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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About LYSOFLAM MR TABLET

LYSOFLAM MR TABLET belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

LYSOFLAM MR TABLET contains Diclofenac and Metaxalone. Diclofenac works by blocking the effect of chemical messengers that cause pain and inflammation.Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helps in maintaining muscle strength and relieves muscle spasms or stiffness. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasms.

You are advised to take LYSOFLAM MR TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, LYSOFLAM MR TABLET may cause common side-effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. LYSOFLAM MR TABLET may cause drowsiness and dizziness, so drive only if you are alert. LYSOFLAM MR TABLET should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with LYSOFLAM MR TABLET as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of LYSOFLAM MR TABLET

Pain due to muscle spasm

Medicinal Benefits

LYSOFLAM MR TABLET is a combination of two drugs: Diclofenac and Metaxalone. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug), and metaxalone is a skeletal muscle relaxant. LYSOFLAM MR TABLET is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Diclofenac works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Metaxalone works on the centres of the spinal cord and brain, thereby helps in maintaining muscle strength and relieves muscle spasms or stiffness. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasms.

Side Effects of LYSOFLAM MR TABLET

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache

Directions for Use

Swallow LYSOFLAM MR TABLET as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you have had any recent heart surgery, do not take LYSOFLAM MR TABLET unless advised by the doctor as it may increase the risk of fatal heart attack or stroke. Do not take LYSOFLAM MR TABLET if you are allergic to any of its components, have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor before taking LYSOFLAM MR TABLET if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. LYSOFLAM MR TABLET may cause drowsiness and dizziness, so drive only if you are alert. LYSOFLAM MR TABLET should not be given to children as safety has not been established. Avoid consuming alcohol along with LYSOFLAM MR TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking LYSOFLAM MR TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with LYSOFLAM MR TABLET unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Therapeutic Class

ANALGESICS

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacAmiloride
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with LYSOFLAM MR TABLET is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacAmiloride
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking amiloride with LYSOFLAM MR TABLET can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between LYSOFLAM MR TABLET and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacIndometacin
Severe
How does the drug interact with LYSOFLAM MR TABLET:
The combined use of LYSOFLAM MR TABLET and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacFondaparinux
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Coadministration of LYSOFLAM MR TABLET with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between LYSOFLAM MR TABLET and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking Valdecoxib with LYSOFLAM MR TABLET may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between LYSOFLAM MR TABLET and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co administration of LYSOFLAM MR TABLET with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacCelecoxib
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between LYSOFLAM MR TABLET and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacIbuprofen
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking LYSOFLAM MR TABLET and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacApixaban
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between LYSOFLAM MR TABLET and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacMethotrexate
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of methotrexate with LYSOFLAM MR TABLET can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and LYSOFLAM MR TABLET, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • IBUPROFEN
  • ASPIRIN
  • NAPROXEN
  • ACETAMINOPHEN
  • HYDROCODONE
  • OXYCODONE
  • TRAMADOL
  • HYDROCHLOROTHIAZIDE
  • LISINOPRIL
  • METOPROLOL
  • PREDNISONE
  • RIVAROXABAN
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • GABAPENTIN
  • CLONAZEPAM
  • PREGABALIN
  • ESCITALOPRAM
  • SERTRALINE
  • DIAZEPAM
  • ALPRAZOLAM
  • LORAZEPAM

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Muscle spasm: It is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Whereas, exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain.

LYSOFLAM MR TABLET Substitute

Substitutes safety advice
  • Flexura D Tablet 10's

    21.60per tablet
  • Mobiswift-D Tablet 10's

    21.60per tablet
  • Myospas D Tablet 10's

    by MAYBELLINE

    28.17per tablet
  • Dfo Mr Tablet 10's

    by AYUR

    11.84per tablet
  • Flexalone D Tablet 10's

    14.40per tablet
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