lupituss CPM Suspension 100 ml and Ethanol together may increases the risk of side effects.

How to manage the interaction:
Although taking Lupituss CPM Suspension 100 ml and Ethanol together can result in an interaction, it can be taken if your doctor has advised it. Avoid physical activities such as driving or operating machinery. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
Drink plenty of fluids to avoid dry throat while coughing. It also helps loosen mucus.
Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Side Effects of Lupituss CPM Suspension

Headache
Dizziness
Numbness
Drowsiness
Nausea

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Lupituss CPM Suspension work?

Lupituss CPM Suspension contains Levocloperastine hydrochloride and Chlorpheniramine maleate. Levocloperastine hydrochloride is a cough suppressant that blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the need to cough. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Is Lupituss CPM Suspension used to treat allergic symptoms?

Lupituss CPM Suspension may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Lupituss CPM Suspension contains Chlorpheniramine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

Does Lupituss CPM Suspension cause headache?

Lupituss CPM Suspension may cause headache as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.

How long should I take Lupituss CPM Suspension ?

You are recommended to take Lupituss CPM Suspension for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Lupituss CPM Suspension , please consult your doctor.

Can I stop taking Lupituss CPM Suspension on my own?

You are not recommended to stop taking Lupituss CPM Suspension without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Lupituss CPM Suspension for as long as your doctor has prescribed it, and if you experience any difficulty while taking Lupituss CPM Suspension , please consult your doctor.

Drug-Drug Interactions Checker List

DIPHENHYDRAMINE
CETIRIZINE
DULOXETINE
ALPRAZOLAM

Disease/Condition Glossary

Cough: Coughing is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Dry cough is tickly and doesn't produce vicious or thick mucus. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or a minor infection in the respiratory tract and yellow or green mucus indicates a respiratory infection.