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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS

About Luprova 22.5 Injection 1's

Luprova 22.5 Injection 1's belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Luprova 22.5 Injection 1's contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Take Luprova 22.5 Injection 1's as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Luprova 22.5 Injection 1's include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

To treat your condition effectually continue taking Luprova 22.5 Injection 1's for as long as your doctor has prescribed. Do not stop Luprova 22.5 Injection 1's midway.  Avoid taking Luprova 22.5 Injection 1's if you are pregnant or breastfeeding because this Luprova 22.5 Injection 1's can cause harmful effects on the unborn baby. Both women and men using this Luprova 22.5 Injection 1's should use birth control to avoid pregnancy. Luprova 22.5 Injection 1's may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Luprova 22.5 Injection 1's is not recommended for children below two years of age. Luprova 22.5 Injection 1's may make you feel dizzy, hence drive when you are alert only.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Luprova 22.5 Injection 1's

Prostate cancer, Breast cancer, Endometriosis, Precocious puberty

Medicinal Benefits

Luprova 22.5 Injection 1's contains Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Luprova 22.5 Injection 1's is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Luprova 22.5 Injection 1's works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Luprova 22.5 Injection 1's reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis and breast cancer.

Side Effects of Luprova 22.5 Injection 1's

  • Weight changes
  • Hot flushes
  • Muscle weakness
  • Bone Pain
  • Loss of interest in sexual intercourse
  • Inability to have an erection
  • Tiredness
  • Difficulty sleeping
  • Headaches
  • Breast tenderness
  • Changes in breast size
  • Mood swings
  • Abdominal pain
  • Vomiting (feeling sick)
  • Acne
  • Vaginal Bleeding 
  • Spotting
  • Injection site reactions (skin hardening, redness, pain, abscesses, swelling, nodules, ulcers and skin damage)

Directions for Use

Luprova 22.5 Injection 1's will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Luprova 22.5 Injection 1's or any other medicines, please tell your doctor. Luprova 22.5 Injection 1's can affect the unborn baby when used in pregnancy. Hence, Luprova 22.5 Injection 1's is not indicated for use in pregnancy and breastfeeding women. If you are using Luprova 22.5 Injection 1's, make sure to use reliable forms of contraception to prevent pregnancy during the course. Luprova 22.5 Injection 1's may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Use the Luprova 22.5 Injection 1's with caution in elderly patients and children. Luprova 22.5 Injection 1's is not recommended for children younger than two years of age. Your symptoms may become temporarily worse when you first start taking Luprova 22.5 Injection 1's. Inform your doctor if this continues for longer than 2 months. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting Luprova 22.5 Injection 1's, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Luprova 22.5 Injection 1's may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Luprova 22.5 Injection 1's. Luprova 22.5 Injection 1's can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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LeuprorelinPimozide
Critical
LeuprorelinVandetanib
Critical

Drug-Drug Interactions

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LeuprorelinPimozide
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking Luprova 22.5 Injection 1's with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking Luprova 22.5 Injection 1's with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCitalopram
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Coadministration of Luprova 22.5 Injection 1's and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinIbutilide
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinNilotinib
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Luprova 22.5 Injection 1's with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinCisapride
Critical
How does the drug interact with Luprova 22.5 Injection 1's:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Luprova 22.5 Injection 1's with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinProcainamide
Severe
How does the drug interact with Luprova 22.5 Injection 1's:
Taking leuprolide with procainamide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Luprova 22.5 Injection 1's and procainamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • AMIODARONE
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • PREDNISOLONE
  • MOXIFLOXACIN
  • METHADONE
  • CITALOPRAM
  • ESCITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests to monitor your liver health since Luprova 22.5 Injection 1's may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
  • Luprova 22.5 Injection 1's may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting Luprova 22.5 Injection 1's.
  • Your doctor may advise blood tests, electrolyte levels and regular examinations of the prostate.
  • It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.

Author Details

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Disease/Condition Glossary

Prostate cancer: It is the cancer of the prostate gland (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. The symptoms include difficulty in urination, pain, numbness or sexual problems. It is the most common type of cancer in men.

Breast cancer: It is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other parts of the body.

Endometriosis: It is a disorder in which tissue lining the uterus grows outside the uterine cavity. It commonly involves ovaries, fallopian tubes and the tissue lining the pelvis. Symptoms of endometriosis include pain and irregular periods.

Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon. If puberty begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Symptoms in a girl include first period and breast development, whereas, in a boy, it causes enlarged testicles and penis, deepening voice and facial hair.

Luprova 22.5 Injection 1's Substitute

Substitutes safety advice
  • LUPRODEX 22.5MG INJECTION

    by AYUR

    15291.80per tablet
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    12228.70per tablet
  • ELIGARD 22.5MG INJECTION

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  • Leuprosta Depot 22.5 mg Injection 1's

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  • Leprol 22.5 mg Injection 1's

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