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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Cachet Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lysoflam Tablet

Lysoflam Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 

Lysoflam Tablet consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.

Lysoflam Tablet should be taken as prescribed by your doctor.  Sometimes it may cause certain common side effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Lysoflam Tablet may cause drowsiness and dizziness, so drive with caution. Lysoflam Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Lysoflam Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions. It is advised not to take more than the prescribed dose of medicine and for a longer period. 

Uses of Lysoflam Tablet

Pain and inflammation associated with musculoskeletal and joint disorders.

Directions for Use

Take Lysoflam Tablet with food to prevent stomach upset. Swallow Lysoflam Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Lysoflam Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol, and Trypsin chymotrypsin. Lysoflam Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Avoid taking Lysoflam Tablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, or severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, a habit of smoking, or liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Lysoflam Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. This medicine is not recommended for use in children as safety is not established. It is advised not to take more than the prescribed dose of Lysoflam Tablet for a prolonged period.

Drug-Drug Interactions

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DiclofenacVorapaxar
Severe

Drug-Drug Interactions

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How does the drug interact with Lysoflam Tablet:
Co-administration of Lysoflam Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Lysoflam Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacVorapaxar
Severe
How does the drug interact with Lysoflam Tablet:
Taking Lysoflam Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Lysoflam Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lysoflam Tablet:
Co-administration of Lysoflam Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Lysoflam Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Lysoflam Tablet:
Coadministration of Lysoflam Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lysoflam Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacSulindac
Severe
How does the drug interact with Lysoflam Tablet:
Co-administration of Lysoflam Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Lysoflam Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lysoflam Tablet:
Coadministration of Lysoflam Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Lysoflam Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lysoflam Tablet:
Co-administration of Lysoflam Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Lysoflam Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lysoflam Tablet:
Taking Lysoflam Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Lysoflam Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPonatinib
Severe
How does the drug interact with Lysoflam Tablet:
Taking Lysoflam Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Lysoflam Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lysoflam Tablet:
Taking acalabrutinib together with Lysoflam Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Lysoflam Tablet and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lysoflam Tablet contains Diclofenac, Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Do not take any other medicines for pain relief, such as NSAIDs along with Lysoflam Tablet , unless prescribed by a doctor, as it might increase the risk of side effects.

Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Lysoflam Tablet might cause serious liver damage or allergic reactions like rash, difficulty breathing, and swelling of the face, throat, and mouth. Therefore, Lysoflam Tablet should not be taken for longer durations unless prescribed by the doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CLOPIDOGREL
  • CHLORAMPHENICOL
  • DIGOXIN
  • METHOTREXATE
  • ZIDOVUDINE
  • CICLOSPORIN
  • WARFARIN

Special Advise

 

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis symptoms include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

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